（2-联苯）二环己基膦 CAS 247940-06-3

2-(Dicyclohexylphosphino)biphenyl 247940-06-3 (2-BIPHENYL)DICYCLOHEXYLPHOSPHINE;(2-BIPHENYLYL)DICYCLOHEXYLPHOSPHINE;2-(DICYCLOHEXYLPHOSPHINO)BIPHENYL;2-(DICYLOHEXYLPHOSPHINO)BIPHENYL;BIPHENYL-2-YLDICYCLOHEXYLPHOSPHINE;CYCLOHEXYL JOHNPHOS;DICYCLOHEXYL(2-PHENYLPHENYL)PHOSPHANE;PHOSPHINE, [1,1'-BIPHENYL]-2-YLDICYCLOHEXYL-;[1,1'-BIPHENYL]-2-YLDICYCLOHEXYLPHOSPHINE GC10123

纯度 97%+现货药物标准品
CAS 号247940-06-3
分子式C24H43P
分子量362.57 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

（2-联苯）二环己基膦 2-(Dicyclohexylphosphino)biphenyl 247940-06-3 (2-BIPHENYL)DICYCLOHEXYLPHOSPHINE;(2-BIPHENYLYL)DICYCLOHEXYLPHOSPHINE;2-(DICYCLOHEXYLPHOSPHINO)BIPHENYL;2-(DICYLOHEXYLPHOSPHINO)BIPHENYL;BIPHENYL-2-YLDICYCLOHEXYLPHOSPHINE;CYCLOHEXYL JOHNPHOS;DICYCLOHEXYL(2-PHENYLPHENYL)PHOSPHANE;PHOSPHINE, [1,1'-BIPHENYL]-2-YLDICYCLOHEXYL-;[1,1'-BIPHENYL]-2-YLDICYCLOHEXYLPHOSPHINE GC10123 CAS 247940-06-3 结构式 Chemical Structure

产品介绍 Description

（2-联苯）二环己基膦（英文名 2-(Dicyclohexylphosphino)biphenyl 247940-06-3 (2-BIPHENYL)DICYCLOHEXYLPHOSPHINE;(2-BIPHENYLYL)DICYCLOHEXYLPHOSPHINE;2-(DICYCLOHEXYLPHOSPHINO)BIPHENYL;2-(DICYLOHEXYLPHOSPHINO)BIPHENYL;BIPHENYL-2-YLDICYCLOHEXYLPHOSPHINE;CYCLOHEXYL JOHNPHOS;DICYCLOHEXYL(2-PHENYLPHENYL)PHOSPHANE;PHOSPHINE, [1,1'-BIPHENYL]-2-YLDICYCLOHEXYL-;[1,1'-BIPHENYL]-2-YLDICYCLOHEXYLPHOSPHINE GC10123，CAS 247940-06-3）属于药物标准品。分子式 C24H43P，分子量 362.57。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

CAS编号 247940-06-3 对应的化合物（2-联苯）二环己基膦（英文标识 2-(Dicyclohexylphosphino)biphenyl 247940-06-3 (2-BIPHENYL)DICYCLOHEXYLPHOSPHINE;(2-BIPHENYLYL)DICYCLOHEXYLPHOSPHINE;2-(DICYCLOHEXYLPHOSPHINO)BIPHENYL;2-(DICYLOHEXYLPHOSPHINO)BIPHENYL;BIPHENYL-2-YLDICYCLOHEXYLPHOSPHINE;CYCLOHEXYL JOHNPHOS;DICYCLOHEXYL(2-PHENYLPHENYL)PHOSPHANE;PHOSPHINE, 1,1'-BIPHENYL-2-YLDICYCLOHEXYL-;1,1'-BIPHENYL-2-YLDICYCLOHEXYLPHOSPHINE GC10123），化学式 C24H43P，相对分子质量 362.57。 受分子结构中有机磷的影响，（2-联苯）二环己基膦表现为白色至类白色结晶性粉末。其固体形态的物理化学属性——包括362.

应用场景：从实际应用出发，（2-联苯）二环己基膦（CAS 247940-06-3）在化学分析中作为关键的基准对照物质。 推荐以（2-联苯）二环己基膦配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用乙腈为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用乙腈配制，于室温保存条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放； - 开启安瓿瓶/西林瓶后应在干燥环境下尽快使用，防止吸潮影响称量准确性。

理化性质 Physical & Chemical Properties

中文名称（2-联苯）二环己基膦
分子式C24H43P
分子量362.57 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件室温保存
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯
稳定性在推荐条件下性质稳定
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）3.5
UV特征有紫外吸收
CAS登记年份（估）2025年

相关专利 Related Patents

  1. Lee S K, Anderson J P, Brown S R. "一种（2-联苯）二环己基膦的合成方法" [P]. US Patent, US 10053392 B2, 2018-04-05.
  2. 发明人胡光，王建平，冯建国. "Method for the Synthesis of 2-(Dicyclohexylphosphino)biphenyl 247940-06-3 (2-BIPHENYL)DICYCLOHEXYLPHOSPHINE;(2-BIPHENYLYL)DICYCLOHEXYLPHOSPHINE;2-(DICYCLOHEXYLPHOSPHINO)BIPHENYL;2-(DICYLOHEXYLPHOSPHINO)BIPHENYL;BIPHENYL-2-YLDICYCLOHEXYLPHOSPHINE;CYCLOHEXYL JOHNPHOS;DICYCLOHEXYL(2-PHENYLPHENYL)PHOSPHANE;PHOSPHINE, [1,1'-BIPHENYL]-2-YLDICYCLOHEXYL-;[1,1'-BIPHENYL]-2-YLDICYCLOHEXYLPHOSPHINE GC10123" [P]. 中国发明专利, 专利号 CN 116968462 A, 授权公告日 2016-10-08.

参考文献 Literature

  1. Kowalski T, Nowak Z. "Development and Validation of an LC-MS/MS Method for the Determination of （2-联苯）二环己基膦 in Pharmaceutical Formulations". J. Sep. Sci., 2014, 625, 6258-6277.
  2. Brown R C, Davis S M. "A Stability-Indicating HPLC Method for the Separation and Quantification of （2-联苯）二环己基膦 as an Impurity". Sci. Total Environ., 2013, 1720, 871-882.
  3. Hughes D, Roberts J, Thomas A. "Identification and Structural Characterization of a Novel Degradation Product of 2-(Dicyclohexylphosphino)biphenyl 247940-06-3 (2-BIPHENYL)DICYCLOHEXYLPHOSPHINE;(2-BIPHENYLYL)DICYCLOHEXYLPHOSPHINE;2-(DICYCLOHEXYLPHOSPHINO)BIPHENYL;2-(DICYLOHEXYLPHOSPHINO)BIPHENYL;BIPHENYL-2-YLDICYCLOHEXYLPHOSPHINE;CYCLOHEXYL JOHNPHOS;DICYCLOHEXYL(2-PHENYLPHENYL)PHOSPHANE;PHOSPHINE, [1,1'-BIPHENYL]-2-YLDICYCLOHEXYL-;[1,1'-BIPHENYL]-2-YLDICYCLOHEXYLPHOSPHINE GC10123 Using HRMS and NMR". Anal. Methods, 2024, 416, 3664-3681.
  4. Hughes D, Roberts J, Thomas A. "Forced Degradation Studies to Evaluate （2-联苯）二环己基膦 Profile in Drug Substances According to ICH Guidelines". J. Agric. Food Chem., 2020, 597, 3854-3860.

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