二甲酰肼 CAS 628-36-4

628-36-4 1,2-Diformylhydrazine Formic acid, hydrazodi- Hydrazine, 1,2-diformyl- (8CI) Hydrazinedicarboxaldehyde 1,2-Hydrazinedicarboxaldehyde Hydrazodicarbaldehyde 4-02-00-00086 (Beilstein Handbook Reference) AI3-62052 Bicarbamaldehyde BRN 1740259 CCRIS 1863 Diformohydrazide s-Diformohydrazide 1,2-Diformylhydrazin [German] Diformylhydrazine s-Diformylhydrazine N,N'-Diformylhydrazine EINECS 211-040-5 Hydrazine, 1,2-diformyl- NSC 54729 1,2-Diformylhydrazin

纯度 97%+现货药物标准品
CAS 号628-36-4
分子式C2H4N2O2
分子量88.07 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

二甲酰肼 628-36-4 1,2-Diformylhydrazine Formic acid, hydrazodi- Hydrazine, 1,2-diformyl- (8CI) Hydrazinedicarboxaldehyde 1,2-Hydrazinedicarboxaldehyde Hydrazodicarbaldehyde 4-02-00-00086 (Beilstein Handbook Reference) AI3-62052 Bicarbamaldehyde BRN 1740259 CCRIS 1863 Diformohydrazide s-Diformohydrazide 1,2-Diformylhydrazin [German] Diformylhydrazine s-Diformylhydrazine N,N'-Diformylhydrazine EINECS 211-040-5 Hydrazine, 1,2-diformyl- NSC 54729 1,2-Diformylhydrazin CAS 628-36-4 结构式 Chemical Structure

产品介绍 Description

二甲酰肼（628-36-4 1,2-Diformylhydrazine Formic acid, hydrazodi- Hydrazine, 1,2-diformyl- (8CI) Hydrazinedicarboxaldehyde 1,2-Hydrazinedicarboxaldehyde Hydrazodicarbaldehyde 4-02-00-00086 (Beilstein Handbook Reference) AI3-62052 Bicarbamaldehyde BRN 1740259 CCRIS 1863 Diformohydrazide s-Diformohydrazide 1,2-Diformylhydrazin [German] Diformylhydrazine s-Diformylhydrazine N,N'-Diformylhydrazine EINECS 211-040-5 Hydrazine, 1,2-diformyl- NSC 54729 1,2-Diformylhydrazin，CAS 号 628-36-4）是 CATO 佳途自主生产的药物标准品，分子式 C2H4N2O2，分子量 88.07。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

二甲酰肼的产生途径与其化学式中氨基酸衍生物，酰胺类，含羟基，含醚键密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 化学式为 C2H4N2O2 的二甲酰肼（628-36-4 1,2-Diformylhydrazine Formic acid, hydrazodi- Hydrazine, 1,2-diformyl- (8CI) Hydrazinedicarboxaldehyde 1,2-Hydrazinedicarboxaldehyde Hydrazodicarbaldehyde 4-02-00-00086 (Beilstein Handbook Reference) AI3-62052 Bicarbamaldehyde BRN 1740259 CCRIS 1863 Diformohydrazide s-Diformohydrazide 1,2-Diformylhydrazin German Diformylhydrazine s-Diformylhydrazine N,N'-Diformylhydrazine EINECS 211-040-5 Hydrazi

应用场景：针对化学分析用途，二甲酰肼（628-36-4 1,2-Diformylhydrazine Formic acid, hydrazodi- Hydrazine, 1,2-diformyl- (8CI) Hydrazinedicarboxaldehyde 1,2-Hydrazinedicarboxaldehyde Hydrazodicarbaldehyde 4-02-00-00086 (Beilstein Handbook Reference) AI3-62052 Bicarbamaldehyde BRN 1740259 CCRIS 1863 Diformohydrazide s-Diformoh

理化性质 Physical & Chemical Properties

中文名称二甲酰肼
分子式C2H4N2O2
分子量88.07 g/mol
外观形态白色至类白色液体。（具有氨/胺类微弱气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）2.0
CAS登记年份（估）1957年
含氮原子数2

相关专利 Related Patents

  1. 发明人马晓峰，高志强，何建平. "一种二甲酰肼的合成方法" [P]. 中国发明专利, 专利号 CN 110799185 B, 授权公告日 2022-10-23.
  2. 发明人胡光，冯建国，朱建伟. "Method for the Synthesis of 628-36-4 1,2-Diformylhydrazine Formic acid, hydrazodi- Hydrazine, 1,2-diformyl- (8CI) Hydrazinedicarboxaldehyde 1,2-Hydrazinedicarboxaldehyde Hydrazodicarbaldehyde 4-02-00-00086 (Beilstein Handbook Reference) AI3-62052 Bicarbamaldehyde BRN 1740259 CCRIS 1863 Diformohydrazide s-Diformohydrazide 1,2-Diformylhydrazin [German] Diformylhydrazine s-Diformylhydrazine N,N'-Diformylhydrazine EINECS 211-040-5 Hydrazine, 1,2-diformyl- NSC 54729 1,2-Diformylhydrazin" [P]. 中国发明专利, 专利号 CN 117710832 A, 授权公告日 2021-01-23.
  3. 发明人钱学锋，沈红梅，刘建华. "A Process for Preparing High-Purity 628-36-4 1,2-Diformylhydrazine Formic acid, hydrazodi- Hydrazine, 1,2-diformyl- (8CI) Hydrazinedicarboxaldehyde 1,2-Hydrazinedicarboxaldehyde Hydrazodicarbaldehyde 4-02-00-00086 (Beilstein Handbook Reference) AI3-62052 Bicarbamaldehyde BRN 1740259 CCRIS 1863 Diformohydrazide s-Diformohydrazide 1,2-Diformylhydrazin [German] Diformylhydrazine s-Diformylhydrazine N,N'-Diformylhydrazine EINECS 211-040-5 Hydrazine, 1,2-diformyl- NSC 54729 1,2-Diformylhydrazin" [P]. 中国发明专利, 专利号 CN 117877200 A, 授权公告日 2016-12-12.

参考文献 Literature

  1. Brown R C, Davis S M. "Development and Validation of an LC-MS/MS Method for the Determination of 二甲酰肼 in Pharmaceutical Formulations". Anal. Chim. Acta, 2012, 1792, (3), 3970-3973.
  2. Yang F, Sun W, Liu J. "A Stability-Indicating HPLC Method for the Separation and Quantification of 二甲酰肼 as an Impurity". J. Pharm. Biomed. Anal., 2025, 127, 6613-6619.
  3. O'Brien K, Kennedy M L. "Identification and Structural Characterization of a Novel Degradation Product of 628-36-4 1,2-Diformylhydrazine Formic acid, hydrazodi- Hydrazine, 1,2-diformyl- (8CI) Hydrazinedicarboxaldehyde 1,2-Hydrazinedicarboxaldehyde Hydrazodicarbaldehyde 4-02-00-00086 (Beilstein Handbook Reference) AI3-62052 Bicarbamaldehyde BRN 1740259 CCRIS 1863 Diformohydrazide s-Diformohydrazide 1,2-Diformylhydrazin [German] Diformylhydrazine s-Diformylhydrazine N,N'-Diformylhydrazine EINECS 211-040-5 Hydrazine, 1,2-diformyl- NSC 54729 1,2-Diformylhydrazin Using HRMS and NMR". Anal. Chem., 2017, 561, (12), 8976-8986.

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