(3S,7R,10R,13S)-7-HYDROXY-10,13-DIMETHYL-17-OXO-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-YL ACETATE CAS 37976-96-8

(3S,7R,10R,13S)-7-HYDROXY-10,13-DIMETHYL-17-OXO-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-YL ACETATE

纯度 97%+现货药物标准品
CAS 号37976-96-8
分子式C21H30O4
分子量346.46 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

(3S,7R,10R,13S)-7-HYDROXY-10,13-DIMETHYL-17-OXO-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-YL ACETATE (3S,7R,10R,13S)-7-HYDROXY-10,13-DIMETHYL-17-OXO-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-YL ACETATE CAS 37976-96-8 结构式 Chemical Structure

产品介绍 Description

(3S,7R,10R,13S)-7-HYDROXY-10,13-DIMETHYL-17-OXO-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-YL ACETATE（(3S,7R,10R,13S)-7-HYDROXY-10,13-DIMETHYL-17-OXO-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-YL ACETATE）是药物分析与质量控制领域常用的药物标准品，CAS 号 37976-96-8。分子式 C21H30O4，分子量 346.46。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

(3S,7R,10R,13S)-7-HYDROXY-10,13-DIMETHYL-17-OXO-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTAAPHENANTHREN-3-YL ACETATE（分子式 C21H30O4）的化学结构中包含黄酮骨架，含羟基，含醚键。在反相色谱体系中，其保留行为主要受其较高的疏水性（logP）影响，这为HPLC-UV/DAD或LC-MS方法的建立提供了重要依据。较高的碳氢原子比赋予该化合物良好的脂溶性，可使用正己烷或乙酸乙酯等非极性溶剂进行液-液萃取前处理。 化学式为 C21H30O4 的(3S,7R,10R,13S)-7-HYDROXY-10,13-DIMETHYL-17-OXO-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTAAPHENANTHREN-3-YL ACETATE（(3S,7R,10R,13S)-7-HYDROXY-10,13-DIMETHYL-17-OXO-2,3,4,7

应用场景：在化学分析实验室中，(3S,7R,10R,13S)-7-HYDROXY-10,13-DIMETHYL-17-OXO-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA A PHENANTHREN-3-YL ACETATE（CAS 37976-96-8）凭借其97%+的纯度做为基础物质，为定量分析提供基准参照。 推荐以(3S,7R,10R,13S)-7-HYDROXY-10,13-DIMETHYL-17-OXO-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H

理化性质 Physical & Chemical Properties

中文名称(3S,7R,10R,13S)-7-HYDROXY-10,13-DIMETHYL-17-OXO-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-YL ACETATE
分子式C21H30O4
分子量346.46 g/mol
外观形态类白色至淡黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）7.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1967年

相关专利 Related Patents

  1. Lefèvre J P, Nielsen H, Kowalski A. "一种(3S,7R,10R,13S)-7-HYDROXY-10,13-DIMETHYL-17-OXO-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-YL ACETATE的合成方法" [P]. European Patent, EP 3294439 A1, 2017-09-19.
  2. 发明人林芳，钱学锋，陈志强. "Method for the Synthesis of (3S,7R,10R,13S)-7-HYDROXY-10,13-DIMETHYL-17-OXO-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-YL ACETATE" [P]. 中国发明专利, 专利号 CN 117587864 A, 授权公告日 2021-04-01.
  3. Björnsson E, Jørgensen K, Sørensen M. "A Process for Preparing High-Purity (3S,7R,10R,13S)-7-HYDROXY-10,13-DIMETHYL-17-OXO-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-YL ACETATE" [P]. European Patent, EP 3615336 A1, 2017-04-22.

参考文献 Literature

  1. Zhou X P, Huang L, Wu G. "Development and Validation of an LC-MS/MS Method for the Determination of (3S,7R,10R,13S)-7-HYDROXY-10,13-DIMETHYL-17-OXO-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-YL ACETATE in Pharmaceutical Formulations". Chromatographia, 2025, 2123, 9320-9349.
  2. Yamamoto K, Tanaka H, Suzuki T. "A Stability-Indicating HPLC Method for the Separation and Quantification of (3S,7R,10R,13S)-7-HYDROXY-10,13-DIMETHYL-17-OXO-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-YL ACETATE as an Impurity". Phytochemistry, 2024, 2184, 1834-1845.
  3. Jensen P, Larsen A M, Olsen K. "Identification and Structural Characterization of a Novel Degradation Product of (3S,7R,10R,13S)-7-HYDROXY-10,13-DIMETHYL-17-OXO-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-YL ACETATE Using HRMS and NMR". Chemosphere, 2024, 516, (9), 8371-8397.
  4. Zhou X P, Huang L, Wu G. "Forced Degradation Studies to Evaluate (3S,7R,10R,13S)-7-HYDROXY-10,13-DIMETHYL-17-OXO-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-YL ACETATE Profile in Drug Substances According to ICH Guidelines". Molecules, 2017, 1823, (9), 1965-1980.

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