4-[2-[4-[2-methoxy-5-[2-(1-methylquinolin-1-ium-4-yl)ethyl]phenoxy]phenyl]ethyl]-1-methyl-quinolin-1-ium diiodide CAS 365542-47-8

4-[2-[4-[2-methoxy-5-[2-(1-methylquinolin-1-ium-4-yl)ethyl]phenoxy]phenyl]ethyl]-1-methyl-quinolin-1-ium diiodide

纯度 97%+现货药物标准品
CAS 号365542-47-8
分子式C37H36N2O2 2*I
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

4-[2-[4-[2-methoxy-5-[2-(1-methylquinolin-1-ium-4-yl)ethyl]phenoxy]phenyl]ethyl]-1-methyl-quinolin-1-ium diiodide 4-[2-[4-[2-methoxy-5-[2-(1-methylquinolin-1-ium-4-yl)ethyl]phenoxy]phenyl]ethyl]-1-methyl-quinolin-1-ium diiodide CAS 365542-47-8 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的4-[2-[4-[2-methoxy-5-[2-(1-methylquinolin-1-ium-4-yl)ethyl]phenoxy]phenyl]ethyl]-1-methyl-quinolin-1-ium diiodide（4-[2-[4-[2-methoxy-5-[2-(1-methylquinolin-1-ium-4-yl)ethyl]phenoxy]phenyl]ethyl]-1-methyl-quinolin-1-ium diiodide）为药物标准品，CAS 登记号 365542-47-8，分子式 C37H36N2O2 2*I。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

作为认证标准物质（CRM），4-2-4-2-methoxy-5-2-(1-methylquinolin-1-ium-4-yl)ethylphenoxyphenylethyl-1-methyl-quinolin-1-ium diiodide满足CNAS-CL04（ISO/IEC 17025）对标准物质的计量溯源性要求。批间一致性通过控制图（Control Chart）进行持续监控，保证不同批次间量值的一致性。 CAS编号 365542-47-8 对应的化合物4-2-4-2-methoxy-5-2-(1-methylquinolin-1-ium-4-yl)ethylphenoxyphenylethyl-1-methyl-quinolin-1-ium diiodide（英文标识 4-2-4-2-methoxy-5-2-(1-methylquinolin-1-ium-4-yl)ethylphenoxyphenylethyl-1-methyl-quinolin-1-ium diiodide），化学式 C37H36N2O2 2I，

应用场景：在化学分析实验室中，4- 2- 4- 2-methoxy-5- 2-(1-methylquinolin-1-ium-4-yl)ethyl phenoxy phenyl ethyl -1-methyl-quinolin-1-ium diiodide（CAS 365542-47-8）凭借其97%+的纯度做为基础物质，为定量分析提供基准参照。 推荐以4- 2- 4- 2-methoxy-5- 2-(1-methylquinolin-1-ium-4-yl)ethyl phenoxy phenyl ethyl -1-methyl-quinolin-1-ium diiodide配制标准系列工作溶液，用于

理化性质 Physical & Chemical Properties

中文名称4-[2-[4-[2-methoxy-5-[2-(1-methylquinolin-1-ium-4-yl)ethyl]phenoxy]phenyl]ethyl]-1-methyl-quinolin-1-ium diiodide
分子式C37H36N2O2 2*I
分子量667.61 g/mol
外观形态淡黄色至黄色无定形粉末。（具有轻微卤代物特征气味）
纯度97%+
储存条件阴凉处（≤25°C）保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封；含酯键，遇强碱易水解
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）20.5
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）2025年
卤素含量I取代
含氮原子数2

相关专利 Related Patents

  1. 发明人李文辉，罗永刚，何建平. "一种4-[2-[4-[2-methoxy-5-[2-(1-methylquinolin-1-ium-4-yl)ethyl]phenoxy]phenyl]ethyl]-1-methyl-quinolin-1-ium diiodide的合成方法" [P]. 中国发明专利, 专利号 CN 117202128 A, 授权公告日 2018-04-24.
  2. 发明人韩伟，胡光，冯建国. "Method for the Synthesis of 4-[2-[4-[2-methoxy-5-[2-(1-methylquinolin-1-ium-4-yl)ethyl]phenoxy]phenyl]ethyl]-1-methyl-quinolin-1-ium diiodide" [P]. 中国发明专利, 专利号 CN 110201932 A, 授权公告日 2017-09-09.
  3. 发明人高志强，张德明，孙丽萍. "A Process for Preparing High-Purity 4-[2-[4-[2-methoxy-5-[2-(1-methylquinolin-1-ium-4-yl)ethyl]phenoxy]phenyl]ethyl]-1-methyl-quinolin-1-ium diiodide" [P]. 中国发明专利, 专利号 CN 114616942 B, 授权公告日 2015-12-08.

参考文献 Literature

  1. Mueller T, Schmidt R K. "Development and Validation of an LC-MS/MS Method for the Determination of 4-[2-[4-[2-methoxy-5-[2-(1-methylquinolin-1-ium-4-yl)ethyl]phenoxy]phenyl]ethyl]-1-methyl-quinolin-1-ium diiodide in Pharmaceutical Formulations". Anal. Chim. Acta, 2024, 1448, (2), 2026-2031.
  2. Smith J A, Johnson M B. "A Stability-Indicating HPLC Method for the Separation and Quantification of 4-[2-[4-[2-methoxy-5-[2-(1-methylquinolin-1-ium-4-yl)ethyl]phenoxy]phenyl]ethyl]-1-methyl-quinolin-1-ium diiodide as an Impurity". J. Nat. Prod., 2013, 1742, (10), 336-348.
  3. Xu M, Hu Y, Zhou D. "Identification and Structural Characterization of a Novel Degradation Product of 4-[2-[4-[2-methoxy-5-[2-(1-methylquinolin-1-ium-4-yl)ethyl]phenoxy]phenyl]ethyl]-1-methyl-quinolin-1-ium diiodide Using HRMS and NMR". Phytochemistry, 2019, 486, (5), 2957-2969.
  4. Garcia M, Rodriguez P. "Forced Degradation Studies to Evaluate 4-[2-[4-[2-methoxy-5-[2-(1-methylquinolin-1-ium-4-yl)ethyl]phenoxy]phenyl]ethyl]-1-methyl-quinolin-1-ium diiodide Profile in Drug Substances According to ICH Guidelines". Rapid Commun. Mass Spectrom., 2019, 219, 9659-9683.

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