C18-02:0 PC CAS 74389-69-8

(-)-1-O-octadeyl-2-O-acetyl-sn-glycerylphosphocholine (2R)-2-acetoxy-3-(octadecyloxy)propyl 2-(trimethylammonio)ethyl phosphate (2RR)-2-acetoxy-3-(octadecyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate (R)-7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphaheptaconasan-1-aminium hydroxide inner salt 4-oxide 1-0-octadecyl 2-0-acetyl sn-glycero-3-phosphorylcholine 1-O-Stearoyl-2-acetyl-sn-glyceryl-3-phosphorylcholine 1-O-Stearyl-2-acetyl-sn-glyceryl-3-phosphorylcholine 1-O-octadecyl 2-O-acetyl sn-glycero-3-phosphorylcholine 1-O-octadecyl-2-O-acetyl-sn-glycero-3-phosphocholine 1-O-octadecyl-2-O-acetyl-sn-glyceryl-3-phosphorylcholine 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine 1-O-octadecyl-2-acetyl-sn-glyceryl-3-phosphorylcholine 1-O-octadecyl-PAF 1-O-octadecyl-platelet-activating factor 1-octadecyl-2-acetyl-sn-glycero-3-phosphocholine 2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine 74389-69-8 AGEPC Blood platelet activating factor-aether Blood platelet-activating factor C18-PAF C18-PAF-acether C18:0 PAF CHEBI:52450 PAF PAF acether PAF-acether PC(O-18:0/2:0) Ro 14-8161 acetyl-glyceryl-ether-phosphorylcholine blood platelet activating factor-acether phosphatidylcholine (O-18:0/2:0) platelet activating factor platelet activating factor-acether platelet-activating factor

纯度 97%+现货药物标准品
CAS 号74389-69-8
分子式C28H58NO7P
分子量551.74 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

C18-02:0 PC (-)-1-O-octadeyl-2-O-acetyl-sn-glycerylphosphocholine (2R)-2-acetoxy-3-(octadecyloxy)propyl 2-(trimethylammonio)ethyl phosphate (2RR)-2-acetoxy-3-(octadecyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate (R)-7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphaheptaconasan-1-aminium hydroxide inner salt 4-oxide 1-0-octadecyl 2-0-acetyl sn-glycero-3-phosphorylcholine 1-O-Stearoyl-2-acetyl-sn-glyceryl-3-phosphorylcholine 1-O-Stearyl-2-acetyl-sn-glyceryl-3-phosphorylcholine 1-O-octadecyl 2-O-acetyl sn-glycero-3-phosphorylcholine 1-O-octadecyl-2-O-acetyl-sn-glycero-3-phosphocholine 1-O-octadecyl-2-O-acetyl-sn-glyceryl-3-phosphorylcholine 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine 1-O-octadecyl-2-acetyl-sn-glyceryl-3-phosphorylcholine 1-O-octadecyl-PAF 1-O-octadecyl-platelet-activating factor 1-octadecyl-2-acetyl-sn-glycero-3-phosphocholine 2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine 74389-69-8 AGEPC Blood platelet activating factor-aether Blood platelet-activating factor C18-PAF C18-PAF-acether C18:0 PAF CHEBI:52450 PAF PAF acether PAF-acether PC(O-18:0/2:0) Ro 14-8161 acetyl-glyceryl-ether-phosphorylcholine blood platelet activating factor-acether phosphatidylcholine (O-18:0/2:0) platelet activating factor platelet activating factor-acether platelet-activating factor CAS 74389-69-8 结构式 Chemical Structure

产品介绍 Description

C18-02:0 PC（(-)-1-O-octadeyl-2-O-acetyl-sn-glycerylphosphocholine (2R)-2-acetoxy-3-(octadecyloxy)propyl 2-(trimethylammonio)ethyl phosphate (2RR)-2-acetoxy-3-(octadecyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate (R)-7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphaheptaconasan-1-aminium hydroxide inner salt 4-oxide 1-0-octadecyl 2-0-acetyl sn-glycero-3-phosphorylcholine 1-O-Stearoyl-2-acetyl-sn-glyceryl-3-phosphorylcholine 1-O-Stearyl-2-acetyl-sn-glyceryl-3-phosphorylcholine 1-O-octadecyl 2-O-acetyl sn-glycero-3-phosphorylcholine 1-O-octadecyl-2-O-acetyl-sn-glycero-3-phosphocholine 1-O-octadecyl-2-O-acetyl-sn-glyceryl-3-phosphorylcholine 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine 1-O-octadecyl-2-acetyl-sn-glyceryl-3-phosphorylcholine 1-O-octadecyl-PAF 1-O-octadecyl-platelet-activating factor 1-octadecyl-2-acetyl-sn-glycero-3-phosphocholine 2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine 74389-69-8 AGEPC Blood platelet activating factor-aether Blood platelet-activating factor C18-PAF C18-PAF-acether C18:0 PAF CHEBI:52450 PAF PAF acether PAF-acether PC(O-18:0/2:0) Ro 14-8161 acetyl-glyceryl-ether-phosphorylcholine blood platelet activating factor-acether phosphatidylcholine (O-18:0/2:0) platelet activating factor platelet activating factor-acether platelet-activating factor，CAS 号 74389-69-8）是 CATO 佳途自主生产的药物标准品，分子式 C28H58NO7P，分子量 551.74。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

本品适用于HPLC、GC、LC-MS/MS、GC-MS等主要色谱平台的定量分析，可作为外标法校准标准品或系统适用性测试参考物质使用。 C18-02:0 PC（(-)-1-O-octadeyl-2-O-acetyl-sn-glycerylphosphocholine (2R)-2-acetoxy-3-(octadecyloxy)propyl 2-(trimethylammonio)ethyl phosphate (2RR)-2-acetoxy-3-(octadecyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate (R)-7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphaheptaconasan-1-aminium hydroxide inner salt 4-oxide 1-0-octadecyl 2-0-acetyl sn-glycero-3-phosphorylcholine 1-O-Stearoyl-2-acetyl-sn-glyc

应用场景：针对化学分析用途，C18-02:0 PC（(-)-1-O-octadeyl-2-O-acetyl-sn-glycerylphosphocholine (2R)-2-acetoxy-3-(octadecyloxy)propyl 2-(trimethylammonio)ethyl phosphate (2RR)-2-acetoxy-3-(octadecyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate (R)-7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphaheptacon

理化性质 Physical & Chemical Properties

中文名称C18-02:0 PC
分子式C28H58NO7P
分子量551.74 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件室温保存，避光，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）0.5
CAS登记年份（估）1978年
含氮原子数1

相关专利 Related Patents

  1. Yamamoto T, Anderson J P, Patel M V. "一种C18-02:0 PC的合成方法" [P]. US Patent, US 9853549 B2, 2021-01-12.
  2. O'Brien P Q, Anderson J P, Davis P L. "Method for the Synthesis of (-)-1-O-octadeyl-2-O-acetyl-sn-glycerylphosphocholine (2R)-2-acetoxy-3-(octadecyloxy)propyl 2-(trimethylammonio)ethyl phosphate (2RR)-2-acetoxy-3-(octadecyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate (R)-7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphaheptaconasan-1-aminium hydroxide inner salt 4-oxide 1-0-octadecyl 2-0-acetyl sn-glycero-3-phosphorylcholine 1-O-Stearoyl-2-acetyl-sn-glyceryl-3-phosphorylcholine 1-O-Stearyl-2-acetyl-sn-glyceryl-3-phosphorylcholine 1-O-octadecyl 2-O-acetyl sn-glycero-3-phosphorylcholine 1-O-octadecyl-2-O-acetyl-sn-glycero-3-phosphocholine 1-O-octadecyl-2-O-acetyl-sn-glyceryl-3-phosphorylcholine 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine 1-O-octadecyl-2-acetyl-sn-glyceryl-3-phosphorylcholine 1-O-octadecyl-PAF 1-O-octadecyl-platelet-activating factor 1-octadecyl-2-acetyl-sn-glycero-3-phosphocholine 2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine 74389-69-8 AGEPC Blood platelet activating factor-aether Blood platelet-activating factor C18-PAF C18-PAF-acether C18:0 PAF CHEBI:52450 PAF PAF acether PAF-acether PC(O-18:0/2:0) Ro 14-8161 acetyl-glyceryl-ether-phosphorylcholine blood platelet activating factor-acether phosphatidylcholine (O-18:0/2:0) platelet activating factor platelet activating factor-acether platelet-activating factor" [P]. US Patent, US 9258271 B2, 2023-09-21.
  3. 发明人黄志刚，唐晓军，赵玉洁. "A Process for Preparing High-Purity (-)-1-O-octadeyl-2-O-acetyl-sn-glycerylphosphocholine (2R)-2-acetoxy-3-(octadecyloxy)propyl 2-(trimethylammonio)ethyl phosphate (2RR)-2-acetoxy-3-(octadecyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate (R)-7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphaheptaconasan-1-aminium hydroxide inner salt 4-oxide 1-0-octadecyl 2-0-acetyl sn-glycero-3-phosphorylcholine 1-O-Stearoyl-2-acetyl-sn-glyceryl-3-phosphorylcholine 1-O-Stearyl-2-acetyl-sn-glyceryl-3-phosphorylcholine 1-O-octadecyl 2-O-acetyl sn-glycero-3-phosphorylcholine 1-O-octadecyl-2-O-acetyl-sn-glycero-3-phosphocholine 1-O-octadecyl-2-O-acetyl-sn-glyceryl-3-phosphorylcholine 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine 1-O-octadecyl-2-acetyl-sn-glyceryl-3-phosphorylcholine 1-O-octadecyl-PAF 1-O-octadecyl-platelet-activating factor 1-octadecyl-2-acetyl-sn-glycero-3-phosphocholine 2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine 74389-69-8 AGEPC Blood platelet activating factor-aether Blood platelet-activating factor C18-PAF C18-PAF-acether C18:0 PAF CHEBI:52450 PAF PAF acether PAF-acether PC(O-18:0/2:0) Ro 14-8161 acetyl-glyceryl-ether-phosphorylcholine blood platelet activating factor-acether phosphatidylcholine (O-18:0/2:0) platelet activating factor platelet activating factor-acether platelet-activating factor" [P]. 中国发明专利, 专利号 CN 109945772 B, 授权公告日 2018-05-03.

参考文献 Literature

  1. Martinez C, Lopez D R. "Development and Validation of an LC-MS/MS Method for the Determination of C18-02:0 PC in Pharmaceutical Formulations". J. Sep. Sci., 2012, 1211, 5780-5796.
  2. Wang L, Li J, Zhang H. "A Stability-Indicating HPLC Method for the Separation and Quantification of C18-02:0 PC as an Impurity". Biomed. Chromatogr., 2013, 1968, 6124-6142.
  3. Brown R C, Davis S M. "Identification and Structural Characterization of a Novel Degradation Product of (-)-1-O-octadeyl-2-O-acetyl-sn-glycerylphosphocholine (2R)-2-acetoxy-3-(octadecyloxy)propyl 2-(trimethylammonio)ethyl phosphate (2RR)-2-acetoxy-3-(octadecyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate (R)-7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphaheptaconasan-1-aminium hydroxide inner salt 4-oxide 1-0-octadecyl 2-0-acetyl sn-glycero-3-phosphorylcholine 1-O-Stearoyl-2-acetyl-sn-glyceryl-3-phosphorylcholine 1-O-Stearyl-2-acetyl-sn-glyceryl-3-phosphorylcholine 1-O-octadecyl 2-O-acetyl sn-glycero-3-phosphorylcholine 1-O-octadecyl-2-O-acetyl-sn-glycero-3-phosphocholine 1-O-octadecyl-2-O-acetyl-sn-glyceryl-3-phosphorylcholine 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine 1-O-octadecyl-2-acetyl-sn-glyceryl-3-phosphorylcholine 1-O-octadecyl-PAF 1-O-octadecyl-platelet-activating factor 1-octadecyl-2-acetyl-sn-glycero-3-phosphocholine 2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine 74389-69-8 AGEPC Blood platelet activating factor-aether Blood platelet-activating factor C18-PAF C18-PAF-acether C18:0 PAF CHEBI:52450 PAF PAF acether PAF-acether PC(O-18:0/2:0) Ro 14-8161 acetyl-glyceryl-ether-phosphorylcholine blood platelet activating factor-acether phosphatidylcholine (O-18:0/2:0) platelet activating factor platelet activating factor-acether platelet-activating factor Using HRMS and NMR". Food Chem., 2024, 2154, (5), 408-438.

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