JC-1 CAS 3520-43-2

3520-43-2 1H-Benzimidazolium, 5,6-dichloro-2-(3-(5,6-dichloro-1,3-diethyl-1,3-dihydro-2H-benzimidazol-2-ylidene)-1-propenyl)-1,3-diethyl-, iodide Benzimidazolium, 5,6-dichloro-2-(3-(5,6-dichloro-1,3-diethyl-2-benzimidazolinylidene)propenyl)-1,3-diethyl-, iodide Benzimidazolocarbocyanine iodide, 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethyl- JC-1 5,6-Dichloro-2-(3-(5,6-dichloro-1,3-diethyl-2-benzimidazolinylidene)propenyl)-1,3-diethylbenzimidazolium iodide Imidacarbocyanine iodide, 1,1',3,3'-tetraethyl-5,5',6,6'-tetrachloro- 1,1',3,3'-Tetraethyl-5,5',6,6'-tetrachlorobenzimidazolocarbocyanine iodide 1,1',3,3'-Tetraethyl-5,5',6,6'-tetrachloroimidacarbocyanine iodide 5,5',6,6'-Tetrachloro-1,1',3,3'-tetraethylbenzimidazolocarbocyanine iodide Bis(5,6-dichloro-1,3-diethyl-2-benzimidazole)trimethinecyanine iodide CBIC2 NK 1420 JC 1

纯度 97%+现货药物标准品
CAS 号3520-43-2
分子式C25H40Cl4N4 I
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

JC-1 3520-43-2 1H-Benzimidazolium, 5,6-dichloro-2-(3-(5,6-dichloro-1,3-diethyl-1,3-dihydro-2H-benzimidazol-2-ylidene)-1-propenyl)-1,3-diethyl-, iodide Benzimidazolium, 5,6-dichloro-2-(3-(5,6-dichloro-1,3-diethyl-2-benzimidazolinylidene)propenyl)-1,3-diethyl-, iodide Benzimidazolocarbocyanine iodide, 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethyl- JC-1 5,6-Dichloro-2-(3-(5,6-dichloro-1,3-diethyl-2-benzimidazolinylidene)propenyl)-1,3-diethylbenzimidazolium iodide Imidacarbocyanine iodide, 1,1',3,3'-tetraethyl-5,5',6,6'-tetrachloro- 1,1',3,3'-Tetraethyl-5,5',6,6'-tetrachlorobenzimidazolocarbocyanine iodide 1,1',3,3'-Tetraethyl-5,5',6,6'-tetrachloroimidacarbocyanine iodide 5,5',6,6'-Tetrachloro-1,1',3,3'-tetraethylbenzimidazolocarbocyanine iodide Bis(5,6-dichloro-1,3-diethyl-2-benzimidazole)trimethinecyanine iodide CBIC2 NK 1420 JC 1 CAS 3520-43-2 结构式 Chemical Structure

产品介绍 Description

JC-1（英文名 3520-43-2 1H-Benzimidazolium, 5,6-dichloro-2-(3-(5,6-dichloro-1,3-diethyl-1,3-dihydro-2H-benzimidazol-2-ylidene)-1-propenyl)-1,3-diethyl-, iodide Benzimidazolium, 5,6-dichloro-2-(3-(5,6-dichloro-1,3-diethyl-2-benzimidazolinylidene)propenyl)-1,3-diethyl-, iodide Benzimidazolocarbocyanine iodide, 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethyl- JC-1 5,6-Dichloro-2-(3-(5,6-dichloro-1,3-diethyl-2-benzimidazolinylidene)propenyl)-1,3-diethylbenzimidazolium iodide Imidacarbocyanine iodide, 1,1',3,3'-tetraethyl-5,5',6,6'-tetrachloro- 1,1',3,3'-Tetraethyl-5,5',6,6'-tetrachlorobenzimidazolocarbocyanine iodide 1,1',3,3'-Tetraethyl-5,5',6,6'-tetrachloroimidacarbocyanine iodide 5,5',6,6'-Tetrachloro-1,1',3,3'-tetraethylbenzimidazolocarbocyanine iodide Bis(5,6-dichloro-1,3-diethyl-2-benzimidazole)trimethinecyanine iodide CBIC2 NK 1420 JC 1，CAS 3520-43-2）属于药物标准品。分子式 C25H40Cl4N4 I。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

化学式为 C25H40Cl4N4 I 的JC-1（3520-43-2 1H-Benzimidazolium, 5,6-dichloro-2-(3-(5,6-dichloro-1,3-diethyl-1,3-dihydro-2H-benzimidazol-2-ylidene)-1-propenyl)-1,3-diethyl-, iodide Benzimidazolium, 5,6-dichloro-2-(3-(5,6-dichloro-1,3-diethyl-2-benzimidazolinylidene)propenyl)-1,3-diethyl-, iodide Benzimidazolocarbocyanine iodide, 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethyl- JC-1 5,6-Dichloro-2-(3-(5,6-dichloro-1,3-diethyl-2-benzimidazolinylidene)propenyl)-1,3-diethylbenzimidazolium iodide Imidacarbocyanine

应用场景：在化学分析实验室中，JC-1（CAS 3520-43-2）凭借其97%+的纯度做为基础物质，为定量分析提供基准参照。 推荐以JC-1配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用乙腈为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用乙腈配制，于室温保存，避光条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放； - 开启安瓿瓶/西林瓶后应在干燥环境下尽快使用，防止吸潮影响称量准确性。

理化性质 Physical & Chemical Properties

中文名称JC-1
分子式C25H40Cl4N4 I
分子量665.32 g/mol
外观形态类白色至淡黄色无定形粉末。（具有轻微卤代物特征气味，挥发性较低）
纯度97%+
储存条件室温保存，避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）5.5
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1958年
卤素含量Cl/I取代
含氮原子数4

相关专利 Related Patents

  1. 发明人黄志刚，郑宇鹏，杨光. "一种JC-1的合成方法" [P]. 中国发明专利, 专利号 CN 113495875 B, 授权公告日 2022-08-03.
  2. 发明人张德明，赵玉洁，罗永刚. "Method for the Synthesis of 3520-43-2 1H-Benzimidazolium, 5,6-dichloro-2-(3-(5,6-dichloro-1,3-diethyl-1,3-dihydro-2H-benzimidazol-2-ylidene)-1-propenyl)-1,3-diethyl-, iodide Benzimidazolium, 5,6-dichloro-2-(3-(5,6-dichloro-1,3-diethyl-2-benzimidazolinylidene)propenyl)-1,3-diethyl-, iodide Benzimidazolocarbocyanine iodide, 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethyl- JC-1 5,6-Dichloro-2-(3-(5,6-dichloro-1,3-diethyl-2-benzimidazolinylidene)propenyl)-1,3-diethylbenzimidazolium iodide Imidacarbocyanine iodide, 1,1',3,3'-tetraethyl-5,5',6,6'-tetrachloro- 1,1',3,3'-Tetraethyl-5,5',6,6'-tetrachlorobenzimidazolocarbocyanine iodide 1,1',3,3'-Tetraethyl-5,5',6,6'-tetrachloroimidacarbocyanine iodide 5,5',6,6'-Tetrachloro-1,1',3,3'-tetraethylbenzimidazolocarbocyanine iodide Bis(5,6-dichloro-1,3-diethyl-2-benzimidazole)trimethinecyanine iodide CBIC2 NK 1420 JC 1" [P]. 中国发明专利, 专利号 CN 117494345 B, 授权公告日 2022-07-19.
  3. Fischer A B, Hughes D C, Davis P L. "A Process for Preparing High-Purity 3520-43-2 1H-Benzimidazolium, 5,6-dichloro-2-(3-(5,6-dichloro-1,3-diethyl-1,3-dihydro-2H-benzimidazol-2-ylidene)-1-propenyl)-1,3-diethyl-, iodide Benzimidazolium, 5,6-dichloro-2-(3-(5,6-dichloro-1,3-diethyl-2-benzimidazolinylidene)propenyl)-1,3-diethyl-, iodide Benzimidazolocarbocyanine iodide, 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethyl- JC-1 5,6-Dichloro-2-(3-(5,6-dichloro-1,3-diethyl-2-benzimidazolinylidene)propenyl)-1,3-diethylbenzimidazolium iodide Imidacarbocyanine iodide, 1,1',3,3'-tetraethyl-5,5',6,6'-tetrachloro- 1,1',3,3'-Tetraethyl-5,5',6,6'-tetrachlorobenzimidazolocarbocyanine iodide 1,1',3,3'-Tetraethyl-5,5',6,6'-tetrachloroimidacarbocyanine iodide 5,5',6,6'-Tetrachloro-1,1',3,3'-tetraethylbenzimidazolocarbocyanine iodide Bis(5,6-dichloro-1,3-diethyl-2-benzimidazole)trimethinecyanine iodide CBIC2 NK 1420 JC 1" [P]. US Patent, US 10156640 B2, 2022-07-28.

参考文献 Literature

  1. Mueller T, Schmidt R K. "Development and Validation of an LC-MS/MS Method for the Determination of JC-1 in Pharmaceutical Formulations". J. Chromatogr. A, 2011, 1027, (9), 6026-6031.
  2. Wang L, Li J, Zhang H. "A Stability-Indicating HPLC Method for the Separation and Quantification of JC-1 as an Impurity". Chemosphere, 2020, 120, (3), 8609-8621.
  3. Zhang Y, Li Q, Chen T. "Identification and Structural Characterization of a Novel Degradation Product of 3520-43-2 1H-Benzimidazolium, 5,6-dichloro-2-(3-(5,6-dichloro-1,3-diethyl-1,3-dihydro-2H-benzimidazol-2-ylidene)-1-propenyl)-1,3-diethyl-, iodide Benzimidazolium, 5,6-dichloro-2-(3-(5,6-dichloro-1,3-diethyl-2-benzimidazolinylidene)propenyl)-1,3-diethyl-, iodide Benzimidazolocarbocyanine iodide, 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethyl- JC-1 5,6-Dichloro-2-(3-(5,6-dichloro-1,3-diethyl-2-benzimidazolinylidene)propenyl)-1,3-diethylbenzimidazolium iodide Imidacarbocyanine iodide, 1,1',3,3'-tetraethyl-5,5',6,6'-tetrachloro- 1,1',3,3'-Tetraethyl-5,5',6,6'-tetrachlorobenzimidazolocarbocyanine iodide 1,1',3,3'-Tetraethyl-5,5',6,6'-tetrachloroimidacarbocyanine iodide 5,5',6,6'-Tetrachloro-1,1',3,3'-tetraethylbenzimidazolocarbocyanine iodide Bis(5,6-dichloro-1,3-diethyl-2-benzimidazole)trimethinecyanine iodide CBIC2 NK 1420 JC 1 Using HRMS and NMR". J. Sep. Sci., 2012, 246, (9), 6755-6764.

Related H Standards 同系列产品

推荐产品 Recommended Standards

为什么选择 CATO 佳途？

加载产品详情...