四异丙醇钛 CAS 546-68-9
76NX7K235Y 546-68-9 Tetraisopropyl titanate Titanium isopropoxide Titanium isopropylate Isopropyl alcohol, titanium(4+) salt Titanium tetraisopropanolate 2-Propanol, titanium(4+) salt (4:1) 2-Propanol, titanium(4+) salt EINECS 208-909-6 HSDB 848 Isopropyl alcohol, titanium salt Isopropyl alcohol titanium(4+) salt Isopropyl orthotitanate Isopropyl titanate(IV) Isopropyl titanate(IV) ((C3H7O)4Ti) NSC 60576 Tetraisopropoxide titanium Tetraisopropoxytitanium Tetraisopropyl orthotitanate Tetrakis(isopropoxy)titanium Ti Isopropylate Titanic acid isopropyl ester Titanic acid tetraisopropyl ester Titanic(IV) acid, tetraisopropyl ester Titanium(4+) isopropoxide Titanium isopropoxide (Ti(OCH7)4) Titanium isopropylate (VAN) Titanium tetraisopropoxide Titanium tetraisopropylate Titanium, tetrakis(1-methylethoxy)- Titanium tetra-n-propoxide Tyzor TPt Tetraisopropoxytitanium(IV) A 1 (titanate) Orgatix TA 10 TA 10 Tetraisopropanolatotitanium Tetraksi(isopropanolato)titanium Tilcom TIPT Titanium(IV) isopropoxide Titanium tetrakis(isopropoxide) UNII-76NX7K235Y EC 208-909-6
| CAS 号 | 546-68-9 |
| 分子式 | C12H28O4Ti |
| 分子量 | 284.22 g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
CATO 佳途供应的四异丙醇钛（76NX7K235Y 546-68-9 Tetraisopropyl titanate Titanium isopropoxide Titanium isopropylate Isopropyl alcohol, titanium(4+) salt Titanium tetraisopropanolate 2-Propanol, titanium(4+) salt (4:1) 2-Propanol, titanium(4+) salt EINECS 208-909-6 HSDB 848 Isopropyl alcohol, titanium salt Isopropyl alcohol titanium(4+) salt Isopropyl orthotitanate Isopropyl titanate(IV) Isopropyl titanate(IV) ((C3H7O)4Ti) NSC 60576 Tetraisopropoxide titanium Tetraisopropoxytitanium Tetraisopropyl orthotitanate Tetrakis(isopropoxy)titanium Ti Isopropylate Titanic acid isopropyl ester Titanic acid tetraisopropyl ester Titanic(IV) acid, tetraisopropyl ester Titanium(4+) isopropoxide Titanium isopropoxide (Ti(OCH7)4) Titanium isopropylate (VAN) Titanium tetraisopropoxide Titanium tetraisopropylate Titanium, tetrakis(1-methylethoxy)- Titanium tetra-n-propoxide Tyzor TPt Tetraisopropoxytitanium(IV) A 1 (titanate) Orgatix TA 10 TA 10 Tetraisopropanolatotitanium Tetraksi(isopropanolato)titanium Tilcom TIPT Titanium(IV) isopropoxide Titanium tetrakis(isopropoxide) UNII-76NX7K235Y EC 208-909-6）为药物标准品，CAS 登记号 546-68-9，分子式 C12H28O4Ti，分子量 284.22。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。
四异丙醇钛的产生途径与其化学式中羧酸类，含羟基，含醚键密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 化学式为 C12H28O4Ti 的四异丙醇钛（76NX7K235Y 546-68-9 Tetraisopropyl titanate Titanium isopropoxide Titanium isopropylate Isopropyl alcohol, titanium(4+) salt Titanium tetraisopropanolate 2-Propanol, titanium(4+) salt (4:1) 2-Propanol, titanium(4+) salt EINECS 208-909-6 HSDB 848 Isopropyl alcohol, titanium salt Isopropyl alcohol titanium(4+) salt Isopropyl orthotitanate Isopropyl titanate(IV) Isopropyl titanate(IV) ((C3H7O)4Ti) NSC 60576 Tetra
应用场景：从实际应用出发，四异丙醇钛（CAS 546-68-9）在化学分析中作为关键的基准对照物质。 推荐以四异丙醇钛配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用乙腈为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用乙腈配制，于阴凉处（≤25°C）保存，密封防潮条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放； - 开启安瓿瓶/西林瓶后应在干燥环境下尽快使用，防止吸潮影响称量准确性。
理化性质 Physical & Chemical Properties
| 中文名称 | 四异丙醇钛 |
| 分子式 | C12H28O4Ti |
| 分子量 | 284.22 g/mol |
| 外观形态 | 白色至类白色结晶性粉末 |
| 纯度 | 97%+ |
| 储存条件 | 阴凉处（≤25°C）保存，密封防潮 |
| 溶解性参考 | 可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO |
| 稳定性 | 具有吸湿性，开封后应立即密封 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | -1.0 |
| CAS登记年份（估） | 1957年 |
相关专利 Related Patents
- 发明人郭海燕，何建平，李文辉. "一种四异丙醇钛的合成方法" [P]. 中国发明专利, 专利号 CN 113213705 A, 授权公告日 2023-06-11.
- 发明人周伟，孙丽萍，陈志强. "Method for the Synthesis of 76NX7K235Y 546-68-9 Tetraisopropyl titanate Titanium isopropoxide Titanium isopropylate Isopropyl alcohol, titanium(4+) salt Titanium tetraisopropanolate 2-Propanol, titanium(4+) salt (4:1) 2-Propanol, titanium(4+) salt EINECS 208-909-6 HSDB 848 Isopropyl alcohol, titanium salt Isopropyl alcohol titanium(4+) salt Isopropyl orthotitanate Isopropyl titanate(IV) Isopropyl titanate(IV) ((C3H7O)4Ti) NSC 60576 Tetraisopropoxide titanium Tetraisopropoxytitanium Tetraisopropyl orthotitanate Tetrakis(isopropoxy)titanium Ti Isopropylate Titanic acid isopropyl ester Titanic acid tetraisopropyl ester Titanic(IV) acid, tetraisopropyl ester Titanium(4+) isopropoxide Titanium isopropoxide (Ti(OCH7)4) Titanium isopropylate (VAN) Titanium tetraisopropoxide Titanium tetraisopropylate Titanium, tetrakis(1-methylethoxy)- Titanium tetra-n-propoxide Tyzor TPt Tetraisopropoxytitanium(IV) A 1 (titanate) Orgatix TA 10 TA 10 Tetraisopropanolatotitanium Tetraksi(isopropanolato)titanium Tilcom TIPT Titanium(IV) isopropoxide Titanium tetrakis(isopropoxide) UNII-76NX7K235Y EC 208-909-6" [P]. 中国发明专利, 专利号 CN 116795011 B, 授权公告日 2016-11-12.
- 发明人陈志强，林芳，郑宇鹏. "A Process for Preparing High-Purity 76NX7K235Y 546-68-9 Tetraisopropyl titanate Titanium isopropoxide Titanium isopropylate Isopropyl alcohol, titanium(4+) salt Titanium tetraisopropanolate 2-Propanol, titanium(4+) salt (4:1) 2-Propanol, titanium(4+) salt EINECS 208-909-6 HSDB 848 Isopropyl alcohol, titanium salt Isopropyl alcohol titanium(4+) salt Isopropyl orthotitanate Isopropyl titanate(IV) Isopropyl titanate(IV) ((C3H7O)4Ti) NSC 60576 Tetraisopropoxide titanium Tetraisopropoxytitanium Tetraisopropyl orthotitanate Tetrakis(isopropoxy)titanium Ti Isopropylate Titanic acid isopropyl ester Titanic acid tetraisopropyl ester Titanic(IV) acid, tetraisopropyl ester Titanium(4+) isopropoxide Titanium isopropoxide (Ti(OCH7)4) Titanium isopropylate (VAN) Titanium tetraisopropoxide Titanium tetraisopropylate Titanium, tetrakis(1-methylethoxy)- Titanium tetra-n-propoxide Tyzor TPt Tetraisopropoxytitanium(IV) A 1 (titanate) Orgatix TA 10 TA 10 Tetraisopropanolatotitanium Tetraksi(isopropanolato)titanium Tilcom TIPT Titanium(IV) isopropoxide Titanium tetrakis(isopropoxide) UNII-76NX7K235Y EC 208-909-6" [P]. 中国发明专利, 专利号 CN 117779225 B, 授权公告日 2016-07-06.
参考文献 Literature
- Jensen P, Larsen A M, Olsen K. "Development and Validation of an LC-MS/MS Method for the Determination of 四异丙醇钛 in Pharmaceutical Formulations". Phytochemistry, 2014, 2449, (5), 1922-1945.
- Mueller T, Schmidt R K. "A Stability-Indicating HPLC Method for the Separation and Quantification of 四异丙醇钛 as an Impurity". Talanta, 2016, 188, (9), 2518-2533.
- Zhou X P, Huang L, Wu G. "Identification and Structural Characterization of a Novel Degradation Product of 76NX7K235Y 546-68-9 Tetraisopropyl titanate Titanium isopropoxide Titanium isopropylate Isopropyl alcohol, titanium(4+) salt Titanium tetraisopropanolate 2-Propanol, titanium(4+) salt (4:1) 2-Propanol, titanium(4+) salt EINECS 208-909-6 HSDB 848 Isopropyl alcohol, titanium salt Isopropyl alcohol titanium(4+) salt Isopropyl orthotitanate Isopropyl titanate(IV) Isopropyl titanate(IV) ((C3H7O)4Ti) NSC 60576 Tetraisopropoxide titanium Tetraisopropoxytitanium Tetraisopropyl orthotitanate Tetrakis(isopropoxy)titanium Ti Isopropylate Titanic acid isopropyl ester Titanic acid tetraisopropyl ester Titanic(IV) acid, tetraisopropyl ester Titanium(4+) isopropoxide Titanium isopropoxide (Ti(OCH7)4) Titanium isopropylate (VAN) Titanium tetraisopropoxide Titanium tetraisopropylate Titanium, tetrakis(1-methylethoxy)- Titanium tetra-n-propoxide Tyzor TPt Tetraisopropoxytitanium(IV) A 1 (titanate) Orgatix TA 10 TA 10 Tetraisopropanolatotitanium Tetraksi(isopropanolato)titanium Tilcom TIPT Titanium(IV) isopropoxide Titanium tetrakis(isopropoxide) UNII-76NX7K235Y EC 208-909-6 Using HRMS and NMR". Molecules, 2010, 80, 8338-8359.
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