CAS 478148-58-2

Z7950E6X01 478148-58-2 PHA-543613 dihydrochloride UNII-Z7950E6X01 Furo(2,3-C)pyridine-5-carboxamide, N-(3R)-1-azabicyclo(2.2.2)oct-3-yl-, dihydrochloride Furo(2,3-C)pyridine-5-carboxamide, N-(3R)-1-azabicyclo(2.2.2)oct-3-yl-, hydrochloride (1:2) PHA-543613 dihydrochloride salt PHA-543613E

纯度 97%+现货药物标准品
CAS 号478148-58-2
分子式C15H17N3O2 2*HCl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

Z7950E6X01 478148-58-2 PHA-543613 dihydrochloride UNII-Z7950E6X01 Furo(2,3-C)pyridine-5-carboxamide, N-(3R)-1-azabicyclo(2.2.2)oct-3-yl-, dihydrochloride Furo(2,3-C)pyridine-5-carboxamide, N-(3R)-1-azabicyclo(2.2.2)oct-3-yl-, hydrochloride (1:2) PHA-543613 dihydrochloride salt PHA-543613E CAS 478148-58-2 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的（Z7950E6X01 478148-58-2 PHA-543613 dihydrochloride UNII-Z7950E6X01 Furo(2,3-C)pyridine-5-carboxamide, N-(3R)-1-azabicyclo(2.2.2)oct-3-yl-, dihydrochloride Furo(2,3-C)pyridine-5-carboxamide, N-(3R)-1-azabicyclo(2.2.2)oct-3-yl-, hydrochloride (1:2) PHA-543613 dihydrochloride salt PHA-543613E）为药物标准品，CAS 登记号 478148-58-2，分子式 C15H17N3O2 2*HCl。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括在内的目标物的控制。 （Z7950E6X01 478148-58-2 PHA-543613 dihydrochloride UNII-Z7950E6X01 Furo(2,3-C)pyridine-5-carboxamide, N-(3R)-1-azabicyclo(2.2.2)oct-3-yl-, dihydrochloride Furo(2,3-C)pyridine-5-carboxamide, N-(3R)-1-azabicyclo(2.2.2)oct-3-yl-, hydrochloride (1:2) PHA-543613 dihydrochloride salt PHA-543613E），CAS注册编号 478148-58-2，化学分子式为 C15H17N3O2 2HCl，分子量 307.78 g/mol。 受分子结构中含氮杂环结构，酰胺类，含羟基，含醚键，含氯取代的影响，表现为淡黄色至黄色结晶性粉末。（具有轻微卤代物特征气味）。其固体形态的物理化学属性——包括307.78 g/mol的分子量——对于选择合适的

应用场景：（Z7950E6X01 478148-58-2 PHA-543613 dihydrochloride UNII-Z7950E6X01 Furo(2,3-C)pyridine-5-carboxamide, N-(3R)-1-azabicyclo(2.2.2)oct-3-yl-, dihydrochloride Furo(2,3-C)pyridine-5-carboxamide, N-(3R)-1-azabicyclo(2.2.2)oct-3-yl-, hydrochloride (1:2) PHA-543613 dihydrochloride salt PHA-543613E，CAS 47814

理化性质 Physical & Chemical Properties

中文名称
分子式C15H17N3O2 2*HCl
分子量307.78 g/mol
外观形态淡黄色至黄色结晶性粉末。（具有轻微卤代物特征气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封；含酯键，遇强碱易水解
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）8.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）2025年
卤素含量Cl取代
含氮原子数3

相关专利 Related Patents

  1. Patel M V, Fischer A B, Thompson G K. "一种的合成方法" [P]. US Patent, US 10235913 B2, 2025-07-07.
  2. 发明人郭海燕，赵玉洁，林芳. "Method for the Synthesis of Z7950E6X01 478148-58-2 PHA-543613 dihydrochloride UNII-Z7950E6X01 Furo(2,3-C)pyridine-5-carboxamide, N-(3R)-1-azabicyclo(2.2.2)oct-3-yl-, dihydrochloride Furo(2,3-C)pyridine-5-carboxamide, N-(3R)-1-azabicyclo(2.2.2)oct-3-yl-, hydrochloride (1:2) PHA-543613 dihydrochloride salt PHA-543613E" [P]. 中国发明专利, 专利号 CN 110667849 A, 授权公告日 2022-03-26.

参考文献 Literature

  1. Wang L, Li J, Zhang H. "Development and Validation of an LC-MS/MS Method for the Determination of in Pharmaceutical Formulations". Chromatographia, 2017, 2169, 5185-5200.
  2. Kumar A, Sharma P, Patel R S. "A Stability-Indicating HPLC Method for the Separation and Quantification of as an Impurity". Anal. Chem., 2020, 2111, (5), 2645-2662.
  3. Kumar A, Sharma P, Patel R S. "Identification and Structural Characterization of a Novel Degradation Product of Z7950E6X01 478148-58-2 PHA-543613 dihydrochloride UNII-Z7950E6X01 Furo(2,3-C)pyridine-5-carboxamide, N-(3R)-1-azabicyclo(2.2.2)oct-3-yl-, dihydrochloride Furo(2,3-C)pyridine-5-carboxamide, N-(3R)-1-azabicyclo(2.2.2)oct-3-yl-, hydrochloride (1:2) PHA-543613 dihydrochloride salt PHA-543613E Using HRMS and NMR". J. Pharm. Biomed. Anal., 2015, 1832, 7682-7685.
  4. Fischer P, Wagner E. "Forced Degradation Studies to Evaluate Profile in Drug Substances According to ICH Guidelines". J. Agric. Food Chem., 2019, 786, (10), 1225-1231.

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