PAF（来自心脏PC） CAS 65154-06-5

65154-06-5 Platelet activating factor Platelet activating factor phosphatidate Blood platelet-activating factor AGEPC PAF-acether Platelet activating factor-acether Platelet-activating factor 1-O-Alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine Antihypertensive polar renomedullary lipid Blood platelet activating factor - acether

纯度 97%+现货药物标准品
CAS 号65154-06-5
分子式C26H54NO7P
分子量523.68 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

PAF（来自心脏PC） 65154-06-5 Platelet activating factor Platelet activating factor phosphatidate Blood platelet-activating factor AGEPC PAF-acether Platelet activating factor-acether Platelet-activating factor 1-O-Alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine Antihypertensive polar renomedullary lipid Blood platelet activating factor - acether CAS 65154-06-5 结构式 Chemical Structure

产品介绍 Description

PAF（来自心脏PC）（英文名 65154-06-5 Platelet activating factor Platelet activating factor phosphatidate Blood platelet-activating factor AGEPC PAF-acether Platelet activating factor-acether Platelet-activating factor 1-O-Alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine Antihypertensive polar renomedullary lipid Blood platelet activating factor - acether，CAS 65154-06-5）属于药物标准品。分子式 C26H54NO7P，分子量 523.68。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

本品定值报告包含以下质量控制信息： - 主成分含量：97%+； - 水分/残留溶剂：通过卡尔费休（KF）和热重分析（TGA）测定并校正； - 定值方法：HPLC-DAD面积归一化法、qNMR法、DSC法等正交验证； - 不确定度：扩展不确定度（k=2）包含测量重复性、均匀性和稳定性分量。 化学式为 C26H54NO7P 的PAF（来自心脏PC）（65154-06-5 Platelet activating factor Platelet activating factor phosphatidate Blood platelet-activating factor AGEPC PAF-acether Platelet activating factor-acether Platelet-activating factor 1-O-Alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine Antihypertensive polar renomedullary lipid Blood platelet activati

应用场景：PAF（来自心脏PC）（65154-06-5 Platelet activating factor Platelet activating factor phosphatidate Blood platelet-activating factor AGEPC PAF-acether Platelet activating factor-acether Platelet-activating factor 1-O-Alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine Antihypertensive polar renomedullary lipid Bl

理化性质 Physical & Chemical Properties

中文名称PAF（来自心脏PC）
分子式C26H54NO7P
分子量523.68 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件室温保存，避光，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）0.5
CAS登记年份（估）1975年
含氮原子数1

相关专利 Related Patents

  1. 发明人林芳，王建平，刘建华. "一种PAF（来自心脏PC）的合成方法" [P]. 中国发明专利, 专利号 CN 114304241 B, 授权公告日 2022-06-22.
  2. 发明人罗永刚，何建平，徐明华. "Method for the Synthesis of 65154-06-5 Platelet activating factor Platelet activating factor phosphatidate Blood platelet-activating factor AGEPC PAF-acether Platelet activating factor-acether Platelet-activating factor 1-O-Alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine Antihypertensive polar renomedullary lipid Blood platelet activating factor - acether" [P]. 中国发明专利, 专利号 CN 109695621 B, 授权公告日 2022-11-17.

参考文献 Literature

  1. Hughes D, Roberts J, Thomas A. "Development and Validation of an LC-MS/MS Method for the Determination of PAF（来自心脏PC） in Pharmaceutical Formulations". J. Chromatogr. A, 2012, 944, (12), 1140-1147.
  2. O'Brien K, Kennedy M L. "A Stability-Indicating HPLC Method for the Separation and Quantification of PAF（来自心脏PC） as an Impurity". Sci. Total Environ., 2018, 2439, (12), 1978-1983.
  3. O'Brien K, Kennedy M L. "Identification and Structural Characterization of a Novel Degradation Product of 65154-06-5 Platelet activating factor Platelet activating factor phosphatidate Blood platelet-activating factor AGEPC PAF-acether Platelet activating factor-acether Platelet-activating factor 1-O-Alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine Antihypertensive polar renomedullary lipid Blood platelet activating factor - acether Using HRMS and NMR". J. Pharm. Biomed. Anal., 2024, 149, 6261-6277.
  4. Kowalski T, Nowak Z. "Forced Degradation Studies to Evaluate PAF（来自心脏PC） Profile in Drug Substances According to ICH Guidelines". J. Nat. Prod., 2021, 2174, 4890-4910.

Related Platelet Standards 同系列产品

推荐产品 Recommended Standards

为什么选择 CATO 佳途？

加载产品详情...