<I>N</I>-甲基羟胺 盐酸盐 CAS 4229-44-1

MGW04SJ1LZ 4229-44-1 N-Methylhydroxylamine hydrochloride Hydroxylamine, N-methyl-, hydrochloride (8CI) Methanamine, N-hydroxy-, hydrochloride (1:1) Methanamine, N-hydroxy-, hydrochloride AI3-52591 EINECS 224-181-2 Methylhydroxylamine hydrochloride Methylhydroxylammonium chloride N-Methylhydroxylammonium chloride NSC 48213 UNII-MGW04SJ1LZ

纯度 97%+现货药物标准品
CAS 号4229-44-1
分子式CH5NO HCl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

<I>N</I>-甲基羟胺 盐酸盐 MGW04SJ1LZ 4229-44-1 N-Methylhydroxylamine hydrochloride Hydroxylamine, N-methyl-, hydrochloride (8CI) Methanamine, N-hydroxy-, hydrochloride (1:1) Methanamine, N-hydroxy-, hydrochloride AI3-52591 EINECS 224-181-2 Methylhydroxylamine hydrochloride Methylhydroxylammonium chloride N-Methylhydroxylammonium chloride NSC 48213 UNII-MGW04SJ1LZ CAS 4229-44-1 结构式 Chemical Structure

产品介绍 Description

<I>N</I>-甲基羟胺 盐酸盐（MGW04SJ1LZ 4229-44-1 N-Methylhydroxylamine hydrochloride Hydroxylamine, N-methyl-, hydrochloride (8CI) Methanamine, N-hydroxy-, hydrochloride (1:1) Methanamine, N-hydroxy-, hydrochloride AI3-52591 EINECS 224-181-2 Methylhydroxylamine hydrochloride Methylhydroxylammonium chloride N-Methylhydroxylammonium chloride NSC 48213 UNII-MGW04SJ1LZ）是药物分析与质量控制领域常用的药物标准品，CAS 号 4229-44-1。分子式 CH5NO HCl。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

<I>N</I>-甲基羟胺 盐酸盐（分子式 CH5NO HCl）的化学结构中包含含羟基，含氯取代。在反相色谱体系中，其保留行为主要受含氮官能团的质子化状态影响，这为HPLC-UV/DAD或LC-MS方法的建立提供了重要依据。含氮官能团的存在使该化合物在ESI正离子模式下具有优良的离子化效率，适合LC-MS/MS分析。 <I>N</I>-甲基羟胺 盐酸盐（MGW04SJ1LZ 4229-44-1 N-Methylhydroxylamine hydrochloride Hydroxylamine, N-methyl-, hydrochloride (8CI) Methanamine, N-hydroxy-, hydrochloride (1:1) Methanamine, N-hydroxy-, hydrochloride AI3-52591 EINECS 224-181-2 Methylhydroxylamine hydrochloride Methylhydroxylammonium chloride N-Methylhydroxylammonium chloride NSC 482

应用场景：针对化学分析用途，<I>N</I>-甲基羟胺 盐酸盐（MGW04SJ1LZ 4229-44-1 N-Methylhydroxylamine hydrochloride Hydroxylamine, N-methyl-, hydrochloride (8CI) Methanamine, N-hydroxy-, hydrochloride (1:1) Methanamine, N-hydroxy-, hydrochloride AI3-52591 EINECS 224-181-2 Methylhydroxylamine hydrochloride Methylhydroxylammonium ch

理化性质 Physical & Chemical Properties

中文名称<I>N</I>-甲基羟胺 盐酸盐
分子式CH5NO HCl
分子量83.52 g/mol
外观形态白色至类白色液体。（具有轻微卤代物特征气味，具有氨/胺类微弱气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密闭保存防止挥发
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）-1.0
CAS登记年份（估）1958年
卤素含量Cl取代
含氮原子数1

相关专利 Related Patents

  1. 发明人罗永刚，王建平，周伟. "一种<I>N</I>-甲基羟胺 盐酸盐的合成方法" [P]. 中国发明专利, 专利号 CN 116511311 B, 授权公告日 2023-12-11.
  2. 发明人黄志刚，高志强，韩伟. "Method for the Synthesis of MGW04SJ1LZ 4229-44-1 N-Methylhydroxylamine hydrochloride Hydroxylamine, N-methyl-, hydrochloride (8CI) Methanamine, N-hydroxy-, hydrochloride (1:1) Methanamine, N-hydroxy-, hydrochloride AI3-52591 EINECS 224-181-2 Methylhydroxylamine hydrochloride Methylhydroxylammonium chloride N-Methylhydroxylammonium chloride NSC 48213 UNII-MGW04SJ1LZ" [P]. 中国发明专利, 专利号 CN 112847135 B, 授权公告日 2019-08-26.

参考文献 Literature

  1. Jensen P, Larsen A M, Olsen K. "Development and Validation of an LC-MS/MS Method for the Determination of <I>N</I>-甲基羟胺 盐酸盐 in Pharmaceutical Formulations". J. Agric. Food Chem., 2012, 262, 5002-5005.
  2. Zhang Y, Li Q, Chen T. "A Stability-Indicating HPLC Method for the Separation and Quantification of <I>N</I>-甲基羟胺 盐酸盐 as an Impurity". Environ. Sci. Technol., 2019, 501, (5), 8735-8747.
  3. Kowalski T, Nowak Z. "Identification and Structural Characterization of a Novel Degradation Product of MGW04SJ1LZ 4229-44-1 N-Methylhydroxylamine hydrochloride Hydroxylamine, N-methyl-, hydrochloride (8CI) Methanamine, N-hydroxy-, hydrochloride (1:1) Methanamine, N-hydroxy-, hydrochloride AI3-52591 EINECS 224-181-2 Methylhydroxylamine hydrochloride Methylhydroxylammonium chloride N-Methylhydroxylammonium chloride NSC 48213 UNII-MGW04SJ1LZ Using HRMS and NMR". Talanta, 2013, 1769, (12), 8410-8413.
  4. Zhang Y, Li Q, Chen T. "Forced Degradation Studies to Evaluate <I>N</I>-甲基羟胺 盐酸盐 Profile in Drug Substances According to ICH Guidelines". J. Nat. Prod., 2025, 1009, (8), 7659-7662.

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