聚合物键合型 4-(二甲氨基)吡啶 CAS 82942-26-5

4-(Dimethylamino)pyridine, polymer-bound 82942-26-5 DMAP on polystyrene N-Benzyl-4-(methylamino)pyridine, polymer-bound N-Methyl-N-(4-pyridyl)aminomethyl-polystyrene, cross-linked with divinylbenzene inverted exclamation markaDimethylaminopyridine inverted exclamation marka on polystyrene

纯度 97%+现货药物标准品
CAS 号82942-26-5
分子式C6H8N2
分子量108.14 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

聚合物键合型 4-(二甲氨基)吡啶 4-(Dimethylamino)pyridine, polymer-bound 82942-26-5 DMAP on polystyrene N-Benzyl-4-(methylamino)pyridine, polymer-bound N-Methyl-N-(4-pyridyl)aminomethyl-polystyrene, cross-linked with divinylbenzene inverted exclamation markaDimethylaminopyridine inverted exclamation marka on polystyrene CAS 82942-26-5 结构式 Chemical Structure

产品介绍 Description

本产品为药物标准品聚合物键合型 4-(二甲氨基)吡啶（4-(Dimethylamino)pyridine, polymer-bound 82942-26-5 DMAP on polystyrene N-Benzyl-4-(methylamino)pyridine, polymer-bound N-Methyl-N-(4-pyridyl)aminomethyl-polystyrene, cross-linked with divinylbenzene inverted exclamation markaDimethylaminopyridine inverted exclamation marka on polystyrene，CAS 82942-26-5），分子式 C6H8N2，分子量 108.14。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。

聚合物键合型 4-(二甲氨基)吡啶的产生途径与其化学式中含氰基密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 CAS编号 82942-26-5 对应的化合物聚合物键合型 4-(二甲氨基)吡啶（英文标识 4-(Dimethylamino)pyridine, polymer-bound 82942-26-5 DMAP on polystyrene N-Benzyl-4-(methylamino)pyridine, polymer-bound N-Methyl-N-(4-pyridyl)aminomethyl-polystyrene, cross-linked with divinylbenzene inverted exclamation markaDimethylaminopyridine inverted exclamation marka on polystyrene），化学式 C6H8N2，相对分子质量 108.14。 受分子结构中含氰基的影响，聚合物键合型 4-(二甲氨基)吡啶表现为类白色至淡黄色液体。（具有氨/胺类微弱气味）。其固体形态的物理化学属性

应用场景：聚合物键合型 4-(二甲氨基)吡啶（4-(Dimethylamino)pyridine, polymer-bound 82942-26-5 DMAP on polystyrene N-Benzyl-4-(methylamino)pyridine, polymer-bound N-Methyl-N-(4-pyridyl)aminomethyl-polystyrene, cross-linked with divinylbenzene inverted exclamation markaDimethylaminopyridine inverted exclamation marka on poly

理化性质 Physical & Chemical Properties

中文名称聚合物键合型 4-(二甲氨基)吡啶
分子式C6H8N2
分子量108.14 g/mol
外观形态类白色至淡黄色液体。（具有氨/胺类微弱气味）
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）4.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1980年
含氮原子数2

相关专利 Related Patents

  1. Anderson J P, Stevens L M, Mueller T. "一种聚合物键合型 4-(二甲氨基)吡啶的合成方法" [P]. US Patent, US 11330814 B2, 2015-06-01.
  2. Nielsen H, Björnsson E, Johansson L. "Method for the Synthesis of 4-(Dimethylamino)pyridine, polymer-bound 82942-26-5 DMAP on polystyrene N-Benzyl-4-(methylamino)pyridine, polymer-bound N-Methyl-N-(4-pyridyl)aminomethyl-polystyrene, cross-linked with divinylbenzene inverted exclamation markaDimethylaminopyridine inverted exclamation marka on polystyrene" [P]. European Patent, EP 3465209 A1, 2015-11-18.

参考文献 Literature

  1. Fischer P, Wagner E. "Development and Validation of an LC-MS/MS Method for the Determination of 聚合物键合型 4-(二甲氨基)吡啶 in Pharmaceutical Formulations". Environ. Sci. Technol., 2013, 2200, 4527-4541.
  2. Xu M, Hu Y, Zhou D. "A Stability-Indicating HPLC Method for the Separation and Quantification of 聚合物键合型 4-(二甲氨基)吡啶 as an Impurity". Anal. Chem., 2016, 1995, (10), 9723-9751.
  3. Chen X Y, Liu M, Zhao W Q. "Identification and Structural Characterization of a Novel Degradation Product of 4-(Dimethylamino)pyridine, polymer-bound 82942-26-5 DMAP on polystyrene N-Benzyl-4-(methylamino)pyridine, polymer-bound N-Methyl-N-(4-pyridyl)aminomethyl-polystyrene, cross-linked with divinylbenzene inverted exclamation markaDimethylaminopyridine inverted exclamation marka on polystyrene Using HRMS and NMR". Anal. Chim. Acta, 2020, 534, (7), 3876-3887.
  4. Fischer P, Wagner E. "Forced Degradation Studies to Evaluate 聚合物键合型 4-(二甲氨基)吡啶 Profile in Drug Substances According to ICH Guidelines". Chemosphere, 2010, 234, (7), 8300-8325.

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