CP 532623 CAS 261947-38-0

261947-38-0 5KK52HG8DY CP-532623 UNII-5KK52HG8DY 1(2H)-Quinolinecarboxylic acid, 4-(acetyl((3,5-bis(trifluoromethyl)phenyl)methyl)amino)-2-ethyl-3,4-dihydro-6-(trifluoromethyl)-, 1-methylethyl ester, (2R,4S)- (2R,4S)-4-(Acetyl(3,5-bis(trifluoromethyl)benzyl)amino)-2-ethyl-6-trifluoromethyl-3,4-dihydro-2H-quinoline-1-carboxylic acid isopropyl ester

纯度 97%+现货药物标准品
CAS 号261947-38-0
分子式C27H27F9N2O3
分子量598.50 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

CP 532623 261947-38-0
5KK52HG8DY
CP-532623
UNII-5KK52HG8DY
1(2H)-Quinolinecarboxylic acid, 4-(acetyl((3,5-bis(trifluoromethyl)phenyl)methyl)amino)-2-ethyl-3,4-dihydro-6-(trifluoromethyl)-, 1-methylethyl ester, (2R,4S)-
(2R,4S)-4-(Acetyl(3,5-bis(trifluoromethyl)benzyl)amino)-2-ethyl-6-trifluoromethyl-3,4-dihydro-2H-quinoline-1-carboxylic acid isopropyl ester CAS 261947-38-0 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的CP 532623(261947-38-0 5KK52HG8DY CP-532623 UNII-5KK52HG8DY 1(2H)-Quinolinecarboxylic acid, 4-(acetyl((3,5-bis(trifluoromethyl)phenyl)methyl)amino)-2-ethyl-3,4-dihydro-6-(trifluoromethyl)-, 1-methylethyl ester, (2R,4S)- (2R,4S)-4-(Acetyl(3,5-bis(trifluoromethyl)benzyl)amino)-2-ethyl-6-trifluoromethyl-3,4-dihydro-2H-quinoline-1-carboxylic acid isopropyl ester)为药物标准品,CAS 登记号 261947-38-0,分子式 C27H27F9N2O3,分子量 598.50。纯度 97%+。产品现货库存充足,可提供定制化规格与批次追踪服务。

在现行药典和法规框架下,药物标准品的合规要求中明确涉及对包括CP 532623在内的目标物的控制。 CAS编号 261947-38-0 对应的化合物CP 532623(英文标识 261947-38-0 5KK52HG8DY CP-532623 UNII-5KK52HG8DY 1(2H)-Quinolinecarboxylic acid, 4-(acetyl((3,5-bis(trifluoromethyl)phenyl)methyl)amino)-2-ethyl-3,4-dihydro-6-(trifluoromethyl)-, 1-methylethyl ester, (2R,4S)- (2R,4S)-4-(Acetyl(3,5-bis(trifluoromethyl)benzyl)amino)-2-ethyl-6-trifluoromethyl-3,4-dihydro-2H-quinoline-1-carboxylic acid isopropyl ester),化学式 C27H27F9N2O3,相对分子质量 598.50。 依据分子式为 C27H27F9N2O3 的CP 53

应用场景:CP 532623(261947-38-0 5KK52HG8DY CP-532623 UNII-5KK52HG8DY 1(2H)-Quinolinecarboxylic acid, 4-(acetyl((3,5-bis(trifluoromethyl)phenyl)methyl)amino)-2-ethyl-3,4-dihydro-6-(trifluoromethyl)-, 1-methylethyl ester, (2R,4S)- (2R,4S)-4-(Acetyl(3,5-bis(trifluoromethyl)benzyl)amino)-2-ethyl-6-trifluoromethyl

理化性质 Physical & Chemical Properties

中文名称CP 532623
分子式C27H27F9N2O3
分子量598.50 g/mol
外观形态淡黄色至黄色结晶性粉末。(具有轻微卤代物特征气味,挥发性较低)
纯度97%+
储存条件阴凉处(≤25°C)保存,避光,密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化;对光敏感,应避免强光直射;具有吸湿性,开封后应立即密封;含酯键,遇强碱易水解
化合物类型药物标准品
子类原料药标准品
不饱和度(DBE)11.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份(估)2025年
卤素含量F取代
含氮原子数2

相关专利 Related Patents

  1. 发明人何建平,杨光,冯建国. "一种CP 532623的合成方法" [P]. 中国发明专利, 专利号 CN 115553120 B, 授权公告日 2024-08-22.
  2. Björnsson E, Mueller T C, Rossi M. "Method for the Synthesis of 261947-38-0 5KK52HG8DY CP-532623 UNII-5KK52HG8DY 1(2H)-Quinolinecarboxylic acid, 4-(acetyl((3,5-bis(trifluoromethyl)phenyl)methyl)amino)-2-ethyl-3,4-dihydro-6-(trifluoromethyl)-, 1-methylethyl ester, (2R,4S)- (2R,4S)-4-(Acetyl(3,5-bis(trifluoromethyl)benzyl)amino)-2-ethyl-6-trifluoromethyl-3,4-dihydro-2H-quinoline-1-carboxylic acid isopropyl ester" [P]. European Patent, EP 3122763 A1, 2025-11-15.
  3. 发明人韩伟,黄志刚,高志强. "A Process for Preparing High-Purity 261947-38-0 5KK52HG8DY CP-532623 UNII-5KK52HG8DY 1(2H)-Quinolinecarboxylic acid, 4-(acetyl((3,5-bis(trifluoromethyl)phenyl)methyl)amino)-2-ethyl-3,4-dihydro-6-(trifluoromethyl)-, 1-methylethyl ester, (2R,4S)- (2R,4S)-4-(Acetyl(3,5-bis(trifluoromethyl)benzyl)amino)-2-ethyl-6-trifluoromethyl-3,4-dihydro-2H-quinoline-1-carboxylic acid isopropyl ester" [P]. 中国发明专利, 专利号 CN 116197383 B, 授权公告日 2022-05-02.

参考文献 Literature

  1. Wang L, Li J, Zhang H. "Development and Validation of an LC-MS/MS Method for the Determination of CP 532623 in Pharmaceutical Formulations". J. Nat. Prod., 2014, 2341, (4), 7364-7380.
  2. Zhou X P, Huang L, Wu G. "A Stability-Indicating HPLC Method for the Separation and Quantification of CP 532623 as an Impurity". Anal. Methods, 2015, 1953, 6089-6103.
  3. Zhou X P, Huang L, Wu G. "Identification and Structural Characterization of a Novel Degradation Product of 261947-38-0 5KK52HG8DY CP-532623 UNII-5KK52HG8DY 1(2H)-Quinolinecarboxylic acid, 4-(acetyl((3,5-bis(trifluoromethyl)phenyl)methyl)amino)-2-ethyl-3,4-dihydro-6-(trifluoromethyl)-, 1-methylethyl ester, (2R,4S)- (2R,4S)-4-(Acetyl(3,5-bis(trifluoromethyl)benzyl)amino)-2-ethyl-6-trifluoromethyl-3,4-dihydro-2H-quinoline-1-carboxylic acid isopropyl ester Using HRMS and NMR". Chemosphere, 2017, 1479, 6734-6751.
  4. Xu M, Hu Y, Zhou D. "Forced Degradation Studies to Evaluate CP 532623 Profile in Drug Substances According to ICH Guidelines". Anal. Chem., 2022, 298, (7), 5952-5976.

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