CHAPSO CAS 82473-24-3

3-[(3-Cholamidopropyl)-dimethyl-ammonio]-2-hydroxy-1-propane sulfonate 3-[(3-micro degrees .+/-u>>u) paragraph signthorn(1/4)x>>u degrees +/->>u]-2-oC>>u-1-+/-u>>CEaAUNI 3-[dimethyl({3-[(4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R,16S)-5,9,16-trihydroxy-2,15-dimethyltetracyclo[8.7.0.0?,?.0??,??]heptadecan-14-yl]pentanamido]propyl})ammonio]-2-hydroxypropane-1-sulfonate 82473-24-3

纯度 97%+现货药物标准品
CAS 号82473-24-3
分子式C32H58N2O8S
分子量630.88 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

CHAPSO 3-[(3-Cholamidopropyl)-dimethyl-ammonio]-2-hydroxy-1-propane sulfonate 3-[(3-micro degrees .+/-u>>u) paragraph signthorn(1/4)x>>u degrees +/->>u]-2-oC>>u-1-+/-u>>CEaAUNI 3-[dimethyl({3-[(4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R,16S)-5,9,16-trihydroxy-2,15-dimethyltetracyclo[8.7.0.0?,?.0??,??]heptadecan-14-yl]pentanamido]propyl})ammonio]-2-hydroxypropane-1-sulfonate 82473-24-3 CAS 82473-24-3 结构式 Chemical Structure

产品介绍 Description

CHAPSO（英文名 3-[(3-Cholamidopropyl)-dimethyl-ammonio]-2-hydroxy-1-propane sulfonate 3-[(3-micro degrees .+/-u>>u) paragraph signthorn(1/4)x>>u degrees +/->>u]-2-oC>>u-1-+/-u>>CEaAUNI 3-[dimethyl({3-[(4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R,16S)-5,9,16-trihydroxy-2,15-dimethyltetracyclo[8.7.0.0?,?.0??,??]heptadecan-14-yl]pentanamido]propyl})ammonio]-2-hydroxypropane-1-sulfonate 82473-24-3，CAS 82473-24-3）属于药物标准品。分子式 C32H58N2O8S，分子量 630.88。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

本品定值报告包含以下质量控制信息： - 主成分含量：97%+； - 水分/残留溶剂：通过卡尔费休（KF）和热重分析（TGA）测定并校正； - 定值方法：HPLC-DAD面积归一化法、qNMR法、DSC法等正交验证； - 不确定度：扩展不确定度（k=2）包含测量重复性、均匀性和稳定性分量。 CHAPSO（3-(3-Cholamidopropyl)-dimethyl-ammonio-2-hydroxy-1-propane sulfonate 3-(3-micro degrees .+/-u>>u) paragraph signthorn(1/4)x>>u degrees +/->>u-2-oC>>u-1-+/-u>>CEaAUNI 3-dimethyl({3-(4R)-4-(1S,2S,5R,7S,9R,10R,11S,14R,15R,16S)-5,9,16-trihydroxy-2,15-dimethyltetracyclo8.7.0.0?,?.0??,??heptadecan-14-ylpentanamidopropyl})amm

应用场景：CHAPSO（3- (3-Cholamidopropyl)-dimethyl-ammonio -2-hydroxy-1-propane sulfonate 3- (3-micro degrees .+/-u>>u) paragraph signthorn(1/4)x>>u degrees +/->>u -2-oC>>u-1-+/-u>>CEaAUNI 3- dimethyl({3- (4R)-4- (1S,2S,5R,7S,9R,10R,11S,14R,15R,16S)-5,9,16-trihydroxy-2,15-dimethyltetracyclo 8.7.0.0?,?.0??,?? he

理化性质 Physical & Chemical Properties

中文名称CHAPSO
分子式C32H58N2O8S
分子量630.88 g/mol
外观形态类白色至淡黄色无定形粉末。（含硫化合物特征性气味）
纯度97%+
储存条件阴凉处（≤25°C）保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）5.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1980年
含氮原子数2
含硫原子数1

相关专利 Related Patents

  1. Fischer A B, Hughes D C, Johnson M A. "一种CHAPSO的合成方法" [P]. US Patent, US 9710761 B2, 2017-03-28.
  2. 发明人黄志刚，张德明，沈红梅. "Method for the Synthesis of 3-[(3-Cholamidopropyl)-dimethyl-ammonio]-2-hydroxy-1-propane sulfonate 3-[(3-micro degrees .+/-u>>u) paragraph signthorn(1/4)x>>u degrees +/->>u]-2-oC>>u-1-+/-u>>CEaAUNI 3-[dimethyl({3-[(4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R,16S)-5,9,16-trihydroxy-2,15-dimethyltetracyclo[8.7.0.0?,?.0??,??]heptadecan-14-yl]pentanamido]propyl})ammonio]-2-hydroxypropane-1-sulfonate 82473-24-3" [P]. 中国发明专利, 专利号 CN 116284787 A, 授权公告日 2015-01-03.

参考文献 Literature

  1. Zhou X P, Huang L, Wu G. "Development and Validation of an LC-MS/MS Method for the Determination of CHAPSO in Pharmaceutical Formulations". Anal. Chem., 2021, 1514, 3036-3047.
  2. Kowalski T, Nowak Z. "A Stability-Indicating HPLC Method for the Separation and Quantification of CHAPSO as an Impurity". Chromatographia, 2020, 1521, (2), 6573-6597.

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