4-Acetoxybenzyl alcohol CAS 6309-46-2

6309-46-2 4-acetoxybenzyl alcohol 4-(hydroxymethyl)phenyl acetate 4-(acetyloxy)benzenemethanol p-acetoxybenzyl alcohol acetic acid 4-(hydroxymethyl)phenyl ester CHEBI:156306

纯度 97%+现货药物标准品
CAS 号6309-46-2
分子式C9H16O3
分子量172.22 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

4-Acetoxybenzyl alcohol 6309-46-2 4-acetoxybenzyl alcohol 4-(hydroxymethyl)phenyl acetate 4-(acetyloxy)benzenemethanol p-acetoxybenzyl alcohol acetic acid 4-(hydroxymethyl)phenyl ester CHEBI:156306 CAS 6309-46-2 结构式 Chemical Structure

产品介绍 Description

4-Acetoxybenzyl alcohol（6309-46-2 4-acetoxybenzyl alcohol 4-(hydroxymethyl)phenyl acetate 4-(acetyloxy)benzenemethanol p-acetoxybenzyl alcohol acetic acid 4-(hydroxymethyl)phenyl ester CHEBI:156306）是药物分析与质量控制领域常用的药物标准品，CAS 号 6309-46-2。分子式 C9H16O3，分子量 172.22。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

4-Acetoxybenzyl alcohol（6309-46-2 4-acetoxybenzyl alcohol 4-(hydroxymethyl)phenyl acetate 4-(acetyloxy)benzenemethanol p-acetoxybenzyl alcohol acetic acid 4-(hydroxymethyl)phenyl ester CHEBI:156306），CAS注册编号 6309-46-2，化学分子式为 C9H16O3，分子量 172.22 g/mol。 4-Acetoxybenzyl alcohol（C9H16O3）含有羧酸类，含羟基，含醚键。具有较强的吸湿性，羧基赋予其一定的酸性特征，这些物理化学性质直接决定了其标准溶液的最佳配制方案和储存策略。 在定量分析中，可作为校准标准或内标物使用，适用于多种检测技术平台（UV-Vis, FLD, MS, FID）。 在质量保证方面，4-Acetoxybenzyl alcohol的生产和定值严格遵循ISO 17034:2016（认证标准物质生产者）的要求。纯度定值采用质

应用场景：针对化学分析用途，4-Acetoxybenzyl alcohol（6309-46-2 4-acetoxybenzyl alcohol 4-(hydroxymethyl)phenyl acetate 4-(acetyloxy)benzenemethanol p-acetoxybenzyl alcohol acetic acid 4-(hydroxymethyl)phenyl ester CHEBI:156306）是具有明确定量溯源的认证级对照品。 推荐以4-Acetoxybenzyl alcohol配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇为溶剂配制储备溶液，根据检测

理化性质 Physical & Chemical Properties

中文名称4-Acetoxybenzyl alcohol
分子式C9H16O3
分子量172.22 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，密封防潮
溶解性参考可溶于甲醇、乙醇、DMSO
稳定性具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）2.0
CAS登记年份（估）1958年

相关专利 Related Patents

  1. Nielsen H, Kowalski A, Nowak P. "一种4-Acetoxybenzyl alcohol的合成方法" [P]. European Patent, EP 3142532 A1, 2022-01-15.
  2. Park J H, Kumar R, Schröder R. "Method for the Synthesis of 6309-46-2 4-acetoxybenzyl alcohol 4-(hydroxymethyl)phenyl acetate 4-(acetyloxy)benzenemethanol p-acetoxybenzyl alcohol acetic acid 4-(hydroxymethyl)phenyl ester CHEBI:156306" [P]. US Patent, US 11155045 B2, 2025-06-03.
  3. Thompson G K, Johnson M A, Anderson J P. "A Process for Preparing High-Purity 6309-46-2 4-acetoxybenzyl alcohol 4-(hydroxymethyl)phenyl acetate 4-(acetyloxy)benzenemethanol p-acetoxybenzyl alcohol acetic acid 4-(hydroxymethyl)phenyl ester CHEBI:156306" [P]. US Patent, US 11208031 B2, 2023-10-13.

参考文献 Literature

  1. Yamamoto K, Tanaka H, Suzuki T. "Development and Validation of an LC-MS/MS Method for the Determination of 4-Acetoxybenzyl alcohol in Pharmaceutical Formulations". Talanta, 2022, 1313, 6402-6417.
  2. Kumar A, Sharma P, Patel R S. "A Stability-Indicating HPLC Method for the Separation and Quantification of 4-Acetoxybenzyl alcohol as an Impurity". Chemosphere, 2022, 114, (5), 2198-2205.
  3. Yamamoto K, Tanaka H, Suzuki T. "Identification and Structural Characterization of a Novel Degradation Product of 6309-46-2 4-acetoxybenzyl alcohol 4-(hydroxymethyl)phenyl acetate 4-(acetyloxy)benzenemethanol p-acetoxybenzyl alcohol acetic acid 4-(hydroxymethyl)phenyl ester CHEBI:156306 Using HRMS and NMR". J. Sep. Sci., 2016, 1548, (11), 6608-6630.

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