2-萘基硼酸 CAS 32316-92-0
(2-NAPHTHALYL)BORONIC ACID (3-PHENYLAMINOCARBONYLPHENYL)BORONIC ACID 2-NAPHTAHALENEBORONIC ACID 2-NAPHTHALENEBORONIC ACID 2-NAPHTHALENEYLBORONIC ACID 2-NAPHTHYLBORONIC ACID 2-NAPHTHYLBORONIC CAID 2-Naphthalene boronic acid 3-(PHENYLCARBAMOYL)BENZENEBORONIC ACID 32316-92-0 AKOS BRN-0041 AS03292 NAPHTHALEN-2-YL-2-BORONIC ACID NAPHTHALEN-2-YL-BORANEDIOL NAPHTHALEN-2-YLBORONIC ACID NAPHTHALENE-2-BORONIC ACID NAPHTHALENYL-2-BORONIC ACID PARAGOS 520029 RARECHEM AH PB 0126
| CAS 号 | 32316-92-0 |
| 分子式 | C10H19BO2 |
| 分子量 | 182.07 g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
2-萘基硼酸（(2-NAPHTHALYL)BORONIC ACID (3-PHENYLAMINOCARBONYLPHENYL)BORONIC ACID 2-NAPHTAHALENEBORONIC ACID 2-NAPHTHALENEBORONIC ACID 2-NAPHTHALENEYLBORONIC ACID 2-NAPHTHYLBORONIC ACID 2-NAPHTHYLBORONIC CAID 2-Naphthalene boronic acid 3-(PHENYLCARBAMOYL)BENZENEBORONIC ACID 32316-92-0 AKOS BRN-0041 AS03292 NAPHTHALEN-2-YL-2-BORONIC ACID NAPHTHALEN-2-YL-BORANEDIOL NAPHTHALEN-2-YLBORONIC ACID NAPHTHALENE-2-BORONIC ACID NAPHTHALENYL-2-BORONIC ACID PARAGOS 520029 RARECHEM AH PB 0126，CAS 号 32316-92-0）是 CATO 佳途自主生产的药物标准品，分子式 C10H19BO2，分子量 182.07。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。
在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括2-萘基硼酸在内的目标物的控制。 化学式为 C10H19BO2 的2-萘基硼酸（(2-NAPHTHALYL)BORONIC ACID (3-PHENYLAMINOCARBONYLPHENYL)BORONIC ACID 2-NAPHTAHALENEBORONIC ACID 2-NAPHTHALENEBORONIC ACID 2-NAPHTHALENEYLBORONIC ACID 2-NAPHTHYLBORONIC ACID 2-NAPHTHYLBORONIC CAID 2-Naphthalene boronic acid 3-(PHENYLCARBAMOYL)BENZENEBORONIC ACID 32316-92-0 AKOS BRN-0041 AS03292 NAPHTHALEN-2-YL-2-BORONIC ACID NAPHTHALEN-2-YL-BORANEDIOL NAPHTHALEN-2-YLBORONIC ACID NAPHTHALENE-2-BORONIC ACID NAPHTHALENYL-2-BORONI
应用场景：在化学分析实验室中，2-萘基硼酸（CAS 32316-92-0）凭借其97%+的纯度做为基础物质，为定量分析提供基准参照。 推荐以2-萘基硼酸配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用乙腈为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用乙腈配制，于2-8°C冷藏保存条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放； - 开启安瓿瓶/西林瓶后应在干燥环境下尽快使用，防止吸潮影响称量准确性。
理化性质 Physical & Chemical Properties
| 中文名称 | 2-萘基硼酸 |
| 分子式 | C10H19BO2 |
| 分子量 | 182.07 g/mol |
| 外观形态 | 白色至类白色结晶性粉末 |
| 纯度 | 97%+ |
| 储存条件 | 2-8°C冷藏保存 |
| 溶解性参考 | 可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO |
| 稳定性 | 在推荐条件下性质稳定 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | 1.5 |
| CAS登记年份（估） | 1966年 |
相关专利 Related Patents
- Hughes D C, Stevens L M, Williams B T. "一种2-萘基硼酸的合成方法" [P]. US Patent, US 9729833 B2, 2023-05-09.
- 发明人陈志强，胡光，郭海燕. "Method for the Synthesis of (2-NAPHTHALYL)BORONIC ACID (3-PHENYLAMINOCARBONYLPHENYL)BORONIC ACID 2-NAPHTAHALENEBORONIC ACID 2-NAPHTHALENEBORONIC ACID 2-NAPHTHALENEYLBORONIC ACID 2-NAPHTHYLBORONIC ACID 2-NAPHTHYLBORONIC CAID 2-Naphthalene boronic acid 3-(PHENYLCARBAMOYL)BENZENEBORONIC ACID 32316-92-0 AKOS BRN-0041 AS03292 NAPHTHALEN-2-YL-2-BORONIC ACID NAPHTHALEN-2-YL-BORANEDIOL NAPHTHALEN-2-YLBORONIC ACID NAPHTHALENE-2-BORONIC ACID NAPHTHALENYL-2-BORONIC ACID PARAGOS 520029 RARECHEM AH PB 0126" [P]. 中国发明专利, 专利号 CN 110710113 A, 授权公告日 2019-11-25.
- 发明人杨光，唐晓军，徐明华. "A Process for Preparing High-Purity (2-NAPHTHALYL)BORONIC ACID (3-PHENYLAMINOCARBONYLPHENYL)BORONIC ACID 2-NAPHTAHALENEBORONIC ACID 2-NAPHTHALENEBORONIC ACID 2-NAPHTHALENEYLBORONIC ACID 2-NAPHTHYLBORONIC ACID 2-NAPHTHYLBORONIC CAID 2-Naphthalene boronic acid 3-(PHENYLCARBAMOYL)BENZENEBORONIC ACID 32316-92-0 AKOS BRN-0041 AS03292 NAPHTHALEN-2-YL-2-BORONIC ACID NAPHTHALEN-2-YL-BORANEDIOL NAPHTHALEN-2-YLBORONIC ACID NAPHTHALENE-2-BORONIC ACID NAPHTHALENYL-2-BORONIC ACID PARAGOS 520029 RARECHEM AH PB 0126" [P]. 中国发明专利, 专利号 CN 116323120 B, 授权公告日 2021-04-05.
参考文献 Literature
- Lee J H, Choi Y S. "Development and Validation of an LC-MS/MS Method for the Determination of 2-萘基硼酸 in Pharmaceutical Formulations". Biomed. Chromatogr., 2016, 1863, (4), 4310-4317.
- Brown R C, Davis S M. "A Stability-Indicating HPLC Method for the Separation and Quantification of 2-萘基硼酸 as an Impurity". Anal. Chim. Acta, 2011, 1677, (7), 86-110.
- Kumar A, Sharma P, Patel R S. "Identification and Structural Characterization of a Novel Degradation Product of (2-NAPHTHALYL)BORONIC ACID (3-PHENYLAMINOCARBONYLPHENYL)BORONIC ACID 2-NAPHTAHALENEBORONIC ACID 2-NAPHTHALENEBORONIC ACID 2-NAPHTHALENEYLBORONIC ACID 2-NAPHTHYLBORONIC ACID 2-NAPHTHYLBORONIC CAID 2-Naphthalene boronic acid 3-(PHENYLCARBAMOYL)BENZENEBORONIC ACID 32316-92-0 AKOS BRN-0041 AS03292 NAPHTHALEN-2-YL-2-BORONIC ACID NAPHTHALEN-2-YL-BORANEDIOL NAPHTHALEN-2-YLBORONIC ACID NAPHTHALENE-2-BORONIC ACID NAPHTHALENYL-2-BORONIC ACID PARAGOS 520029 RARECHEM AH PB 0126 Using HRMS and NMR". Talanta, 2014, 1309, (4), 4812-4827.
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