<I>R</I>-Alpine-Borane<SUP>®</SUP> 溶液 CAS 73624-47-2

3-pinanyl-9-borabicyclo[3.3.1]nonane 73624-47-2 B-(3-pinanyl)-9-borabicyclo[3.3.1]nonane B-3-pinanyl-9-borabicyclo<3.3.1>nonane B-3-pinanyl-9-borabicyclo[3.3.1]nonane B-3-pinanyl-9-boracyclo<3.3.1>nonane B-3-pinnanyl-9-borobicyclo<3.3.1>nonane B-Ipc-9-BBN

纯度 97%+现货药物标准品
CAS 号73624-47-2
分子式C18H31B
分子量258.25 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

<I>R</I>-Alpine-Borane<SUP>®</SUP> 溶液 3-pinanyl-9-borabicyclo[3.3.1]nonane 73624-47-2 B-(3-pinanyl)-9-borabicyclo[3.3.1]nonane B-3-pinanyl-9-borabicyclo<3.3.1>nonane B-3-pinanyl-9-borabicyclo[3.3.1]nonane B-3-pinanyl-9-boracyclo<3.3.1>nonane B-3-pinnanyl-9-borobicyclo<3.3.1>nonane B-Ipc-9-BBN CAS 73624-47-2 结构式 Chemical Structure

产品介绍 Description

<I>R</I>-Alpine-Borane<SUP>®</SUP> 溶液（英文名 3-pinanyl-9-borabicyclo[3.3.1]nonane 73624-47-2 B-(3-pinanyl)-9-borabicyclo[3.3.1]nonane B-3-pinanyl-9-borabicyclo<3.3.1>nonane B-3-pinanyl-9-borabicyclo[3.3.1]nonane B-3-pinanyl-9-boracyclo<3.3.1>nonane B-3-pinnanyl-9-borobicyclo<3.3.1>nonane B-Ipc-9-BBN，CAS 73624-47-2）属于药物标准品。分子式 C18H31B，分子量 258.25。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

在质量保证方面，<I>R</I>-Alpine-Borane<SUP>®</SUP> 溶液的生产和定值严格遵循ISO 17034:2016（认证标准物质生产者）的要求。纯度定值采用质量平衡法和定量核磁共振（qNMR）等多种正交方法进行交叉验证，扩展不确定度报告为95%置信水平（k=2）。每个批次的均匀性和稳定性均经过独立的统计评估。 <I>R</I>-Alpine-Borane<SUP>®</SUP> 溶液（3-pinanyl-9-borabicyclo3.3.1nonane 73624-47-2 B-(3-pinanyl)-9-borabicyclo3.3.1nonane B-3-pinanyl-9-borabicyclo<3.3.1>nonane B-3-pinanyl-9-borabicyclo3.3.1nonane B-3-pinanyl-9-boracyclo<3.3.1>nonane B-3-pinnanyl-9-borobicyclo<3.3.1>nonane B-Ipc-9-BBN），CAS注册编号 73624-47-2，化学分子式

应用场景：针对化学分析用途，<I>R</I>-Alpine-Borane<SUP>®</SUP> 溶液（3-pinanyl-9-borabicyclo 3.3.1 nonane 73624-47-2 B-(3-pinanyl)-9-borabicyclo 3.3.1 nonane B-3-pinanyl-9-borabicyclo<3.3.1>nonane B-3-pinanyl-9-borabicyclo 3.3.1 nonane B-3-pinanyl-9-boracyclo<3.3.1>nonane B-3-pinnanyl-9-borobicyclo<3.3.1>nonane B-Ipc-9-B

理化性质 Physical & Chemical Properties

中文名称<I>R</I>-Alpine-Borane<SUP>®</SUP> 溶液
分子式C18H31B
分子量258.25 g/mol
外观形态白色至类白色低熔点固体
纯度97%+
储存条件室温保存
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯
稳定性在推荐条件下性质稳定
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）3.5
UV特征有紫外吸收
CAS登记年份（估）1978年

相关专利 Related Patents

  1. 发明人韩伟，朱建伟，钱学锋. "一种<I>R</I>-Alpine-Borane<SUP>®</SUP> 溶液的合成方法" [P]. 中国发明专利, 专利号 CN 113774216 B, 授权公告日 2024-12-14.
  2. Johansson L, Schröder R, Nowak P. "Method for the Synthesis of 3-pinanyl-9-borabicyclo[3.3.1]nonane 73624-47-2 B-(3-pinanyl)-9-borabicyclo[3.3.1]nonane B-3-pinanyl-9-borabicyclo<3.3.1>nonane B-3-pinanyl-9-borabicyclo[3.3.1]nonane B-3-pinanyl-9-boracyclo<3.3.1>nonane B-3-pinnanyl-9-borobicyclo<3.3.1>nonane B-Ipc-9-BBN" [P]. European Patent, EP 3530219 A1, 2016-08-06.

参考文献 Literature

  1. Zhou X P, Huang L, Wu G. "Development and Validation of an LC-MS/MS Method for the Determination of <I>R</I>-Alpine-Borane<SUP>®</SUP> 溶液 in Pharmaceutical Formulations". Phytochemistry, 2022, 518, (9), 5601-5622.
  2. Fischer P, Wagner E. "A Stability-Indicating HPLC Method for the Separation and Quantification of <I>R</I>-Alpine-Borane<SUP>®</SUP> 溶液 as an Impurity". Food Chem., 2011, 870, 5388-5405.
  3. O'Brien K, Kennedy M L. "Identification and Structural Characterization of a Novel Degradation Product of 3-pinanyl-9-borabicyclo[3.3.1]nonane 73624-47-2 B-(3-pinanyl)-9-borabicyclo[3.3.1]nonane B-3-pinanyl-9-borabicyclo<3.3.1>nonane B-3-pinanyl-9-borabicyclo[3.3.1]nonane B-3-pinanyl-9-boracyclo<3.3.1>nonane B-3-pinnanyl-9-borobicyclo<3.3.1>nonane B-Ipc-9-BBN Using HRMS and NMR". J. Sep. Sci., 2021, 1661, 6239-6260.
  4. Garcia M, Rodriguez P. "Forced Degradation Studies to Evaluate <I>R</I>-Alpine-Borane<SUP>®</SUP> 溶液 Profile in Drug Substances According to ICH Guidelines". J. Pharm. Biomed. Anal., 2012, 696, (11), 4709-4720.

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