1-[2-[4-[5-[2-(4-hydroxy-1-isoquinolyl)ethyl]-2-methoxy-phenoxy]phenyl]ethyl]isoquinolin-4-ol CAS 365542-48-9

1-[2-[4-[5-[2-(4-hydroxy-1-isoquinolyl)ethyl]-2-methoxy-phenoxy]phenyl]ethyl]isoquinolin-4-ol

纯度 97%+现货药物标准品
CAS 号365542-48-9
分子式C35H30N2O4
分子量542.62 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

1-[2-[4-[5-[2-(4-hydroxy-1-isoquinolyl)ethyl]-2-methoxy-phenoxy]phenyl]ethyl]isoquinolin-4-ol 1-[2-[4-[5-[2-(4-hydroxy-1-isoquinolyl)ethyl]-2-methoxy-phenoxy]phenyl]ethyl]isoquinolin-4-ol CAS 365542-48-9 结构式 Chemical Structure

产品介绍 Description

CAS 365542-48-9 对应的1-[2-[4-[5-[2-(4-hydroxy-1-isoquinolyl)ethyl]-2-methoxy-phenoxy]phenyl]ethyl]isoquinolin-4-ol（1-[2-[4-[5-[2-(4-hydroxy-1-isoquinolyl)ethyl]-2-methoxy-phenoxy]phenyl]ethyl]isoquinolin-4-ol）为 CATO 佳途药物标准品产品线成员。分子式 C35H30N2O4，分子量 542.62。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。

与同类药物标准品相比，1-2-4-5-2-(4-hydroxy-1-isoquinolyl)ethyl-2-methoxy-phenoxyphenylethylisoquinolin-4-ol的分子量为542.62 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 1-2-4-5-2-(4-hydroxy-1-isoquinolyl)ethyl-2-methoxy-phenoxyphenylethylisoquinolin-4-ol（1-2-4-5-2-(4-hydroxy-1-isoquinolyl)ethyl-2-methoxy-phenoxyphenylethylisoquinolin-4-ol），CAS注册编号 365542-48-9，化学分子式为 C35H30N2O4，分子量 542.62 g/mol。 受分子结构中含氮杂环结构，酰胺类，含羟基，含醚键的影响，1-2-4-5-2-(4-hydroxy-1-isoquinolyl)ethyl-2-methoxy-phenoxyphenyleth

应用场景：在化学分析实验室中，1- 2- 4- 5- 2-(4-hydroxy-1-isoquinolyl)ethyl -2-methoxy-phenoxy phenyl ethyl isoquinolin-4-ol（CAS 365542-48-9）凭借其97%+的纯度做为基础物质，为定量分析提供基准参照。 推荐以1- 2- 4- 5- 2-(4-hydroxy-1-isoquinolyl)ethyl -2-methoxy-phenoxy phenyl ethyl isoquinolin-4-ol配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇/乙腈（1:1）为溶剂配制储备溶液，根

理化性质 Physical & Chemical Properties

中文名称1-[2-[4-[5-[2-(4-hydroxy-1-isoquinolyl)ethyl]-2-methoxy-phenoxy]phenyl]ethyl]isoquinolin-4-ol
分子式C35H30N2O4
分子量542.62 g/mol
外观形态淡黄色至黄色结晶性粉末
纯度97%+
储存条件阴凉处（≤25°C）保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）22.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）2025年
含氮原子数2

相关专利 Related Patents

  1. 发明人朱建伟，赵玉洁，郭海燕. "一种1-[2-[4-[5-[2-(4-hydroxy-1-isoquinolyl)ethyl]-2-methoxy-phenoxy]phenyl]ethyl]isoquinolin-4-ol的合成方法" [P]. 中国发明专利, 专利号 CN 116376631 A, 授权公告日 2024-10-02.
  2. 发明人林芳，周伟，何建平. "Method for the Synthesis of 1-[2-[4-[5-[2-(4-hydroxy-1-isoquinolyl)ethyl]-2-methoxy-phenoxy]phenyl]ethyl]isoquinolin-4-ol" [P]. 中国发明专利, 专利号 CN 111418525 A, 授权公告日 2018-10-25.

参考文献 Literature

  1. Zhou X P, Huang L, Wu G. "Development and Validation of an LC-MS/MS Method for the Determination of 1-[2-[4-[5-[2-(4-hydroxy-1-isoquinolyl)ethyl]-2-methoxy-phenoxy]phenyl]ethyl]isoquinolin-4-ol in Pharmaceutical Formulations". Anal. Chim. Acta, 2019, 189, 4783-4810.
  2. Wang L, Li J, Zhang H. "A Stability-Indicating HPLC Method for the Separation and Quantification of 1-[2-[4-[5-[2-(4-hydroxy-1-isoquinolyl)ethyl]-2-methoxy-phenoxy]phenyl]ethyl]isoquinolin-4-ol as an Impurity". Chromatographia, 2017, 267, 5298-5328.
  3. Kowalski T, Nowak Z. "Identification and Structural Characterization of a Novel Degradation Product of 1-[2-[4-[5-[2-(4-hydroxy-1-isoquinolyl)ethyl]-2-methoxy-phenoxy]phenyl]ethyl]isoquinolin-4-ol Using HRMS and NMR". Chemosphere, 2017, 1620, (3), 2906-2925.
  4. Jensen P, Larsen A M, Olsen K. "Forced Degradation Studies to Evaluate 1-[2-[4-[5-[2-(4-hydroxy-1-isoquinolyl)ethyl]-2-methoxy-phenoxy]phenyl]ethyl]isoquinolin-4-ol Profile in Drug Substances According to ICH Guidelines". Environ. Sci. Technol., 2025, 1250, (9), 6715-6740.

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