CAS 3625-07-8

69C642I19V 3625-07-8 Mebolazine Mebolazine [INN] 17beta-Hydroxy-2alpha,17-dimethyl-5alpha-androstan-3-one azine 17-beta-hydroxy-2-alpha,17-dimethyl-5-alpha-androstan-3-one azine Mebolazina [DCIT] Mebolazinum [INN-Latin] Mebulazina [INN-Spanish] Mebolazina Mebolazinum Mebulazina UNII-69C642I19V Dimethazine Dimetazin Roxilon

纯度 97%+现货药物标准品
CAS 号3625-07-8
分子式C42H68N2O2
分子量633.00 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

69C642I19V 3625-07-8 Mebolazine Mebolazine [INN] 17beta-Hydroxy-2alpha,17-dimethyl-5alpha-androstan-3-one azine 17-beta-hydroxy-2-alpha,17-dimethyl-5-alpha-androstan-3-one azine Mebolazina [DCIT] Mebolazinum [INN-Latin] Mebulazina [INN-Spanish] Mebolazina Mebolazinum Mebulazina UNII-69C642I19V Dimethazine Dimetazin Roxilon CAS 3625-07-8 结构式 Chemical Structure

产品介绍 Description

本产品为药物标准品（69C642I19V 3625-07-8 Mebolazine Mebolazine [INN] 17beta-Hydroxy-2alpha,17-dimethyl-5alpha-androstan-3-one azine 17-beta-hydroxy-2-alpha,17-dimethyl-5-alpha-androstan-3-one azine Mebolazina [DCIT] Mebolazinum [INN-Latin] Mebulazina [INN-Spanish] Mebolazina Mebolazinum Mebulazina UNII-69C642I19V Dimethazine Dimetazin Roxilon，CAS 3625-07-8），分子式 C42H68N2O2，分子量 633.00。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。

与同类药物标准品相比，的分子量为633.00 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 化学式为 C42H68N2O2 的（69C642I19V 3625-07-8 Mebolazine Mebolazine INN 17beta-Hydroxy-2alpha,17-dimethyl-5alpha-androstan-3-one azine 17-beta-hydroxy-2-alpha,17-dimethyl-5-alpha-androstan-3-one azine Mebolazina DCIT Mebolazinum INN-Latin Mebulazina INN-Spanish Mebolazina Mebolazinum Mebulazina UNII-69C642I19V Dimethazine Dimetazin Roxilon），其CAS登记号是 3625-07-8，分子量为 633.00 g/mol。 受分子结构中含氮杂环结构，酰胺类，含羟基，含醚键的影响，表现为淡黄色至黄色无定形粉末。其固体形态的物理化学属性——包

应用场景：（69C642I19V 3625-07-8 Mebolazine Mebolazine INN 17beta-Hydroxy-2alpha,17-dimethyl-5alpha-androstan-3-one azine 17-beta-hydroxy-2-alpha,17-dimethyl-5-alpha-androstan-3-one azine Mebolazina DCIT Mebolazinum INN-Latin Mebulazina INN-Spanish Mebolazina Mebolazinum Mebulazina UNII-69C642I19V Dime

理化性质 Physical & Chemical Properties

中文名称
分子式C42H68N2O2
分子量633.00 g/mol
外观形态淡黄色至黄色无定形粉末
纯度97%+
储存条件阴凉处（≤25°C）保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）10.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1958年
含氮原子数2

相关专利 Related Patents

  1. 发明人冯建国，杨光，郭海燕. "一种的合成方法" [P]. 中国发明专利, 专利号 CN 110110770 B, 授权公告日 2019-09-08.
  2. Nowak P, Kowalski A, Nielsen H. "Method for the Synthesis of 69C642I19V 3625-07-8 Mebolazine Mebolazine [INN] 17beta-Hydroxy-2alpha,17-dimethyl-5alpha-androstan-3-one azine 17-beta-hydroxy-2-alpha,17-dimethyl-5-alpha-androstan-3-one azine Mebolazina [DCIT] Mebolazinum [INN-Latin] Mebulazina [INN-Spanish] Mebolazina Mebolazinum Mebulazina UNII-69C642I19V Dimethazine Dimetazin Roxilon" [P]. European Patent, EP 3228055 A1, 2024-03-22.

参考文献 Literature

  1. Garcia M, Rodriguez P. "Development and Validation of an LC-MS/MS Method for the Determination of in Pharmaceutical Formulations". J. Agric. Food Chem., 2019, 1331, 4745-4774.
  2. Brown R C, Davis S M. "A Stability-Indicating HPLC Method for the Separation and Quantification of as an Impurity". Anal. Methods, 2016, 345, (12), 1210-1213.
  3. Smith J A, Johnson M B. "Identification and Structural Characterization of a Novel Degradation Product of 69C642I19V 3625-07-8 Mebolazine Mebolazine [INN] 17beta-Hydroxy-2alpha,17-dimethyl-5alpha-androstan-3-one azine 17-beta-hydroxy-2-alpha,17-dimethyl-5-alpha-androstan-3-one azine Mebolazina [DCIT] Mebolazinum [INN-Latin] Mebulazina [INN-Spanish] Mebolazina Mebolazinum Mebulazina UNII-69C642I19V Dimethazine Dimetazin Roxilon Using HRMS and NMR". Anal. Chim. Acta, 2023, 1733, 8818-8830.
  4. Yamamoto K, Tanaka H, Suzuki T. "Forced Degradation Studies to Evaluate Profile in Drug Substances According to ICH Guidelines". J. Chromatogr. A, 2022, 1707, 6305-6316.

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