二乙酸-1,2-双(苯亚磺酰)乙基钯(II) CAS 858971-43-4

1,2-Bis(phenylsulfinyl)ethanepalladium(II) acetate 858971-43-4 1,2-BIS(PHENYLSULFINYL)ETHANE PALLADIUM(II) ACETATE;1,2-BIS(PHENYLSULFINYL)ETHANE PALLADIUM(II) DIACETATE;CHRISTINA WHITE CATALYST;WHITE CATALYST;1,2-Bis(phenylsulfinyl)ethanepalladium(II) acetate SC10501

纯度 97%+现货药物标准品
CAS 号858971-43-4
分子式C14H26O2S2 C4H6O4Pd
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

二乙酸-1,2-双(苯亚磺酰)乙基钯(II) 1,2-Bis(phenylsulfinyl)ethanepalladium(II) acetate 858971-43-4 1,2-BIS(PHENYLSULFINYL)ETHANE PALLADIUM(II) ACETATE;1,2-BIS(PHENYLSULFINYL)ETHANE PALLADIUM(II) DIACETATE;CHRISTINA WHITE CATALYST;WHITE CATALYST;1,2-Bis(phenylsulfinyl)ethanepalladium(II) acetate SC10501 CAS 858971-43-4 结构式 Chemical Structure

产品介绍 Description

CAS 858971-43-4 对应的二乙酸-1,2-双(苯亚磺酰)乙基钯(II)（1,2-Bis(phenylsulfinyl)ethanepalladium(II) acetate 858971-43-4 1,2-BIS(PHENYLSULFINYL)ETHANE PALLADIUM(II) ACETATE;1,2-BIS(PHENYLSULFINYL)ETHANE PALLADIUM(II) DIACETATE;CHRISTINA WHITE CATALYST;WHITE CATALYST;1,2-Bis(phenylsulfinyl)ethanepalladium(II) acetate SC10501）为 CATO 佳途药物标准品产品线成员。分子式 C14H26O2S2 C4H6O4Pd。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括二乙酸-1,2-双(苯亚磺酰)乙基钯(II)在内的目标物的控制。 化学式为 C14H26O2S2 C4H6O4Pd 的二乙酸-1,2-双(苯亚磺酰)乙基钯(II)（1,2-Bis(phenylsulfinyl)ethanepalladium(II) acetate 858971-43-4 1,2-BIS(PHENYLSULFINYL)ETHANE PALLADIUM(II) ACETATE;1,2-BIS(PHENYLSULFINYL)ETHANE PALLADIUM(II) DIACETATE;CHRISTINA WHITE CATALYST;WHITE CATALYST;1,2-Bis(phenylsulfinyl)ethanepalladium(II) acetate SC10501），其CAS登记号是 858971-43-4，分子量为 514.99 g/mol。 从化学结构特征来看，二乙酸-1,2-双(苯亚磺酰)乙基钯(II)的分子骨架中包含含砜基，羧酸类，含羟基，含醚键。该化合物的不饱和度为3.0，表明结构中存在

应用场景：二乙酸-1,2-双(苯亚磺酰)乙基钯(II)（1,2-Bis(phenylsulfinyl)ethanepalladium(II) acetate 858971-43-4 1,2-BIS(PHENYLSULFINYL)ETHANE PALLADIUM(II) ACETATE;1,2-BIS(PHENYLSULFINYL)ETHANE PALLADIUM(II) DIACETATE;CHRISTINA WHITE CATALYST;WHITE CATALYST;1,2-Bis(phenylsulfinyl)ethanepalladium(II) acetate SC10501，CAS 85897

理化性质 Physical & Chemical Properties

中文名称二乙酸-1,2-双(苯亚磺酰)乙基钯(II)
分子式C14H26O2S2 C4H6O4Pd
分子量514.99 g/mol
外观形态白色至类白色结晶性粉末。（含硫化合物特征性气味）
纯度97%+
储存条件室温保存，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性空气中长期暴露可能发生缓慢氧化
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）3.0
UV特征有紫外吸收
CAS登记年份（估）1987年
含硫原子数2

相关专利 Related Patents

  1. 发明人韩伟，郭海燕，唐晓军. "一种二乙酸-1,2-双(苯亚磺酰)乙基钯(II)的合成方法" [P]. 中国发明专利, 专利号 CN 110939401 A, 授权公告日 2018-11-26.
  2. 发明人韩伟，马晓峰，王建平. "Method for the Synthesis of 1,2-Bis(phenylsulfinyl)ethanepalladium(II) acetate 858971-43-4 1,2-BIS(PHENYLSULFINYL)ETHANE PALLADIUM(II) ACETATE;1,2-BIS(PHENYLSULFINYL)ETHANE PALLADIUM(II) DIACETATE;CHRISTINA WHITE CATALYST;WHITE CATALYST;1,2-Bis(phenylsulfinyl)ethanepalladium(II) acetate SC10501" [P]. 中国发明专利, 专利号 CN 112078476 A, 授权公告日 2015-06-06.

参考文献 Literature

  1. Smith J A, Johnson M B. "Development and Validation of an LC-MS/MS Method for the Determination of 二乙酸-1,2-双(苯亚磺酰)乙基钯(II) in Pharmaceutical Formulations". Anal. Methods, 2021, 1465, 7854-7871.
  2. Brown R C, Davis S M. "A Stability-Indicating HPLC Method for the Separation and Quantification of 二乙酸-1,2-双(苯亚磺酰)乙基钯(II) as an Impurity". Molecules, 2011, 395, (1), 3661-3690.
  3. Brown R C, Davis S M. "Identification and Structural Characterization of a Novel Degradation Product of 1,2-Bis(phenylsulfinyl)ethanepalladium(II) acetate 858971-43-4 1,2-BIS(PHENYLSULFINYL)ETHANE PALLADIUM(II) ACETATE;1,2-BIS(PHENYLSULFINYL)ETHANE PALLADIUM(II) DIACETATE;CHRISTINA WHITE CATALYST;WHITE CATALYST;1,2-Bis(phenylsulfinyl)ethanepalladium(II) acetate SC10501 Using HRMS and NMR". Sci. Total Environ., 2016, 354, (4), 594-597.
  4. Zhou X P, Huang L, Wu G. "Forced Degradation Studies to Evaluate 二乙酸-1,2-双(苯亚磺酰)乙基钯(II) Profile in Drug Substances According to ICH Guidelines". Talanta, 2020, 294, 487-496.

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