2-Fluoro-4-(trifluoromethyl)aniline CAS 69409-98-9

2-FLUORO-4-(TRIFLUORMETHYL)ANILINE 2-FLUORO-4-(TRIFLUOROMETHYL)ANILINE 2-FLUORO-4-(TRIFLUOROMETHYL)BENZENAMINE 2-FLUORO-4-(TRIFLUOROMETHYL)PHENYLAMINE 2-fluoro-4-trifluoromethylaniline 3-FLUORO-4-AMINOBENZOTRIFLUORIDE 4-AMINO-3-FLUOROBENZOTRIFLUORIDE 69409-98-9 PF10425

纯度 97%+现货药物标准品
CAS 号69409-98-9
分子式C7H11F4N
分子量185.16 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

2-Fluoro-4-(trifluoromethyl)aniline 2-FLUORO-4-(TRIFLUORMETHYL)ANILINE 2-FLUORO-4-(TRIFLUOROMETHYL)ANILINE 2-FLUORO-4-(TRIFLUOROMETHYL)BENZENAMINE 2-FLUORO-4-(TRIFLUOROMETHYL)PHENYLAMINE 2-fluoro-4-trifluoromethylaniline 3-FLUORO-4-AMINOBENZOTRIFLUORIDE 4-AMINO-3-FLUOROBENZOTRIFLUORIDE 69409-98-9 PF10425 CAS 69409-98-9 结构式 Chemical Structure

产品介绍 Description

2-Fluoro-4-(trifluoromethyl)aniline（英文名 2-FLUORO-4-(TRIFLUORMETHYL)ANILINE 2-FLUORO-4-(TRIFLUOROMETHYL)ANILINE 2-FLUORO-4-(TRIFLUOROMETHYL)BENZENAMINE 2-FLUORO-4-(TRIFLUOROMETHYL)PHENYLAMINE 2-fluoro-4-trifluoromethylaniline 3-FLUORO-4-AMINOBENZOTRIFLUORIDE 4-AMINO-3-FLUOROBENZOTRIFLUORIDE 69409-98-9 PF10425，CAS 69409-98-9）属于药物标准品。分子式 C7H11F4N，分子量 185.16。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

与同类药物标准品相比，2-Fluoro-4-(trifluoromethyl)aniline的分子量为185.16 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 2-Fluoro-4-(trifluoromethyl)aniline（2-FLUORO-4-(TRIFLUORMETHYL)ANILINE 2-FLUORO-4-(TRIFLUOROMETHYL)ANILINE 2-FLUORO-4-(TRIFLUOROMETHYL)BENZENAMINE 2-FLUORO-4-(TRIFLUOROMETHYL)PHENYLAMINE 2-fluoro-4-trifluoromethylaniline 3-FLUORO-4-AMINOBENZOTRIFLUORIDE 4-AMINO-3-FLUOROBENZOTRIFLUORIDE 69409-98-9 PF10425），CAS注册编号 69409-98-9，化学分子式为 C7H11F4N，分子量 185.16 g/mol。 受分子结构中含氟取代的影响，2-Fluoro-4-(trifluoromethyl)ani

应用场景：2-Fluoro-4-(trifluoromethyl)aniline（2-FLUORO-4-(TRIFLUORMETHYL)ANILINE 2-FLUORO-4-(TRIFLUOROMETHYL)ANILINE 2-FLUORO-4-(TRIFLUOROMETHYL)BENZENAMINE 2-FLUORO-4-(TRIFLUOROMETHYL)PHENYLAMINE 2-fluoro-4-trifluoromethylaniline 3-FLUORO-4-AMINOBENZOTRIFLUORIDE 4-AMINO-3-FLUOROBENZOTRIFLUORIDE 69409-98-9 PF

理化性质 Physical & Chemical Properties

中文名称2-Fluoro-4-(trifluoromethyl)aniline
分子式C7H11F4N
分子量185.16 g/mol
外观形态白色至类白色结晶性粉末。（具有轻微卤代物特征气味，具有氨/胺类微弱气味，挥发性较低）
纯度97%+
储存条件2-8°C冷藏保存，避光，密闭保存防止挥发
溶解性参考可溶于甲醇、乙腈、DMSO
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）1.0
CAS登记年份（估）1976年
卤素含量F取代
含氮原子数1

相关专利 Related Patents

  1. 发明人韩伟，马晓峰，郭海燕. "一种2-Fluoro-4-(trifluoromethyl)aniline的合成方法" [P]. 中国发明专利, 专利号 CN 113492617 A, 授权公告日 2015-09-07.
  2. 发明人胡光，杨光，朱建伟. "Method for the Synthesis of 2-FLUORO-4-(TRIFLUORMETHYL)ANILINE 2-FLUORO-4-(TRIFLUOROMETHYL)ANILINE 2-FLUORO-4-(TRIFLUOROMETHYL)BENZENAMINE 2-FLUORO-4-(TRIFLUOROMETHYL)PHENYLAMINE 2-fluoro-4-trifluoromethylaniline 3-FLUORO-4-AMINOBENZOTRIFLUORIDE 4-AMINO-3-FLUOROBENZOTRIFLUORIDE 69409-98-9 PF10425" [P]. 中国发明专利, 专利号 CN 111825757 A, 授权公告日 2024-12-11.

参考文献 Literature

  1. Brown R C, Davis S M. "Development and Validation of an LC-MS/MS Method for the Determination of 2-Fluoro-4-(trifluoromethyl)aniline in Pharmaceutical Formulations". Food Chem., 2013, 2354, 6282-6304.
  2. Lee J H, Choi Y S. "A Stability-Indicating HPLC Method for the Separation and Quantification of 2-Fluoro-4-(trifluoromethyl)aniline as an Impurity". Chromatographia, 2021, 1831, (2), 4124-4152.
  3. O'Brien K, Kennedy M L. "Identification and Structural Characterization of a Novel Degradation Product of 2-FLUORO-4-(TRIFLUORMETHYL)ANILINE 2-FLUORO-4-(TRIFLUOROMETHYL)ANILINE 2-FLUORO-4-(TRIFLUOROMETHYL)BENZENAMINE 2-FLUORO-4-(TRIFLUOROMETHYL)PHENYLAMINE 2-fluoro-4-trifluoromethylaniline 3-FLUORO-4-AMINOBENZOTRIFLUORIDE 4-AMINO-3-FLUOROBENZOTRIFLUORIDE 69409-98-9 PF10425 Using HRMS and NMR". J. Chromatogr. A, 2021, 779, (11), 5322-5348.
  4. Martinez C, Lopez D R. "Forced Degradation Studies to Evaluate 2-Fluoro-4-(trifluoromethyl)aniline Profile in Drug Substances According to ICH Guidelines". Environ. Sci. Technol., 2014, 1637, (8), 2819-2825.

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