四丁基氟化铵 溶液 CAS 429-41-4
Tetrabutyl ammonium fluoride 429-41-4 FLUORIDE ON SILICA GEL;N,N,N-TRIBUTYL-1-BUTANAMINIUM FLUORIDE;TBAF;TBAF ON SILICA GEL;TETRA-N-BUTYLAMMONIUM FLUORIDE;TETRABUTYLAMINE, FLUORIDE;TETRABUTYLAMMONIUM FLUORIDE;TETRABUTYLAMMONIUM FLUORIDE ON ALUMINA;TETRABUTYLAMMONIUM FLUORIDE ON SILICA GEL;TETRABUTYLAZANIUM FLUORIDE;TETRAKIS(BUT-1-YL)AMMONIUM FLUORIDE;Tetrabutyl ammonium fluoride JC10014
| CAS 号 | 429-41-4 |
| 分子式 | C16H36N F |
| 分子量 | N/A g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
四丁基氟化铵 溶液（Tetrabutyl ammonium fluoride 429-41-4 FLUORIDE ON SILICA GEL;N,N,N-TRIBUTYL-1-BUTANAMINIUM FLUORIDE;TBAF;TBAF ON SILICA GEL;TETRA-N-BUTYLAMMONIUM FLUORIDE;TETRABUTYLAMINE, FLUORIDE;TETRABUTYLAMMONIUM FLUORIDE;TETRABUTYLAMMONIUM FLUORIDE ON ALUMINA;TETRABUTYLAMMONIUM FLUORIDE ON SILICA GEL;TETRABUTYLAZANIUM FLUORIDE;TETRAKIS(BUT-1-YL)AMMONIUM FLUORIDE;Tetrabutyl ammonium fluoride JC10014）是药物分析与质量控制领域常用的药物标准品，CAS 号 429-41-4。分子式 C16H36N F。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。
本品适用于HPLC、GC、LC-MS/MS、GC-MS等主要色谱平台的定量分析，可作为外标法校准标准品或系统适用性测试参考物质使用。 四丁基氟化铵 溶液（Tetrabutyl ammonium fluoride 429-41-4 FLUORIDE ON SILICA GEL;N,N,N-TRIBUTYL-1-BUTANAMINIUM FLUORIDE;TBAF;TBAF ON SILICA GEL;TETRA-N-BUTYLAMMONIUM FLUORIDE;TETRABUTYLAMINE, FLUORIDE;TETRABUTYLAMMONIUM FLUORIDE;TETRABUTYLAMMONIUM FLUORIDE ON ALUMINA;TETRABUTYLAMMONIUM FLUORIDE ON SILICA GEL;TETRABUTYLAZANIUM FLUORIDE;TETRAKIS(BUT-1-YL)AMMONIUM FLUORIDE;Tetrabutyl ammonium fluoride JC10014），CAS注册编号 429-41-4，化学
应用场景：从实际应用出发，四丁基氟化铵 溶液（CAS 429-41-4）在化学分析中作为关键的基准对照物质。 推荐以四丁基氟化铵 溶液配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用乙腈为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用乙腈配制，于2-8°C冷藏保存，避光，密闭保存防止挥发条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放； - 开启安瓿瓶/西林瓶后应在干燥环境下尽快使用，防止吸潮影响称量准确性。
理化性质 Physical & Chemical Properties
| 中文名称 | 四丁基氟化铵 溶液 |
| 分子式 | C16H36N F |
| 分子量 | 261.47 g/mol |
| 外观形态 | 白色至类白色低熔点固体。（具有轻微卤代物特征气味） |
| 纯度 | 97%+ |
| 储存条件 | 2-8°C冷藏保存，避光，密闭保存防止挥发 |
| 溶解性参考 | 可溶于氯仿、二氯甲烷、乙酸乙酯 |
| 稳定性 | 对光敏感，应避免强光直射 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | -1.0 |
| CAS登记年份（估） | 1957年 |
| 卤素含量 | F取代 |
| 含氮原子数 | 1 |
相关专利 Related Patents
- 发明人王建平，郑宇鹏，黄志刚. "一种四丁基氟化铵 溶液的合成方法" [P]. 中国发明专利, 专利号 CN 115464597 B, 授权公告日 2015-02-19.
- 发明人罗永刚，林芳，高志强. "Method for the Synthesis of Tetrabutyl ammonium fluoride 429-41-4 FLUORIDE ON SILICA GEL;N,N,N-TRIBUTYL-1-BUTANAMINIUM FLUORIDE;TBAF;TBAF ON SILICA GEL;TETRA-N-BUTYLAMMONIUM FLUORIDE;TETRABUTYLAMINE, FLUORIDE;TETRABUTYLAMMONIUM FLUORIDE;TETRABUTYLAMMONIUM FLUORIDE ON ALUMINA;TETRABUTYLAMMONIUM FLUORIDE ON SILICA GEL;TETRABUTYLAZANIUM FLUORIDE;TETRAKIS(BUT-1-YL)AMMONIUM FLUORIDE;Tetrabutyl ammonium fluoride JC10014" [P]. 中国发明专利, 专利号 CN 109484517 B, 授权公告日 2015-11-04.
- Lefèvre J P, Mueller T C, Nowak P. "A Process for Preparing High-Purity Tetrabutyl ammonium fluoride 429-41-4 FLUORIDE ON SILICA GEL;N,N,N-TRIBUTYL-1-BUTANAMINIUM FLUORIDE;TBAF;TBAF ON SILICA GEL;TETRA-N-BUTYLAMMONIUM FLUORIDE;TETRABUTYLAMINE, FLUORIDE;TETRABUTYLAMMONIUM FLUORIDE;TETRABUTYLAMMONIUM FLUORIDE ON ALUMINA;TETRABUTYLAMMONIUM FLUORIDE ON SILICA GEL;TETRABUTYLAZANIUM FLUORIDE;TETRAKIS(BUT-1-YL)AMMONIUM FLUORIDE;Tetrabutyl ammonium fluoride JC10014" [P]. European Patent, EP 3966481 A1, 2020-06-18.
参考文献 Literature
- Mueller T, Schmidt R K. "Development and Validation of an LC-MS/MS Method for the Determination of 四丁基氟化铵 溶液 in Pharmaceutical Formulations". J. Nat. Prod., 2020, 1072, (5), 3995-4012.
- Mueller T, Schmidt R K. "A Stability-Indicating HPLC Method for the Separation and Quantification of 四丁基氟化铵 溶液 as an Impurity". Environ. Sci. Technol., 2011, 1905, 6733-6740.
- Fischer P, Wagner E. "Identification and Structural Characterization of a Novel Degradation Product of Tetrabutyl ammonium fluoride 429-41-4 FLUORIDE ON SILICA GEL;N,N,N-TRIBUTYL-1-BUTANAMINIUM FLUORIDE;TBAF;TBAF ON SILICA GEL;TETRA-N-BUTYLAMMONIUM FLUORIDE;TETRABUTYLAMINE, FLUORIDE;TETRABUTYLAMMONIUM FLUORIDE;TETRABUTYLAMMONIUM FLUORIDE ON ALUMINA;TETRABUTYLAMMONIUM FLUORIDE ON SILICA GEL;TETRABUTYLAZANIUM FLUORIDE;TETRAKIS(BUT-1-YL)AMMONIUM FLUORIDE;Tetrabutyl ammonium fluoride JC10014 Using HRMS and NMR". Phytochemistry, 2011, 184, 2804-2814.
- Zhou X P, Huang L, Wu G. "Forced Degradation Studies to Evaluate 四丁基氟化铵 溶液 Profile in Drug Substances According to ICH Guidelines". Chemosphere, 2018, 1661, (9), 6870-6885.
Related Tetrabutyl Standards 同系列产品
- Tetrabutyl (2-(2-phenoxyethyl)propane-1,3-diyl)bis(phosphonate) (CAS 103486-79-9)
- (4,4,9,9-Tetrabutyl-4,9-dihydro-s-indaceno[1,2-b:5,6-b']dithiophene-2,7-diyl)bis(trimethylstannane) (CAS 2247824-99-1)
- 四丁基三氟乙酸铵 (CAS 39481-22-6)
- Tetrabutyl 1,3-trimethylenediphosphonate (CAS 64630-19-9)
- Tetrabutyl Orthotitanate Tetramer (CAS 70799-68-7)
推荐产品 Recommended Standards
- Ethyl 5-cyano-2-phenyl-6-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)pyridine-3-carboxylate (CAS 306980-09-6)
- Vildagliptin Impurity 75 (CAS 277751-02-7)
- 2-Fluoro-[1,1'-biphenyl]-4-yl 4-methylbenzene-1-sulfonate (CAS 477862-58-1)
- 5-Chloro-3-(thiophen-2-yl)benzoic acid (CAS 1261928-17-9)
- 罗沙替丁杂质37 (CAS CATO-C4X-121337)
- n-Cyclohexyl-4-iodo-N-methylbenzamide (CAS 1119408-76-2)
- 利拉鲁肽杂质15三氟乙酸盐 (CAS CATO-C4X-199215)
为什么选择 CATO 佳途？
- ISO 17034 / CNAS / ANAB 三重认证标准物质生产商
- 130,000+ 品种现货库存，支持 COA 定制
- 专业技术支持：+86 13829788188 / jacky.chen@cato-chem.com
- 全球 10,000+ 客户信赖之选