2-Mercapto-3-(2-methoxy-5-methyl-phenyl)-5,6-dimethyl-3H-thieno[2,3-d]pyrimidin-4-one CAS 734542-99-5

2-Mercapto-3-(2-methoxy-5-methyl-phenyl)-5,6-dimethyl-3H-thieno[2,3-d]pyrimidin-4-one

纯度 97%+现货药物标准品
CAS 号734542-99-5
分子式C16H16N2O2S2
分子量332.44 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

2-Mercapto-3-(2-methoxy-5-methyl-phenyl)-5,6-dimethyl-3H-thieno[2,3-d]pyrimidin-4-one 2-Mercapto-3-(2-methoxy-5-methyl-phenyl)-5,6-dimethyl-3H-thieno[2,3-d]pyrimidin-4-one CAS 734542-99-5 结构式 Chemical Structure

产品介绍 Description

2-Mercapto-3-(2-methoxy-5-methyl-phenyl)-5,6-dimethyl-3H-thieno[2,3-d]pyrimidin-4-one（2-Mercapto-3-(2-methoxy-5-methyl-phenyl)-5,6-dimethyl-3H-thieno[2,3-d]pyrimidin-4-one）是药物分析与质量控制领域常用的药物标准品，CAS 号 734542-99-5。分子式 C16H16N2O2S2，分子量 332.44。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

从化学结构特征来看，2-Mercapto-3-(2-methoxy-5-methyl-phenyl)-5,6-dimethyl-3H-thieno2,3-dpyrimidin-4-one的分子骨架中包含含氮杂环结构，酰胺类，含砜基，含羟基，含醚键。该化合物的不饱和度为10.0，表明结构中存在约10个环或双键等价单元。分子量为332.44 g/mol，属于较高分子量化合物。分子中的氮原子赋予该化合物一定的碱性特征，在酸性流动相条件下可被有效质子化。 2-Mercapto-3-(2-methoxy-5-methyl-phenyl)-5,6-dimethyl-3H-thieno2,3-dpyrimidin-4-one（2-Mercapto-3-(2-methoxy-5-methyl-phenyl)-5,6-dimethyl-3H-thieno2,3-dpyrimidin-4-one），CAS注册编号 734542-99-5，化学分子式为 C16H16N2O2S2，分子量 332.44 g/mol。 本品适用于HPLC、GC、LC-MS/MS、GC-MS等主要色谱平台的

应用场景：2-Mercapto-3-(2-methoxy-5-methyl-phenyl)-5,6-dimethyl-3H-thieno 2,3-d pyrimidin-4-one（2-Mercapto-3-(2-methoxy-5-methyl-phenyl)-5,6-dimethyl-3H-thieno 2,3-d pyrimidin-4-one）作为药物标准品，在化学分析分析领域承担着重要的角色。 推荐以2-Mercapto-3-(2-methoxy-5-methyl-phenyl)-5,6-dimethyl-3H-thieno 2,3-d pyrimidin-4-one配制标准系列工作溶液，用

理化性质 Physical & Chemical Properties

中文名称2-Mercapto-3-(2-methoxy-5-methyl-phenyl)-5,6-dimethyl-3H-thieno[2,3-d]pyrimidin-4-one
分子式C16H16N2O2S2
分子量332.44 g/mol
外观形态淡黄色至黄色结晶性粉末。（含硫化合物特征性气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）10.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1986年
含氮原子数2
含硫原子数2

相关专利 Related Patents

  1. Thompson G K, Roberts E F, Johnson M A. "一种2-Mercapto-3-(2-methoxy-5-methyl-phenyl)-5,6-dimethyl-3H-thieno[2,3-d]pyrimidin-4-one的合成方法" [P]. US Patent, US 10709606 B2, 2024-11-23.
  2. Roberts E F, Davis P L, Hughes D C. "Method for the Synthesis of 2-Mercapto-3-(2-methoxy-5-methyl-phenyl)-5,6-dimethyl-3H-thieno[2,3-d]pyrimidin-4-one" [P]. US Patent, US 9456856 B2, 2018-12-15.

参考文献 Literature

  1. Kumar A, Sharma P, Patel R S. "Development and Validation of an LC-MS/MS Method for the Determination of 2-Mercapto-3-(2-methoxy-5-methyl-phenyl)-5,6-dimethyl-3H-thieno[2,3-d]pyrimidin-4-one in Pharmaceutical Formulations". J. Agric. Food Chem., 2015, 2238, (11), 396-413.
  2. Wang L, Li J, Zhang H. "A Stability-Indicating HPLC Method for the Separation and Quantification of 2-Mercapto-3-(2-methoxy-5-methyl-phenyl)-5,6-dimethyl-3H-thieno[2,3-d]pyrimidin-4-one as an Impurity". J. Nat. Prod., 2021, 1621, 1685-1704.
  3. O'Brien K, Kennedy M L. "Identification and Structural Characterization of a Novel Degradation Product of 2-Mercapto-3-(2-methoxy-5-methyl-phenyl)-5,6-dimethyl-3H-thieno[2,3-d]pyrimidin-4-one Using HRMS and NMR". Biomed. Chromatogr., 2021, 555, 3146-3167.
  4. Mueller T, Schmidt R K. "Forced Degradation Studies to Evaluate 2-Mercapto-3-(2-methoxy-5-methyl-phenyl)-5,6-dimethyl-3H-thieno[2,3-d]pyrimidin-4-one Profile in Drug Substances According to ICH Guidelines". J. Chromatogr. A, 2022, 890, (5), 438-447.

Related Mercapto Standards 同系列产品

推荐产品 Recommended Standards

为什么选择 CATO 佳途？

加载产品详情...