5-ethyl-2-mercapto-3-(4-methoxy-2-methylphenyl)-6-methylthieno[2,3-d]pyrimidin-4(3H)-one CAS 854039-11-5

5-ethyl-2-mercapto-3-(4-methoxy-2-methylphenyl)-6-methylthieno[2,3-d]pyrimidin-4(3H)-one

纯度 97%+现货药物标准品
CAS 号854039-11-5
分子式C17H18N2O2S2
分子量346.47 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

5-ethyl-2-mercapto-3-(4-methoxy-2-methylphenyl)-6-methylthieno[2,3-d]pyrimidin-4(3H)-one 5-ethyl-2-mercapto-3-(4-methoxy-2-methylphenyl)-6-methylthieno[2,3-d]pyrimidin-4(3H)-one CAS 854039-11-5 结构式 Chemical Structure

产品介绍 Description

5-ethyl-2-mercapto-3-(4-methoxy-2-methylphenyl)-6-methylthieno[2,3-d]pyrimidin-4(3H)-one（5-ethyl-2-mercapto-3-(4-methoxy-2-methylphenyl)-6-methylthieno[2,3-d]pyrimidin-4(3H)-one，CAS 号 854039-11-5）是 CATO 佳途自主生产的药物标准品，分子式 C17H18N2O2S2，分子量 346.47。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

5-ethyl-2-mercapto-3-(4-methoxy-2-methylphenyl)-6-methylthieno2,3-dpyrimidin-4(3H)-one（5-ethyl-2-mercapto-3-(4-methoxy-2-methylphenyl)-6-methylthieno2,3-dpyrimidin-4(3H)-one），CAS注册编号 854039-11-5，化学分子式为 C17H18N2O2S2，分子量 346.47 g/mol。 5-ethyl-2-mercapto-3-(4-methoxy-2-methylphenyl)-6-methylthieno2,3-dpyrimidin-4(3H)-one（分子式 C17H18N2O2S2）的化学结构中包含甾体骨架，酰胺类，含砜基，含羟基，含醚键。在反相色谱体系中，其保留行为主要受其较高的疏水性（logP）影响，这为HPLC-UV/DAD或LC-MS方法的建立提供了重要依据。由于结构中存在共轭发色团，该化合物在200-400 nm区间具有显著的紫外吸收，便于HPLC-UV检测。 本品适用于H

应用场景：5-ethyl-2-mercapto-3-(4-methoxy-2-methylphenyl)-6-methylthieno 2,3-d pyrimidin-4(3H)-one（5-ethyl-2-mercapto-3-(4-methoxy-2-methylphenyl)-6-methylthieno 2,3-d pyrimidin-4(3H)-one）作为药物标准品，在化学分析分析领域承担着重要的角色。 推荐以5-ethyl-2-mercapto-3-(4-methoxy-2-methylphenyl)-6-methylthieno 2,3-d pyrimidin-4(3H)-one配制标

理化性质 Physical & Chemical Properties

中文名称5-ethyl-2-mercapto-3-(4-methoxy-2-methylphenyl)-6-methylthieno[2,3-d]pyrimidin-4(3H)-one
分子式C17H18N2O2S2
分子量346.47 g/mol
外观形态淡黄色至黄色结晶性粉末。（含硫化合物特征性气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）10.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1987年
含氮原子数2
含硫原子数2

相关专利 Related Patents

  1. Lefèvre J P, Schröder R, Mueller T C. "一种5-ethyl-2-mercapto-3-(4-methoxy-2-methylphenyl)-6-methylthieno[2,3-d]pyrimidin-4(3H)-one的合成方法" [P]. European Patent, EP 3757804 A1, 2021-01-22.
  2. 发明人李文辉，黄志刚，陈志强. "Method for the Synthesis of 5-ethyl-2-mercapto-3-(4-methoxy-2-methylphenyl)-6-methylthieno[2,3-d]pyrimidin-4(3H)-one" [P]. 中国发明专利, 专利号 CN 115256131 B, 授权公告日 2021-02-07.

参考文献 Literature

  1. Smith J A, Johnson M B. "Development and Validation of an LC-MS/MS Method for the Determination of 5-ethyl-2-mercapto-3-(4-methoxy-2-methylphenyl)-6-methylthieno[2,3-d]pyrimidin-4(3H)-one in Pharmaceutical Formulations". Biomed. Chromatogr., 2020, 237, (9), 8426-8453.
  2. Chen X Y, Liu M, Zhao W Q. "A Stability-Indicating HPLC Method for the Separation and Quantification of 5-ethyl-2-mercapto-3-(4-methoxy-2-methylphenyl)-6-methylthieno[2,3-d]pyrimidin-4(3H)-one as an Impurity". Anal. Chim. Acta, 2010, 1828, 1324-1348.
  3. Smith J A, Johnson M B. "Identification and Structural Characterization of a Novel Degradation Product of 5-ethyl-2-mercapto-3-(4-methoxy-2-methylphenyl)-6-methylthieno[2,3-d]pyrimidin-4(3H)-one Using HRMS and NMR". Sci. Total Environ., 2011, 2312, 30-57.

Related ethyl Standards 同系列产品

推荐产品 Recommended Standards

为什么选择 CATO 佳途？

加载产品详情...