18:1 DGPP CAS 474943-14-1

474943-14-1 VSK5Q66IWS Dioleoylglycerol pyrophosphate ammonium salt UNII-VSK5Q66IWS 1,2-Dioleoyl-sn-glycero-pyrophosphate (ammonium salt) 9-Octadecenoic acid (9Z)-, (1R)-1-(3,5,5-trihydroxy-3,5-dioxido-2,4-dioxa-3,5-diphosphapent-1-yl)-1,2-ethanediyl ester, diammonium salt

纯度 97%+现货药物标准品
CAS 号474943-14-1
分子式C39H72O11P2 2*H4N
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

18:1 DGPP 474943-14-1 VSK5Q66IWS Dioleoylglycerol pyrophosphate ammonium salt UNII-VSK5Q66IWS 1,2-Dioleoyl-sn-glycero-pyrophosphate (ammonium salt) 9-Octadecenoic acid (9Z)-, (1R)-1-(3,5,5-trihydroxy-3,5-dioxido-2,4-dioxa-3,5-diphosphapent-1-yl)-1,2-ethanediyl ester, diammonium salt CAS 474943-14-1 结构式 Chemical Structure

产品介绍 Description

18:1 DGPP（英文名 474943-14-1 VSK5Q66IWS Dioleoylglycerol pyrophosphate ammonium salt UNII-VSK5Q66IWS 1,2-Dioleoyl-sn-glycero-pyrophosphate (ammonium salt) 9-Octadecenoic acid (9Z)-, (1R)-1-(3,5,5-trihydroxy-3,5-dioxido-2,4-dioxa-3,5-diphosphapent-1-yl)-1,2-ethanediyl ester, diammonium salt，CAS 474943-14-1）属于药物标准品。分子式 C39H72O11P2 2*H4N。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

推荐用于分析方法开发与验证，产品提供完整COA证书，确保ISO 17034标准的量值溯源要求。适用于GLP实验室的日常分析。 CAS编号 474943-14-1 对应的化合物18:1 DGPP（英文标识 474943-14-1 VSK5Q66IWS Dioleoylglycerol pyrophosphate ammonium salt UNII-VSK5Q66IWS 1,2-Dioleoyl-sn-glycero-pyrophosphate (ammonium salt) 9-Octadecenoic acid (9Z)-, (1R)-1-(3,5,5-trihydroxy-3,5-dioxido-2,4-dioxa-3,5-diphosphapent-1-yl)-1,2-ethanediyl ester, diammonium salt），化学式 C39H72O11P2 2H4N，相对分子质量 796.98。 18:1 DGPP（C39H72O11P2 2H4N）含有酰胺类，含磷酸酯基，羧酸类，含羟基，含醚键。羧基赋予其一定的酸性特征，这些物理化学性质直接决

应用场景：18:1 DGPP（474943-14-1 VSK5Q66IWS Dioleoylglycerol pyrophosphate ammonium salt UNII-VSK5Q66IWS 1,2-Dioleoyl-sn-glycero-pyrophosphate (ammonium salt) 9-Octadecenoic acid (9Z)-, (1R)-1-(3,5,5-trihydroxy-3,5-dioxido-2,4-dioxa-3,5-diphosphapent-1-yl)-1,2-ethanediyl ester, diammonium salt，CAS 474943-14-1）

理化性质 Physical & Chemical Properties

中文名称18:1 DGPP
分子式C39H72O11P2 2*H4N
分子量796.98 g/mol
外观形态白色至类白色无定形粉末
纯度97%+
储存条件室温保存，避光，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）2.5
CAS登记年份（估）2025年
含氮原子数1

相关专利 Related Patents

  1. 发明人王建平，朱建伟，赵玉洁. "一种18:1 DGPP的合成方法" [P]. 中国发明专利, 专利号 CN 115430213 B, 授权公告日 2023-07-05.
  2. Lee S K, Thompson G K, Schröder R. "Method for the Synthesis of 474943-14-1 VSK5Q66IWS Dioleoylglycerol pyrophosphate ammonium salt UNII-VSK5Q66IWS 1,2-Dioleoyl-sn-glycero-pyrophosphate (ammonium salt) 9-Octadecenoic acid (9Z)-, (1R)-1-(3,5,5-trihydroxy-3,5-dioxido-2,4-dioxa-3,5-diphosphapent-1-yl)-1,2-ethanediyl ester, diammonium salt" [P]. US Patent, US 9333124 B2, 2025-11-05.

参考文献 Literature

  1. Wang L, Li J, Zhang H. "Development and Validation of an LC-MS/MS Method for the Determination of 18:1 DGPP in Pharmaceutical Formulations". Chemosphere, 2013, 1355, (5), 7890-7912.
  2. Kowalski T, Nowak Z. "A Stability-Indicating HPLC Method for the Separation and Quantification of 18:1 DGPP as an Impurity". Anal. Methods, 2020, 842, 7863-7875.
  3. Yang F, Sun W, Liu J. "Identification and Structural Characterization of a Novel Degradation Product of 474943-14-1 VSK5Q66IWS Dioleoylglycerol pyrophosphate ammonium salt UNII-VSK5Q66IWS 1,2-Dioleoyl-sn-glycero-pyrophosphate (ammonium salt) 9-Octadecenoic acid (9Z)-, (1R)-1-(3,5,5-trihydroxy-3,5-dioxido-2,4-dioxa-3,5-diphosphapent-1-yl)-1,2-ethanediyl ester, diammonium salt Using HRMS and NMR". Anal. Chim. Acta, 2019, 1261, 8152-8171.
  4. Smith J A, Johnson M B. "Forced Degradation Studies to Evaluate 18:1 DGPP Profile in Drug Substances According to ICH Guidelines". Sci. Total Environ., 2024, 253, 6599-6620.

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