5-(2-Chloro-acetylamino)-3-methyl-thiophene-2,4-dicarboxylic acid 4-ethyl ester 2-(2-methoxy-ethyl) ester CAS 733796-15-1

5-(2-Chloro-acetylamino)-3-methyl-thiophene-2,4-dicarboxylic acid 4-ethyl ester 2-(2-methoxy-ethyl) ester

纯度 97%+现货药物标准品
CAS 号733796-15-1
分子式C14H18ClNO6S
分子量363.81 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

5-(2-Chloro-acetylamino)-3-methyl-thiophene-2,4-dicarboxylic acid 4-ethyl ester 2-(2-methoxy-ethyl) ester 5-(2-Chloro-acetylamino)-3-methyl-thiophene-2,4-dicarboxylic acid 4-ethyl ester 2-(2-methoxy-ethyl) ester CAS 733796-15-1 结构式 Chemical Structure

产品介绍 Description

5-(2-Chloro-acetylamino)-3-methyl-thiophene-2,4-dicarboxylic acid 4-ethyl ester 2-(2-methoxy-ethyl) ester（英文名 5-(2-Chloro-acetylamino)-3-methyl-thiophene-2,4-dicarboxylic acid 4-ethyl ester 2-(2-methoxy-ethyl) ester，CAS 733796-15-1）属于药物标准品。分子式 C14H18ClNO6S，分子量 363.81。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

5-(2-Chloro-acetylamino)-3-methyl-thiophene-2,4-dicarboxylic acid 4-ethyl ester 2-(2-methoxy-ethyl) ester的产生途径与其化学式中含氮杂环结构，酰胺类，含砜基，含羟基，含醚键，含氯取代密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 5-(2-Chloro-acetylamino)-3-methyl-thiophene-2,4-dicarboxylic acid 4-ethyl ester 2-(2-methoxy-ethyl) ester（5-(2-Chloro-acetylamino)-3-methyl-thiophene-2,4-dicarboxylic acid 4-ethyl ester 2-(2-methoxy-ethyl) ester），CAS注册编号 733796-15-1，化学分子式为 C14H18ClNO6S，分子量 363.81 g/mol。 5-(2-Chloro-acetylamino)-3-methyl-thiophene-2,4-

应用场景：5-(2-Chloro-acetylamino)-3-methyl-thiophene-2,4-dicarboxylic acid 4-ethyl ester 2-(2-methoxy-ethyl) ester（5-(2-Chloro-acetylamino)-3-methyl-thiophene-2,4-dicarboxylic acid 4-ethyl ester 2-(2-methoxy-ethyl) ester，CAS 733796-15-1）的标准化应用场景涵盖化学分析等多个专业技术领域。 推荐以5-(2-Chloro-acetylamino)-3-methyl-thiophene

理化性质 Physical & Chemical Properties

中文名称5-(2-Chloro-acetylamino)-3-methyl-thiophene-2,4-dicarboxylic acid 4-ethyl ester 2-(2-methoxy-ethyl) ester
分子式C14H18ClNO6S
分子量363.81 g/mol
外观形态类白色至淡黄色结晶性粉末。（具有轻微卤代物特征气味，含硫化合物特征性气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封；含酯键，遇强碱易水解
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）6.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1986年
卤素含量Cl取代
含氮原子数1
含硫原子数1

相关专利 Related Patents

  1. 发明人郭海燕，黄志刚，林芳. "一种5-(2-Chloro-acetylamino)-3-methyl-thiophene-2,4-dicarboxylic acid 4-ethyl ester 2-(2-methoxy-ethyl) ester的合成方法" [P]. 中国发明专利, 专利号 CN 114953129 A, 授权公告日 2018-06-02.
  2. 发明人杨光，胡光，唐晓军. "Method for the Synthesis of 5-(2-Chloro-acetylamino)-3-methyl-thiophene-2,4-dicarboxylic acid 4-ethyl ester 2-(2-methoxy-ethyl) ester" [P]. 中国发明专利, 专利号 CN 111975000 A, 授权公告日 2020-08-16.
  3. 发明人周伟，张德明，沈红梅. "A Process for Preparing High-Purity 5-(2-Chloro-acetylamino)-3-methyl-thiophene-2,4-dicarboxylic acid 4-ethyl ester 2-(2-methoxy-ethyl) ester" [P]. 中国发明专利, 专利号 CN 111984724 A, 授权公告日 2024-11-25.

参考文献 Literature

  1. Garcia M, Rodriguez P. "Development and Validation of an LC-MS/MS Method for the Determination of 5-(2-Chloro-acetylamino)-3-methyl-thiophene-2,4-dicarboxylic acid 4-ethyl ester 2-(2-methoxy-ethyl) ester in Pharmaceutical Formulations". Phytochemistry, 2013, 1824, 2467-2488.
  2. Yamamoto K, Tanaka H, Suzuki T. "A Stability-Indicating HPLC Method for the Separation and Quantification of 5-(2-Chloro-acetylamino)-3-methyl-thiophene-2,4-dicarboxylic acid 4-ethyl ester 2-(2-methoxy-ethyl) ester as an Impurity". J. Sep. Sci., 2023, 104, 1588-1609.

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