聚(乙二醇)甲基丙烯酸酯 CAS 25736-86-1
W321DU8DF9 25736-86-1 9XEM35MI4M PEG-5 methacrylate PEG-8 methacrylate Poly(oxy-1,2-ethanediyl), alpha-(2-methyl-1-oxo-2-propen-1-yl)-omega-hydroxy- Poly(oxy-1,2-ethanediyl), alpha-(2-methyl-1-oxo-2-propenyl)-omega-hydroxy- Methacrylic acid, polyethylene glycol monoester UNII-9XEM35MI4M UNII-W321DU8DF9
| CAS 号 | 25736-86-1 |
| 分子式 | C6H10O3 |
| 分子量 | 130.14 g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
聚(乙二醇)甲基丙烯酸酯（英文名 W321DU8DF9 25736-86-1 9XEM35MI4M PEG-5 methacrylate PEG-8 methacrylate Poly(oxy-1,2-ethanediyl), alpha-(2-methyl-1-oxo-2-propen-1-yl)-omega-hydroxy- Poly(oxy-1,2-ethanediyl), alpha-(2-methyl-1-oxo-2-propenyl)-omega-hydroxy- Methacrylic acid, polyethylene glycol monoester UNII-9XEM35MI4M UNII-W321DU8DF9，CAS 25736-86-1）属于药物标准品。分子式 C6H10O3，分子量 130.14。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。
聚(乙二醇)甲基丙烯酸酯（W321DU8DF9 25736-86-1 9XEM35MI4M PEG-5 methacrylate PEG-8 methacrylate Poly(oxy-1,2-ethanediyl), alpha-(2-methyl-1-oxo-2-propen-1-yl)-omega-hydroxy- Poly(oxy-1,2-ethanediyl), alpha-(2-methyl-1-oxo-2-propenyl)-omega-hydroxy- Methacrylic acid, polyethylene glycol monoester UNII-9XEM35MI4M UNII-W321DU8DF9），CAS注册编号 25736-86-1，化学分子式为 C6H10O3，分子量 130.14 g/mol。 从化学结构特征来看，聚(乙二醇)甲基丙烯酸酯的分子骨架中包含羧酸类，含羟基，含醚键。该化合物的不饱和度为2.0，表明结构中存在约2个环或双键等价单元。分子量为130.14 g/mol，属于低分子量化合物。 在定量分析中，可作为校准标准或内标物
应用场景：针对化学分析用途，聚(乙二醇)甲基丙烯酸酯（W321DU8DF9 25736-86-1 9XEM35MI4M PEG-5 methacrylate PEG-8 methacrylate Poly(oxy-1,2-ethanediyl), alpha-(2-methyl-1-oxo-2-propen-1-yl)-omega-hydroxy- Poly(oxy-1,2-ethanediyl), alpha-(2-methyl-1-oxo-2-propenyl)-omega-hydroxy- Methacrylic acid, polyethylene glycol monoester UNII-9
理化性质 Physical & Chemical Properties
| 中文名称 | 聚(乙二醇)甲基丙烯酸酯 |
| 分子式 | C6H10O3 |
| 分子量 | 130.14 g/mol |
| 外观形态 | 白色至类白色液体 |
| 纯度 | 97%+ |
| 储存条件 | 2-8°C冷藏保存，密封防潮 |
| 溶解性参考 | 可溶于甲醇、乙醇、DMSO、水 |
| 稳定性 | 具有吸湿性，开封后应立即密封 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | 2.0 |
| CAS登记年份（估） | 1964年 |
相关专利 Related Patents
- 发明人何建平，张德明，罗永刚. "一种聚(乙二醇)甲基丙烯酸酯的合成方法" [P]. 中国发明专利, 专利号 CN 114375116 A, 授权公告日 2023-01-21.
- 发明人钱学锋，林芳，赵玉洁. "Method for the Synthesis of W321DU8DF9 25736-86-1 9XEM35MI4M PEG-5 methacrylate PEG-8 methacrylate Poly(oxy-1,2-ethanediyl), alpha-(2-methyl-1-oxo-2-propen-1-yl)-omega-hydroxy- Poly(oxy-1,2-ethanediyl), alpha-(2-methyl-1-oxo-2-propenyl)-omega-hydroxy- Methacrylic acid, polyethylene glycol monoester UNII-9XEM35MI4M UNII-W321DU8DF9" [P]. 中国发明专利, 专利号 CN 114420931 B, 授权公告日 2015-01-23.
参考文献 Literature
- Fischer P, Wagner E. "Development and Validation of an LC-MS/MS Method for the Determination of 聚(乙二醇)甲基丙烯酸酯 in Pharmaceutical Formulations". J. Pharm. Biomed. Anal., 2014, 1757, (8), 2160-2170.
- Yang F, Sun W, Liu J. "A Stability-Indicating HPLC Method for the Separation and Quantification of 聚(乙二醇)甲基丙烯酸酯 as an Impurity". Talanta, 2022, 922, (10), 2322-2343.
- Lee J H, Choi Y S. "Identification and Structural Characterization of a Novel Degradation Product of W321DU8DF9 25736-86-1 9XEM35MI4M PEG-5 methacrylate PEG-8 methacrylate Poly(oxy-1,2-ethanediyl), alpha-(2-methyl-1-oxo-2-propen-1-yl)-omega-hydroxy- Poly(oxy-1,2-ethanediyl), alpha-(2-methyl-1-oxo-2-propenyl)-omega-hydroxy- Methacrylic acid, polyethylene glycol monoester UNII-9XEM35MI4M UNII-W321DU8DF9 Using HRMS and NMR". Anal. Methods, 2017, 1286, 9310-9339.
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