聚(四氢呋喃) CAS 25190-06-1
25190-06-1 Polytetramethylene glycol Glycols, polytetramethylene Poly(oxy-1,4-butanediyl), alpha-hydro-omega-hydroxy- B 2000 Hiprene MC 532 Polifurit Polybutylene glycol Poly(butylene oxide) Polyfurit Polyfurit 1000 Polyfurite Polymeg Polymeg 1000 Polymeg 1020 Polymeg 2000 Polymeg 2010 Polymeg 600 Polymeg 650 Poly(oxybutylene) glycol Poly(oxy-1,4-butylene) glycol Poly(oxytetramethylene) Poly(oxytetramethylene)diol Poly(tetramethylene ether) Poly(tetramethylene ether)diol Poly(tetramethylene ether)glycol Poly(tetramethylene glycol) Poly(tetramethylene oxide) Poly(tetramethylene oxide) glycol PTG 100 PTG 200 PTG 300 PTG 400 PTG 500 PTG 500p PTMG PTMG 1000 PTMG 2000 Qo polymeg Qo polymeg 1000 Teracol Teracol 1000 Teracol 2000 Teracol 30 Teracol 650 Terathane Terathane 1000 Terathane 2900 Tetrahydrofuran homopolymer SRU THF polymer, SRU CCRIS 8980
| CAS 号 | 25190-06-1 |
| 分子式 | C4H10O2 |
| 分子量 | 90.12 g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
聚(四氢呋喃)（英文名 25190-06-1 Polytetramethylene glycol Glycols, polytetramethylene Poly(oxy-1,4-butanediyl), alpha-hydro-omega-hydroxy- B 2000 Hiprene MC 532 Polifurit Polybutylene glycol Poly(butylene oxide) Polyfurit Polyfurit 1000 Polyfurite Polymeg Polymeg 1000 Polymeg 1020 Polymeg 2000 Polymeg 2010 Polymeg 600 Polymeg 650 Poly(oxybutylene) glycol Poly(oxy-1,4-butylene) glycol Poly(oxytetramethylene) Poly(oxytetramethylene)diol Poly(tetramethylene ether) Poly(tetramethylene ether)diol Poly(tetramethylene ether)glycol Poly(tetramethylene glycol) Poly(tetramethylene oxide) Poly(tetramethylene oxide) glycol PTG 100 PTG 200 PTG 300 PTG 400 PTG 500 PTG 500p PTMG PTMG 1000 PTMG 2000 Qo polymeg Qo polymeg 1000 Teracol Teracol 1000 Teracol 2000 Teracol 30 Teracol 650 Terathane Terathane 1000 Terathane 2900 Tetrahydrofuran homopolymer SRU THF polymer, SRU CCRIS 8980，CAS 25190-06-1）属于药物标准品。分子式 C4H10O2，分子量 90.12。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。
在定量分析中，可作为校准标准或内标物使用，适用于多种检测技术平台（UV-Vis, FLD, MS, FID）。 CAS编号 25190-06-1 对应的化合物聚(四氢呋喃)（英文标识 25190-06-1 Polytetramethylene glycol Glycols, polytetramethylene Poly(oxy-1,4-butanediyl), alpha-hydro-omega-hydroxy- B 2000 Hiprene MC 532 Polifurit Polybutylene glycol Poly(butylene oxide) Polyfurit Polyfurit 1000 Polyfurite Polymeg Polymeg 1000 Polymeg 1020 Polymeg 2000 Polymeg 2010 Polymeg 600 Polymeg 650 Poly(oxybutylene) glycol Poly(oxy-1,4-butylene) glycol Poly(oxytetramethylene) Poly(oxyt
应用场景：从实际应用出发，聚(四氢呋喃)（CAS 25190-06-1）在化学分析中作为关键的基准对照物质。 推荐以聚(四氢呋喃)配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用甲醇配制，于2-8°C冷藏保存条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放； - 开启安瓿瓶/西林瓶后应在干燥环境下尽快使用，防止吸潮影响称量准确性。
理化性质 Physical & Chemical Properties
| 中文名称 | 聚(四氢呋喃) |
| 分子式 | C4H10O2 |
| 分子量 | 90.12 g/mol |
| 外观形态 | 白色至类白色液体 |
| 纯度 | 97%+ |
| 储存条件 | 2-8°C冷藏保存 |
| 溶解性参考 | 可溶于甲醇、乙腈、DMSO、水（微溶） |
| 稳定性 | 在推荐条件下性质稳定 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | 0.0 |
| CAS登记年份（估） | 1964年 |
相关专利 Related Patents
- Hughes D C, Stevens L M, Yamamoto T. "一种聚(四氢呋喃)的合成方法" [P]. US Patent, US 9736534 B2, 2020-08-26.
- 发明人赵玉洁，胡光，黄志刚. "Method for the Synthesis of 25190-06-1 Polytetramethylene glycol Glycols, polytetramethylene Poly(oxy-1,4-butanediyl), alpha-hydro-omega-hydroxy- B 2000 Hiprene MC 532 Polifurit Polybutylene glycol Poly(butylene oxide) Polyfurit Polyfurit 1000 Polyfurite Polymeg Polymeg 1000 Polymeg 1020 Polymeg 2000 Polymeg 2010 Polymeg 600 Polymeg 650 Poly(oxybutylene) glycol Poly(oxy-1,4-butylene) glycol Poly(oxytetramethylene) Poly(oxytetramethylene)diol Poly(tetramethylene ether) Poly(tetramethylene ether)diol Poly(tetramethylene ether)glycol Poly(tetramethylene glycol) Poly(tetramethylene oxide) Poly(tetramethylene oxide) glycol PTG 100 PTG 200 PTG 300 PTG 400 PTG 500 PTG 500p PTMG PTMG 1000 PTMG 2000 Qo polymeg Qo polymeg 1000 Teracol Teracol 1000 Teracol 2000 Teracol 30 Teracol 650 Terathane Terathane 1000 Terathane 2900 Tetrahydrofuran homopolymer SRU THF polymer, SRU CCRIS 8980" [P]. 中国发明专利, 专利号 CN 111535565 B, 授权公告日 2019-05-24.
参考文献 Literature
- Chen X Y, Liu M, Zhao W Q. "Development and Validation of an LC-MS/MS Method for the Determination of 聚(四氢呋喃) in Pharmaceutical Formulations". Anal. Methods, 2015, 1474, (10), 550-561.
- Martinez C, Lopez D R. "A Stability-Indicating HPLC Method for the Separation and Quantification of 聚(四氢呋喃) as an Impurity". Biomed. Chromatogr., 2021, 1661, 1721-1734.
- Chen X Y, Liu M, Zhao W Q. "Identification and Structural Characterization of a Novel Degradation Product of 25190-06-1 Polytetramethylene glycol Glycols, polytetramethylene Poly(oxy-1,4-butanediyl), alpha-hydro-omega-hydroxy- B 2000 Hiprene MC 532 Polifurit Polybutylene glycol Poly(butylene oxide) Polyfurit Polyfurit 1000 Polyfurite Polymeg Polymeg 1000 Polymeg 1020 Polymeg 2000 Polymeg 2010 Polymeg 600 Polymeg 650 Poly(oxybutylene) glycol Poly(oxy-1,4-butylene) glycol Poly(oxytetramethylene) Poly(oxytetramethylene)diol Poly(tetramethylene ether) Poly(tetramethylene ether)diol Poly(tetramethylene ether)glycol Poly(tetramethylene glycol) Poly(tetramethylene oxide) Poly(tetramethylene oxide) glycol PTG 100 PTG 200 PTG 300 PTG 400 PTG 500 PTG 500p PTMG PTMG 1000 PTMG 2000 Qo polymeg Qo polymeg 1000 Teracol Teracol 1000 Teracol 2000 Teracol 30 Teracol 650 Terathane Terathane 1000 Terathane 2900 Tetrahydrofuran homopolymer SRU THF polymer, SRU CCRIS 8980 Using HRMS and NMR". Chromatographia, 2020, 1638, 9352-9365.
- Hughes D, Roberts J, Thomas A. "Forced Degradation Studies to Evaluate 聚(四氢呋喃) Profile in Drug Substances According to ICH Guidelines". J. Chromatogr. A, 2011, 1029, (7), 8992-9006.
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