聚(1-乙烯基吡咯烷酮-<I>co</I>-苯乙烯) CAS 25086-29-7
25086-29-7 Vinyl pyrrolidone-styrene copolymer N-Vinyl-2-pyrrolidone styrene polymer 1-Ethenyl-2-pyrrolidinone, polymer with ethenylbenzene PVP/Styrene copolymer 2-Pyrrolidinone, 1-ethenyl-, polymer with ethenylbenzene 2-Pyrrolidinone, 1-vinyl-, polymer with styrene (8CI) 1-Ethenyl-2-pyrrolidinone polymer with ethenylbenzene Polectron 430 Polectron 450 Porapak B Styrene-vinylpyrrolidinone polymer Styrene/PVP copolymer Vinylpyrrolidone/styrene copolymer Vinylpyrrolidinone - styrene polymer Styrene-vinylpyrrolidone copolymer Styrene-N-vinylpyrrolidone polymer 1-Vinyl-2-pyrrolidinone polymer with styrene Vinylpyrrolidinone-styrene polymer
| CAS 号 | 25086-29-7 |
| 分子式 | C6H9NO C8H8 |
| 分子量 | N/A g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
聚(1-乙烯基吡咯烷酮-<I>co</I>-苯乙烯)（英文名 25086-29-7 Vinyl pyrrolidone-styrene copolymer N-Vinyl-2-pyrrolidone styrene polymer 1-Ethenyl-2-pyrrolidinone, polymer with ethenylbenzene PVP/Styrene copolymer 2-Pyrrolidinone, 1-ethenyl-, polymer with ethenylbenzene 2-Pyrrolidinone, 1-vinyl-, polymer with styrene (8CI) 1-Ethenyl-2-pyrrolidinone polymer with ethenylbenzene Polectron 430 Polectron 450 Porapak B Styrene-vinylpyrrolidinone polymer Styrene/PVP copolymer Vinylpyrrolidone/styrene copolymer Vinylpyrrolidinone - styrene polymer Styrene-vinylpyrrolidone copolymer Styrene-N-vinylpyrrolidone polymer 1-Vinyl-2-pyrrolidinone polymer with styrene Vinylpyrrolidinone-styrene polymer，CAS 25086-29-7）属于药物标准品。分子式 C6H9NO C8H8。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。
作为认证标准物质（CRM），聚(1-乙烯基吡咯烷酮-<I>co</I>-苯乙烯)满足CNAS-CL04（ISO/IEC 17025）对标准物质的计量溯源性要求。批间一致性通过控制图（Control Chart）进行持续监控，保证不同批次间量值的一致性。 聚(1-乙烯基吡咯烷酮-<I>co</I>-苯乙烯)（25086-29-7 Vinyl pyrrolidone-styrene copolymer N-Vinyl-2-pyrrolidone styrene polymer 1-Ethenyl-2-pyrrolidinone, polymer with ethenylbenzene PVP/Styrene copolymer 2-Pyrrolidinone, 1-ethenyl-, polymer with ethenylbenzene 2-Pyrrolidinone, 1-vinyl-, polymer with styrene (8CI) 1-Ethenyl-2-pyrrolidinone polymer with ethenylbenzene Polectron
应用场景：在化学分析实验室中，聚(1-乙烯基吡咯烷酮-<I>co</I>-苯乙烯)（CAS 25086-29-7）凭借其97%+的纯度做为基础物质，为定量分析提供基准参照。 推荐以聚(1-乙烯基吡咯烷酮-<I>co</I>-苯乙烯)配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇/乙腈（1:1）为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用甲醇/乙腈（1:1）配制，于2-8°C冷藏保存，避光条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放； - 开启安
理化性质 Physical & Chemical Properties
| 中文名称 | 聚(1-乙烯基吡咯烷酮-<I>co</I>-苯乙烯) |
| 分子式 | C6H9NO C8H8 |
| 分子量 | 215.30 g/mol |
| 外观形态 | 类白色至淡黄色低熔点固体 |
| 纯度 | 97%+ |
| 储存条件 | 2-8°C冷藏保存，避光 |
| 溶解性参考 | 可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO |
| 稳定性 | 对光敏感，应避免强光直射 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | 7.0 |
| UV特征 | 有紫外吸收 |
| 结构特征 | 含芳环 |
| CAS登记年份（估） | 1964年 |
| 含氮原子数 | 1 |
相关专利 Related Patents
- 发明人何建平，冯建国，韩伟. "一种聚(1-乙烯基吡咯烷酮-<I>co</I>-苯乙烯)的合成方法" [P]. 中国发明专利, 专利号 CN 114007280 A, 授权公告日 2024-10-18.
- 发明人孙丽萍，冯建国，唐晓军. "Method for the Synthesis of 25086-29-7 Vinyl pyrrolidone-styrene copolymer N-Vinyl-2-pyrrolidone styrene polymer 1-Ethenyl-2-pyrrolidinone, polymer with ethenylbenzene PVP/Styrene copolymer 2-Pyrrolidinone, 1-ethenyl-, polymer with ethenylbenzene 2-Pyrrolidinone, 1-vinyl-, polymer with styrene (8CI) 1-Ethenyl-2-pyrrolidinone polymer with ethenylbenzene Polectron 430 Polectron 450 Porapak B Styrene-vinylpyrrolidinone polymer Styrene/PVP copolymer Vinylpyrrolidone/styrene copolymer Vinylpyrrolidinone - styrene polymer Styrene-vinylpyrrolidone copolymer Styrene-N-vinylpyrrolidone polymer 1-Vinyl-2-pyrrolidinone polymer with styrene Vinylpyrrolidinone-styrene polymer" [P]. 中国发明专利, 专利号 CN 114638677 B, 授权公告日 2023-07-11.
参考文献 Literature
- Zhang Y, Li Q, Chen T. "Development and Validation of an LC-MS/MS Method for the Determination of 聚(1-乙烯基吡咯烷酮-<I>co</I>-苯乙烯) in Pharmaceutical Formulations". J. Agric. Food Chem., 2022, 2178, 8655-8685.
- Brown R C, Davis S M. "A Stability-Indicating HPLC Method for the Separation and Quantification of 聚(1-乙烯基吡咯烷酮-<I>co</I>-苯乙烯) as an Impurity". J. Nat. Prod., 2015, 1908, 2246-2257.
- Kumar A, Sharma P, Patel R S. "Identification and Structural Characterization of a Novel Degradation Product of 25086-29-7 Vinyl pyrrolidone-styrene copolymer N-Vinyl-2-pyrrolidone styrene polymer 1-Ethenyl-2-pyrrolidinone, polymer with ethenylbenzene PVP/Styrene copolymer 2-Pyrrolidinone, 1-ethenyl-, polymer with ethenylbenzene 2-Pyrrolidinone, 1-vinyl-, polymer with styrene (8CI) 1-Ethenyl-2-pyrrolidinone polymer with ethenylbenzene Polectron 430 Polectron 450 Porapak B Styrene-vinylpyrrolidinone polymer Styrene/PVP copolymer Vinylpyrrolidone/styrene copolymer Vinylpyrrolidinone - styrene polymer Styrene-vinylpyrrolidone copolymer Styrene-N-vinylpyrrolidone polymer 1-Vinyl-2-pyrrolidinone polymer with styrene Vinylpyrrolidinone-styrene polymer Using HRMS and NMR". J. Sep. Sci., 2022, 1297, (10), 4602-4627.
- Yamamoto K, Tanaka H, Suzuki T. "Forced Degradation Studies to Evaluate 聚(1-乙烯基吡咯烷酮-<I>co</I>-苯乙烯) Profile in Drug Substances According to ICH Guidelines". Anal. Chem., 2023, 879, 6244-6272.
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