6-三氟甲基-3-吡啶甲醇 CAS 386704-04-7

6-(Trifluoromethyl)pyridine-3-methanol 6-trifluoromethyl-3-pyridylmethanol [6-(trifluoromethyl)-3-pyridyl]methanol (6-trifluoromethyl-pyridin3-yl)-methanol 5-(hydroxymethyl)-2-(trifluoromethyl)pyridine 3-hydroxymethyl-6-trifluoromethylpyridine [6-(trifluoromethyl)pyridin-3-yl]methanol (6-(trifluoromethyl)pyridin-3-yl)methanol 2-(trifluoromethyl)pyridine-5-methanol (6-trifluoromethyl-pyridin-3-yl)-methanol [6-(trifluoromethyl)-3-pyridinyl]methanol 6-trifluoromethyl-3-pyridinemethanol 386704-04-7

纯度 97%+现货药物标准品
CAS 号386704-04-7
分子式C7H12F3NO
分子量183.17 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

6-三氟甲基-3-吡啶甲醇 6-(Trifluoromethyl)pyridine-3-methanol 6-trifluoromethyl-3-pyridylmethanol [6-(trifluoromethyl)-3-pyridyl]methanol (6-trifluoromethyl-pyridin3-yl)-methanol 5-(hydroxymethyl)-2-(trifluoromethyl)pyridine 3-hydroxymethyl-6-trifluoromethylpyridine [6-(trifluoromethyl)pyridin-3-yl]methanol (6-(trifluoromethyl)pyridin-3-yl)methanol 2-(trifluoromethyl)pyridine-5-methanol (6-trifluoromethyl-pyridin-3-yl)-methanol [6-(trifluoromethyl)-3-pyridinyl]methanol 6-trifluoromethyl-3-pyridinemethanol 386704-04-7 CAS 386704-04-7 结构式 Chemical Structure

产品介绍 Description

6-三氟甲基-3-吡啶甲醇（英文名 6-(Trifluoromethyl)pyridine-3-methanol 6-trifluoromethyl-3-pyridylmethanol [6-(trifluoromethyl)-3-pyridyl]methanol (6-trifluoromethyl-pyridin3-yl)-methanol 5-(hydroxymethyl)-2-(trifluoromethyl)pyridine 3-hydroxymethyl-6-trifluoromethylpyridine [6-(trifluoromethyl)pyridin-3-yl]methanol (6-(trifluoromethyl)pyridin-3-yl)methanol 2-(trifluoromethyl)pyridine-5-methanol (6-trifluoromethyl-pyridin-3-yl)-methanol [6-(trifluoromethyl)-3-pyridinyl]methanol 6-trifluoromethyl-3-pyridinemethanol 386704-04-7，CAS 386704-04-7）属于药物标准品。分子式 C7H12F3NO，分子量 183.17。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

6-三氟甲基-3-吡啶甲醇（分子式 C7H12F3NO）的化学结构中包含酰胺类，含羟基，含醚键，含氟取代。在反相色谱体系中，其保留行为主要受含氮官能团的质子化状态影响，这为HPLC-UV/DAD或LC-MS方法的建立提供了重要依据。因分子内存在卤素取代基（F/Cl/Br/I），该化合物在质谱分析中呈现特征性的同位素分布模式，可作为定性确认的重要依据。 6-三氟甲基-3-吡啶甲醇（6-(Trifluoromethyl)pyridine-3-methanol 6-trifluoromethyl-3-pyridylmethanol 6-(trifluoromethyl)-3-pyridylmethanol (6-trifluoromethyl-pyridin3-yl)-methanol 5-(hydroxymethyl)-2-(trifluoromethyl)pyridine 3-hydroxymethyl-6-trifluoromethylpyridine 6-(trifluoromethyl)pyridin-3-ylmethanol (6-(trifluoromethyl)py

应用场景：针对化学分析用途，6-三氟甲基-3-吡啶甲醇（6-(Trifluoromethyl)pyridine-3-methanol 6-trifluoromethyl-3-pyridylmethanol 6-(trifluoromethyl)-3-pyridyl methanol (6-trifluoromethyl-pyridin3-yl)-methanol 5-(hydroxymethyl)-2-(trifluoromethyl)pyridine 3-hydroxymethyl-6-trifluoromethylpyridine 6-(trifluoromethyl)pyridin-3-yl

理化性质 Physical & Chemical Properties

中文名称6-三氟甲基-3-吡啶甲醇
分子式C7H12F3NO
分子量183.17 g/mol
外观形态白色至类白色结晶性粉末。（具有轻微卤代物特征气味，具有氨/胺类微弱气味，挥发性较低）
纯度97%+
储存条件2-8°C冷藏保存，避光，密闭保存防止挥发
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）1.0
CAS登记年份（估）2025年
卤素含量F取代
含氮原子数1

相关专利 Related Patents

  1. 发明人周伟，胡光，孙丽萍. "一种6-三氟甲基-3-吡啶甲醇的合成方法" [P]. 中国发明专利, 专利号 CN 116947568 B, 授权公告日 2023-01-10.
  2. 发明人朱建伟，韩伟，冯建国. "Method for the Synthesis of 6-(Trifluoromethyl)pyridine-3-methanol 6-trifluoromethyl-3-pyridylmethanol [6-(trifluoromethyl)-3-pyridyl]methanol (6-trifluoromethyl-pyridin3-yl)-methanol 5-(hydroxymethyl)-2-(trifluoromethyl)pyridine 3-hydroxymethyl-6-trifluoromethylpyridine [6-(trifluoromethyl)pyridin-3-yl]methanol (6-(trifluoromethyl)pyridin-3-yl)methanol 2-(trifluoromethyl)pyridine-5-methanol (6-trifluoromethyl-pyridin-3-yl)-methanol [6-(trifluoromethyl)-3-pyridinyl]methanol 6-trifluoromethyl-3-pyridinemethanol 386704-04-7" [P]. 中国发明专利, 专利号 CN 109879017 B, 授权公告日 2021-02-04.

参考文献 Literature

  1. Chen X Y, Liu M, Zhao W Q. "Development and Validation of an LC-MS/MS Method for the Determination of 6-三氟甲基-3-吡啶甲醇 in Pharmaceutical Formulations". Biomed. Chromatogr., 2023, 571, 4002-4018.
  2. O'Brien K, Kennedy M L. "A Stability-Indicating HPLC Method for the Separation and Quantification of 6-三氟甲基-3-吡啶甲醇 as an Impurity". J. Sep. Sci., 2025, 1245, 306-311.
  3. Xu M, Hu Y, Zhou D. "Identification and Structural Characterization of a Novel Degradation Product of 6-(Trifluoromethyl)pyridine-3-methanol 6-trifluoromethyl-3-pyridylmethanol [6-(trifluoromethyl)-3-pyridyl]methanol (6-trifluoromethyl-pyridin3-yl)-methanol 5-(hydroxymethyl)-2-(trifluoromethyl)pyridine 3-hydroxymethyl-6-trifluoromethylpyridine [6-(trifluoromethyl)pyridin-3-yl]methanol (6-(trifluoromethyl)pyridin-3-yl)methanol 2-(trifluoromethyl)pyridine-5-methanol (6-trifluoromethyl-pyridin-3-yl)-methanol [6-(trifluoromethyl)-3-pyridinyl]methanol 6-trifluoromethyl-3-pyridinemethanol 386704-04-7 Using HRMS and NMR". J. Chromatogr. A, 2014, 1601, (9), 9418-9434.

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