四氢-2-（2-丙炔氧基）-2<I>H</I>-吡喃 CAS 6089-04-9

6089-04-9 2H-Pyran, tetrahydro-2-(2-propynyloxy)- (8CI)(9CI) Tetrahydro-2-(2-propynyloxy)-2H-pyran AI3-30238 EINECS 228-027-5 NSC 152714 Propargyl alcohol tetrahydropyranyl ether Propargyl 2-tetrahydropyranyl ether 2-Propargyloxane 2-(Propargyloxy)tetrahydropyran 2-Propynyl 2-pyranyl ether 2-(2-Propynyloxy)tetrahydropyran 1-(2'-Tetrahydropyranyloxy)-2-propyne 3-(2'-Tetrahydropyranyloxy)propyne

纯度 97%+现货药物标准品
CAS 号6089-04-9
分子式C8H12O2
分子量140.18 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

四氢-2-（2-丙炔氧基）-2<I>H</I>-吡喃 6089-04-9 2H-Pyran, tetrahydro-2-(2-propynyloxy)- (8CI)(9CI) Tetrahydro-2-(2-propynyloxy)-2H-pyran AI3-30238 EINECS 228-027-5 NSC 152714 Propargyl alcohol tetrahydropyranyl ether Propargyl 2-tetrahydropyranyl ether 2-Propargyloxane 2-(Propargyloxy)tetrahydropyran 2-Propynyl 2-pyranyl ether 2-(2-Propynyloxy)tetrahydropyran 1-(2'-Tetrahydropyranyloxy)-2-propyne 3-(2'-Tetrahydropyranyloxy)propyne CAS 6089-04-9 结构式 Chemical Structure

产品介绍 Description

四氢-2-（2-丙炔氧基）-2<I>H</I>-吡喃（英文名 6089-04-9 2H-Pyran, tetrahydro-2-(2-propynyloxy)- (8CI)(9CI) Tetrahydro-2-(2-propynyloxy)-2H-pyran AI3-30238 EINECS 228-027-5 NSC 152714 Propargyl alcohol tetrahydropyranyl ether Propargyl 2-tetrahydropyranyl ether 2-Propargyloxane 2-(Propargyloxy)tetrahydropyran 2-Propynyl 2-pyranyl ether 2-(2-Propynyloxy)tetrahydropyran 1-(2'-Tetrahydropyranyloxy)-2-propyne 3-(2'-Tetrahydropyranyloxy)propyne，CAS 6089-04-9）属于药物标准品。分子式 C8H12O2，分子量 140.18。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

与同类药物标准品相比，四氢-2-（2-丙炔氧基）-2<I>H</I>-吡喃的分子量为140.18 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 化学式为 C8H12O2 的四氢-2-（2-丙炔氧基）-2<I>H</I>-吡喃（6089-04-9 2H-Pyran, tetrahydro-2-(2-propynyloxy)- (8CI)(9CI) Tetrahydro-2-(2-propynyloxy)-2H-pyran AI3-30238 EINECS 228-027-5 NSC 152714 Propargyl alcohol tetrahydropyranyl ether Propargyl 2-tetrahydropyranyl ether 2-Propargyloxane 2-(Propargyloxy)tetrahydropyran 2-Propynyl 2-pyranyl ether 2-(2-Propynyloxy)tetrahydropyran 1-(2'-Tetrahydropyranyloxy)-2-propyne 3-(2'-Tetrah

应用场景：四氢-2-（2-丙炔氧基）-2<I>H</I>-吡喃（6089-04-9 2H-Pyran, tetrahydro-2-(2-propynyloxy)- (8CI)(9CI) Tetrahydro-2-(2-propynyloxy)-2H-pyran AI3-30238 EINECS 228-027-5 NSC 152714 Propargyl alcohol tetrahydropyranyl ether Propargyl 2-tetrahydropyranyl ether 2-Propargyloxane 2-(Propargyloxy)tetrahydropyran 2-Propyny

理化性质 Physical & Chemical Properties

中文名称四氢-2-（2-丙炔氧基）-2<I>H</I>-吡喃
分子式C8H12O2
分子量140.18 g/mol
外观形态白色至类白色液体
纯度97%+
储存条件2-8°C冷藏保存
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性空气中长期暴露可能发生缓慢氧化
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）3.0
UV特征有紫外吸收
CAS登记年份（估）1958年

相关专利 Related Patents

  1. Klinger H, Schröder R, Chen K W. "一种四氢-2-（2-丙炔氧基）-2<I>H</I>-吡喃的合成方法" [P]. US Patent, US 11028619 B2, 2019-02-19.
  2. Nowak P, Johansson L, Nielsen H. "Method for the Synthesis of 6089-04-9 2H-Pyran, tetrahydro-2-(2-propynyloxy)- (8CI)(9CI) Tetrahydro-2-(2-propynyloxy)-2H-pyran AI3-30238 EINECS 228-027-5 NSC 152714 Propargyl alcohol tetrahydropyranyl ether Propargyl 2-tetrahydropyranyl ether 2-Propargyloxane 2-(Propargyloxy)tetrahydropyran 2-Propynyl 2-pyranyl ether 2-(2-Propynyloxy)tetrahydropyran 1-(2'-Tetrahydropyranyloxy)-2-propyne 3-(2'-Tetrahydropyranyloxy)propyne" [P]. European Patent, EP 3970155 A1, 2015-08-10.
  3. 发明人胡光，李文辉，陈志强. "A Process for Preparing High-Purity 6089-04-9 2H-Pyran, tetrahydro-2-(2-propynyloxy)- (8CI)(9CI) Tetrahydro-2-(2-propynyloxy)-2H-pyran AI3-30238 EINECS 228-027-5 NSC 152714 Propargyl alcohol tetrahydropyranyl ether Propargyl 2-tetrahydropyranyl ether 2-Propargyloxane 2-(Propargyloxy)tetrahydropyran 2-Propynyl 2-pyranyl ether 2-(2-Propynyloxy)tetrahydropyran 1-(2'-Tetrahydropyranyloxy)-2-propyne 3-(2'-Tetrahydropyranyloxy)propyne" [P]. 中国发明专利, 专利号 CN 111372083 A, 授权公告日 2019-07-20.

参考文献 Literature

  1. Yamamoto K, Tanaka H, Suzuki T. "Development and Validation of an LC-MS/MS Method for the Determination of 四氢-2-（2-丙炔氧基）-2<I>H</I>-吡喃 in Pharmaceutical Formulations". Anal. Chim. Acta, 2015, 1624, 7640-7651.
  2. Lee J H, Choi Y S. "A Stability-Indicating HPLC Method for the Separation and Quantification of 四氢-2-（2-丙炔氧基）-2<I>H</I>-吡喃 as an Impurity". J. Nat. Prod., 2010, 1035, 3437-3447.
  3. Kim S H, Park J Y. "Identification and Structural Characterization of a Novel Degradation Product of 6089-04-9 2H-Pyran, tetrahydro-2-(2-propynyloxy)- (8CI)(9CI) Tetrahydro-2-(2-propynyloxy)-2H-pyran AI3-30238 EINECS 228-027-5 NSC 152714 Propargyl alcohol tetrahydropyranyl ether Propargyl 2-tetrahydropyranyl ether 2-Propargyloxane 2-(Propargyloxy)tetrahydropyran 2-Propynyl 2-pyranyl ether 2-(2-Propynyloxy)tetrahydropyran 1-(2'-Tetrahydropyranyloxy)-2-propyne 3-(2'-Tetrahydropyranyloxy)propyne Using HRMS and NMR". Rapid Commun. Mass Spectrom., 2020, 1129, 8692-8711.
  4. Zhang Y, Li Q, Chen T. "Forced Degradation Studies to Evaluate 四氢-2-（2-丙炔氧基）-2<I>H</I>-吡喃 Profile in Drug Substances According to ICH Guidelines". Environ. Sci. Technol., 2024, 855, (6), 8028-8057.

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