依替膦酸 CAS 2809-21-4

M2F465ROXU 2809-21-4 Etidronic acid Etidronic acid [USAN:INN:BAN] 1-Hydroxy-1,1-diphosphonoethane (1-Hydroxyethylidene)bisphosphonic acid Phosphonic acid, (1-hydroxyethylidene)bis- Phosphonic acid, (1-hydroxyethylidene)di- Phosphonic acid, P,P'-(1-hydroxyethylidene)bis- 1000SL 0-02-00-00171 (Beilstein Handbook Reference) Acide etidronique [INN-French] Acido etidronico [INN-Spanish] Acidum etidronicum [INN-Latin] BRN 1789291 Dequest Z 010 Dequest 2010 Dequest 2015 Diphosphonate (base) EHDP EINECS 220-552-8 Ethane-1-hydroxy-1,1-diphosphonate Ethane-1-hydroxy-1,1-diphosphonic acid 1,1,1-Ethanetriol diphosphonate Ferrofos 510 HEDP HSDB 5898 1-Hydroxyethane-1,1-bisphosphonic acid 1-Hydroxyethane-1,1-diphosphonate Hydroxyethanediphosphonic acid 1-Hydroxyethanediphosphonic acid Hydroxyethane-1,1-diphosphonic acid 1-Hydroxyethane-1,1-diphosphonic acid (1-Hydroxyethylene)diphosphonic acid 1-Hydroxyethylidene-1,1-biphosphonate 1-Hydroxyethylidene-1,1-bisphosphonate (1-Hydroxyethylidene)bis(phosphonic acid) (1-Hydroxyethylidene)diphoshonic acid (Hydroxyethylidene)diphosphonic acid (1-Hydroxyethylidene)diphosphonic acid 1-Hydroxyethylidene-1,1-diphosphonic acid NSC 227995 Oxyethylidenediphosphonic acid Phosphonic acid, 1-hydroxy-1,1-ethanediyl ester Turpinal SL RP 61 Acetodiphosphonic acid Etidronsaeure Acide etidronique Acido etidronico Acidum etidronicum Etidronate UNII-M2F465ROXU EC 220-552-8

纯度 97%+现货药物标准品
CAS 号2809-21-4
分子式C2H8O7P2
分子量206.03 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

依替膦酸 M2F465ROXU 2809-21-4 Etidronic acid Etidronic acid [USAN:INN:BAN] 1-Hydroxy-1,1-diphosphonoethane (1-Hydroxyethylidene)bisphosphonic acid Phosphonic acid, (1-hydroxyethylidene)bis- Phosphonic acid, (1-hydroxyethylidene)di- Phosphonic acid, P,P'-(1-hydroxyethylidene)bis- 1000SL 0-02-00-00171 (Beilstein Handbook Reference) Acide etidronique [INN-French] Acido etidronico [INN-Spanish] Acidum etidronicum [INN-Latin] BRN 1789291 Dequest Z 010 Dequest 2010 Dequest 2015 Diphosphonate (base) EHDP EINECS 220-552-8 Ethane-1-hydroxy-1,1-diphosphonate Ethane-1-hydroxy-1,1-diphosphonic acid 1,1,1-Ethanetriol diphosphonate Ferrofos 510 HEDP HSDB 5898 1-Hydroxyethane-1,1-bisphosphonic acid 1-Hydroxyethane-1,1-diphosphonate Hydroxyethanediphosphonic acid 1-Hydroxyethanediphosphonic acid Hydroxyethane-1,1-diphosphonic acid 1-Hydroxyethane-1,1-diphosphonic acid (1-Hydroxyethylene)diphosphonic acid 1-Hydroxyethylidene-1,1-biphosphonate 1-Hydroxyethylidene-1,1-bisphosphonate (1-Hydroxyethylidene)bis(phosphonic acid) (1-Hydroxyethylidene)diphoshonic acid (Hydroxyethylidene)diphosphonic acid (1-Hydroxyethylidene)diphosphonic acid 1-Hydroxyethylidene-1,1-diphosphonic acid NSC 227995 Oxyethylidenediphosphonic acid Phosphonic acid, 1-hydroxy-1,1-ethanediyl ester Turpinal SL RP 61 Acetodiphosphonic acid Etidronsaeure Acide etidronique Acido etidronico Acidum etidronicum Etidronate UNII-M2F465ROXU EC 220-552-8 CAS 2809-21-4 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的依替膦酸（M2F465ROXU 2809-21-4 Etidronic acid Etidronic acid [USAN:INN:BAN] 1-Hydroxy-1,1-diphosphonoethane (1-Hydroxyethylidene)bisphosphonic acid Phosphonic acid, (1-hydroxyethylidene)bis- Phosphonic acid, (1-hydroxyethylidene)di- Phosphonic acid, P,P'-(1-hydroxyethylidene)bis- 1000SL 0-02-00-00171 (Beilstein Handbook Reference) Acide etidronique [INN-French] Acido etidronico [INN-Spanish] Acidum etidronicum [INN-Latin] BRN 1789291 Dequest Z 010 Dequest 2010 Dequest 2015 Diphosphonate (base) EHDP EINECS 220-552-8 Ethane-1-hydroxy-1,1-diphosphonate Ethane-1-hydroxy-1,1-diphosphonic acid 1,1,1-Ethanetriol diphosphonate Ferrofos 510 HEDP HSDB 5898 1-Hydroxyethane-1,1-bisphosphonic acid 1-Hydroxyethane-1,1-diphosphonate Hydroxyethanediphosphonic acid 1-Hydroxyethanediphosphonic acid Hydroxyethane-1,1-diphosphonic acid 1-Hydroxyethane-1,1-diphosphonic acid (1-Hydroxyethylene)diphosphonic acid 1-Hydroxyethylidene-1,1-biphosphonate 1-Hydroxyethylidene-1,1-bisphosphonate (1-Hydroxyethylidene)bis(phosphonic acid) (1-Hydroxyethylidene)diphoshonic acid (Hydroxyethylidene)diphosphonic acid (1-Hydroxyethylidene)diphosphonic acid 1-Hydroxyethylidene-1,1-diphosphonic acid NSC 227995 Oxyethylidenediphosphonic acid Phosphonic acid, 1-hydroxy-1,1-ethanediyl ester Turpinal SL RP 61 Acetodiphosphonic acid Etidronsaeure Acide etidronique Acido etidronico Acidum etidronicum Etidronate UNII-M2F465ROXU EC 220-552-8）为药物标准品，CAS 登记号 2809-21-4，分子式 C2H8O7P2，分子量 206.03。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

从化学结构特征来看，依替膦酸的分子骨架中包含含磷酸酯基，羧酸类，含醚键。该化合物的不饱和度为-1.0，表明结构中存在约0个环或双键等价单元。分子量为206.03 g/mol，属于中等分子量化合物。 依替膦酸（M2F465ROXU 2809-21-4 Etidronic acid Etidronic acid USAN:INN:BAN 1-Hydroxy-1,1-diphosphonoethane (1-Hydroxyethylidene)bisphosphonic acid Phosphonic acid, (1-hydroxyethylidene)bis- Phosphonic acid, (1-hydroxyethylidene)di- Phosphonic acid, P,P'-(1-hydroxyethylidene)bis- 1000SL 0-02-00-00171 (Beilstein Handbook Reference) Acide etidronique INN-French Acido etidronico INN-Spanish Acidum eti

应用场景：依替膦酸（M2F465ROXU 2809-21-4 Etidronic acid Etidronic acid USAN:INN:BAN 1-Hydroxy-1,1-diphosphonoethane (1-Hydroxyethylidene)bisphosphonic acid Phosphonic acid, (1-hydroxyethylidene)bis- Phosphonic acid, (1-hydroxyethylidene)di- Phosphonic acid, P,P'-(1-hydroxyethylidene)bis- 1000SL 0-02-00-00171 (Be

理化性质 Physical & Chemical Properties

中文名称依替膦酸
分子式C2H8O7P2
分子量206.03 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件阴凉处（≤25°C）保存，密封防潮
溶解性参考可溶于甲醇、乙醇、DMSO、水
稳定性具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）-1.0
CAS登记年份（估）1957年

相关专利 Related Patents

  1. 发明人王建平，钱学锋，冯建国. "一种依替膦酸的合成方法" [P]. 中国发明专利, 专利号 CN 112894303 B, 授权公告日 2019-01-24.
  2. Davis P L, Mueller T, Klinger H. "Method for the Synthesis of M2F465ROXU 2809-21-4 Etidronic acid Etidronic acid [USAN:INN:BAN] 1-Hydroxy-1,1-diphosphonoethane (1-Hydroxyethylidene)bisphosphonic acid Phosphonic acid, (1-hydroxyethylidene)bis- Phosphonic acid, (1-hydroxyethylidene)di- Phosphonic acid, P,P'-(1-hydroxyethylidene)bis- 1000SL 0-02-00-00171 (Beilstein Handbook Reference) Acide etidronique [INN-French] Acido etidronico [INN-Spanish] Acidum etidronicum [INN-Latin] BRN 1789291 Dequest Z 010 Dequest 2010 Dequest 2015 Diphosphonate (base) EHDP EINECS 220-552-8 Ethane-1-hydroxy-1,1-diphosphonate Ethane-1-hydroxy-1,1-diphosphonic acid 1,1,1-Ethanetriol diphosphonate Ferrofos 510 HEDP HSDB 5898 1-Hydroxyethane-1,1-bisphosphonic acid 1-Hydroxyethane-1,1-diphosphonate Hydroxyethanediphosphonic acid 1-Hydroxyethanediphosphonic acid Hydroxyethane-1,1-diphosphonic acid 1-Hydroxyethane-1,1-diphosphonic acid (1-Hydroxyethylene)diphosphonic acid 1-Hydroxyethylidene-1,1-biphosphonate 1-Hydroxyethylidene-1,1-bisphosphonate (1-Hydroxyethylidene)bis(phosphonic acid) (1-Hydroxyethylidene)diphoshonic acid (Hydroxyethylidene)diphosphonic acid (1-Hydroxyethylidene)diphosphonic acid 1-Hydroxyethylidene-1,1-diphosphonic acid NSC 227995 Oxyethylidenediphosphonic acid Phosphonic acid, 1-hydroxy-1,1-ethanediyl ester Turpinal SL RP 61 Acetodiphosphonic acid Etidronsaeure Acide etidronique Acido etidronico Acidum etidronicum Etidronate UNII-M2F465ROXU EC 220-552-8" [P]. US Patent, US 11325458 B2, 2022-06-03.

参考文献 Literature

  1. Fischer P, Wagner E. "Development and Validation of an LC-MS/MS Method for the Determination of 依替膦酸 in Pharmaceutical Formulations". J. Sep. Sci., 2023, 2133, (9), 2863-2889.
  2. Lee J H, Choi Y S. "A Stability-Indicating HPLC Method for the Separation and Quantification of 依替膦酸 as an Impurity". J. Nat. Prod., 2011, 1405, (2), 6457-6482.

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