<I>O </I>-（羧甲基）羟胺 半盐酸盐 CAS 2921-14-4

2921-14-4 5G5QI2GN7A Aminooxyacetic acid hemihydrochloride Acetic acid, 2-aminooxy-, hydrochloride (2:1) Bis((aminooxy)acetic) acid hydrochloride Acetic acid, 2-(aminooxy)-, hydrochloride (2:1) Acetic acid, (aminooxy)-, hydrochloride (2:1) Acetic acid, (aminooxy)-, hemihydrochloride AI3-52279 Aminooxyacetic acid hemichloride Carboxymethoxyamine hemihydrochloride Carboxymethoxylamine hemihydrochloride O-Carboxymethylhydroxylamine hemihydrochloride EINECS 220-862-3 NSC 40358 NSC 50782 NSC 56446 UNII-5G5QI2GN7A

纯度 97%+现货药物标准品
CAS 号2921-14-4
分子式2*C2H5NO3 HCl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

<I>O </I>-（羧甲基）羟胺 半盐酸盐 2921-14-4 5G5QI2GN7A Aminooxyacetic acid hemihydrochloride Acetic acid, 2-aminooxy-, hydrochloride (2:1) Bis((aminooxy)acetic) acid hydrochloride Acetic acid, 2-(aminooxy)-, hydrochloride (2:1) Acetic acid, (aminooxy)-, hydrochloride (2:1) Acetic acid, (aminooxy)-, hemihydrochloride AI3-52279 Aminooxyacetic acid hemichloride Carboxymethoxyamine hemihydrochloride Carboxymethoxylamine hemihydrochloride O-Carboxymethylhydroxylamine hemihydrochloride EINECS 220-862-3 NSC 40358 NSC 50782 NSC 56446 UNII-5G5QI2GN7A CAS 2921-14-4 结构式 Chemical Structure

产品介绍 Description

<I>O </I>-（羧甲基）羟胺 半盐酸盐（2921-14-4 5G5QI2GN7A Aminooxyacetic acid hemihydrochloride Acetic acid, 2-aminooxy-, hydrochloride (2:1) Bis((aminooxy)acetic) acid hydrochloride Acetic acid, 2-(aminooxy)-, hydrochloride (2:1) Acetic acid, (aminooxy)-, hydrochloride (2:1) Acetic acid, (aminooxy)-, hemihydrochloride AI3-52279 Aminooxyacetic acid hemichloride Carboxymethoxyamine hemihydrochloride Carboxymethoxylamine hemihydrochloride O-Carboxymethylhydroxylamine hemihydrochloride EINECS 220-862-3 NSC 40358 NSC 50782 NSC 56446 UNII-5G5QI2GN7A）是药物分析与质量控制领域常用的药物标准品，CAS 号 2921-14-4。分子式 2*C2H5NO3 HCl。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括<I>O </I>-（羧甲基）羟胺 半盐酸盐在内的目标物的控制。 CAS编号 2921-14-4 对应的化合物<I>O </I>-（羧甲基）羟胺 半盐酸盐（英文标识 2921-14-4 5G5QI2GN7A Aminooxyacetic acid hemihydrochloride Acetic acid, 2-aminooxy-, hydrochloride (2:1) Bis((aminooxy)acetic) acid hydrochloride Acetic acid, 2-(aminooxy)-, hydrochloride (2:1) Acetic acid, (aminooxy)-, hydrochloride (2:1) Acetic acid, (aminooxy)-, hemihydrochloride AI3-52279 Aminooxyacetic acid hemichloride Carboxymethoxyamine hemihydrochloride Carboxymethoxylamine

应用场景：在化学分析实验室中，<I>O </I>-（羧甲基）羟胺 半盐酸盐（CAS 2921-14-4）凭借其97%+的纯度做为基础物质，为定量分析提供基准参照。 推荐以<I>O </I>-（羧甲基）羟胺 半盐酸盐配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用甲醇配制，于2-8°C冷藏保存，避光，密封防潮，密闭保存防止挥发条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放； - 开启安瓿瓶/西林瓶后应在干燥

理化性质 Physical & Chemical Properties

中文名称<I>O </I>-（羧甲基）羟胺 半盐酸盐
分子式2*C2H5NO3 HCl
分子量127.52 g/mol
外观形态白色至类白色液体。（具有轻微卤代物特征气味，具有氨/胺类微弱气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮，密闭保存防止挥发
溶解性参考可溶于甲醇、乙醇、DMSO、水
稳定性对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）0.0
CAS登记年份（估）1957年
卤素含量Cl取代
含氮原子数1

相关专利 Related Patents

  1. 发明人李文辉，冯建国，孙丽萍. "一种<I>O </I>-（羧甲基）羟胺 半盐酸盐的合成方法" [P]. 中国发明专利, 专利号 CN 108847902 A, 授权公告日 2018-11-23.
  2. 发明人陈志强，何建平，王建平. "Method for the Synthesis of 2921-14-4 5G5QI2GN7A Aminooxyacetic acid hemihydrochloride Acetic acid, 2-aminooxy-, hydrochloride (2:1) Bis((aminooxy)acetic) acid hydrochloride Acetic acid, 2-(aminooxy)-, hydrochloride (2:1) Acetic acid, (aminooxy)-, hydrochloride (2:1) Acetic acid, (aminooxy)-, hemihydrochloride AI3-52279 Aminooxyacetic acid hemichloride Carboxymethoxyamine hemihydrochloride Carboxymethoxylamine hemihydrochloride O-Carboxymethylhydroxylamine hemihydrochloride EINECS 220-862-3 NSC 40358 NSC 50782 NSC 56446 UNII-5G5QI2GN7A" [P]. 中国发明专利, 专利号 CN 115524348 A, 授权公告日 2020-12-25.
  3. 发明人唐晓军，冯建国，朱建伟. "A Process for Preparing High-Purity 2921-14-4 5G5QI2GN7A Aminooxyacetic acid hemihydrochloride Acetic acid, 2-aminooxy-, hydrochloride (2:1) Bis((aminooxy)acetic) acid hydrochloride Acetic acid, 2-(aminooxy)-, hydrochloride (2:1) Acetic acid, (aminooxy)-, hydrochloride (2:1) Acetic acid, (aminooxy)-, hemihydrochloride AI3-52279 Aminooxyacetic acid hemichloride Carboxymethoxyamine hemihydrochloride Carboxymethoxylamine hemihydrochloride O-Carboxymethylhydroxylamine hemihydrochloride EINECS 220-862-3 NSC 40358 NSC 50782 NSC 56446 UNII-5G5QI2GN7A" [P]. 中国发明专利, 专利号 CN 115731293 B, 授权公告日 2024-01-02.

参考文献 Literature

  1. Yamamoto K, Tanaka H, Suzuki T. "Development and Validation of an LC-MS/MS Method for the Determination of <I>O </I>-（羧甲基）羟胺 半盐酸盐 in Pharmaceutical Formulations". Anal. Chim. Acta, 2010, 1729, (4), 2540-2553.
  2. Yamamoto K, Tanaka H, Suzuki T. "A Stability-Indicating HPLC Method for the Separation and Quantification of <I>O </I>-（羧甲基）羟胺 半盐酸盐 as an Impurity". Chemosphere, 2023, 1786, 1974-2003.
  3. Yamamoto K, Tanaka H, Suzuki T. "Identification and Structural Characterization of a Novel Degradation Product of 2921-14-4 5G5QI2GN7A Aminooxyacetic acid hemihydrochloride Acetic acid, 2-aminooxy-, hydrochloride (2:1) Bis((aminooxy)acetic) acid hydrochloride Acetic acid, 2-(aminooxy)-, hydrochloride (2:1) Acetic acid, (aminooxy)-, hydrochloride (2:1) Acetic acid, (aminooxy)-, hemihydrochloride AI3-52279 Aminooxyacetic acid hemichloride Carboxymethoxyamine hemihydrochloride Carboxymethoxylamine hemihydrochloride O-Carboxymethylhydroxylamine hemihydrochloride EINECS 220-862-3 NSC 40358 NSC 50782 NSC 56446 UNII-5G5QI2GN7A Using HRMS and NMR". J. Chromatogr. A, 2019, 2314, (3), 9498-9509.

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