4,4,4-三氟-1-(2-萘基)-1,3-丁二酮 CAS 893-33-4

893-33-4 AR-1I2308 chromium(3+) sodium[(3-chloro-5-{[1-(2,6-dimethyl-3-sulfamoylphenyl)-3-methyl-5-oxo-1,5-dihydro-4h-pyrazol-4-ylidene]hydrazinylidene}-6-oxocyclohexa-1,3-dien-1-yl)imino]dioxidanide 4-[(3-chloro-5-nitro-6-oxocyclohexa-2,4-dien-1-ylidene)diazanidyl]-1-(2,6-dimethyl-3-sulfamoylphenyl)-3-methyl-1h-pyrazol-5-olate(1:1:1:1)

纯度 97%+现货药物标准品

CAS 号	893-33-4
分子式	C14H19F3O2
分子量	276.29 g/mol
分类	药物标准品 / 原料药标准品
库存状态	现货

化学结构式 Structure

4,4,4-三氟-1-(2-萘基)-1,3-丁二酮 893-33-4
AR-1I2308
chromium(3+) sodium[(3-chloro-5-{[1-(2,6-dimethyl-3-sulfamoylphenyl)-3-methyl-5-oxo-1,5-dihydro-4h-pyrazol-4-ylidene]hydrazinylidene}-6-oxocyclohexa-1,3-dien-1-yl)imino]dioxidanide 4-[(3-chloro-5-nitro-6-oxocyclohexa-2,4-dien-1-ylidene)diazanidyl]-1-(2,6-dimethyl-3-sulfamoylphenyl)-3-methyl-1h-pyrazol-5-olate(1:1:1:1) CAS 893-33-4 结构式 Chemical Structure

产品介绍 Description

4,4,4-三氟-1-(2-萘基)-1,3-丁二酮（英文名 893-33-4 AR-1I2308 chromium(3+) sodium[(3-chloro-5-{[1-(2,6-dimethyl-3-sulfamoylphenyl)-3-methyl-5-oxo-1,5-dihydro-4h-pyrazol-4-ylidene]hydrazinylidene}-6-oxocyclohexa-1,3-dien-1-yl)imino]dioxidanide 4-[(3-chloro-5-nitro-6-oxocyclohexa-2,4-dien-1-ylidene)diazanidyl]-1-(2,6-dimethyl-3-sulfamoylphenyl)-3-methyl-1h-pyrazol-5-olate(1:1:1:1)，CAS 893-33-4）属于药物标准品。分子式 C14H19F3O2，分子量 276.29。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

4,4,4-三氟-1-(2-萘基)-1,3-丁二酮（C14H19F3O2）含有羧酸类，含羟基，含醚键，含氟取代。卤素取代增加了化合物的密度和沸点，较高的碳氢比使其脂溶性较好，羧基赋予其一定的酸性特征，这些物理化学性质直接决定了其标准溶液的最佳配制方案和储存策略。较高的碳氢原子比赋予该化合物良好的脂溶性，可使用正己烷或乙酸乙酯等非极性溶剂进行液-液萃取前处理。 CAS编号 893-33-4 对应的化合物4,4,4-三氟-1-(2-萘基)-1,3-丁二酮（英文标识 893-33-4 AR-1I2308 chromium(3+) sodium(3-chloro-5-{1-(2,6-dimethyl-3-sulfamoylphenyl)-3-methyl-5-oxo-1,5-dihydro-4h-pyrazol-4-ylidenehydrazinylidene}-6-oxocyclohexa-1,3-dien-1-yl)iminodioxidanide 4-(3-chloro-5-nitro-6-oxocyclohexa-2,4-dien-1-ylidene)diazanidyl

应用场景：4,4,4-三氟-1-(2-萘基)-1,3-丁二酮（893-33-4 AR-1I2308 chromium(3+) sodium (3-chloro-5-{ 1-(2,6-dimethyl-3-sulfamoylphenyl)-3-methyl-5-oxo-1,5-dihydro-4h-pyrazol-4-ylidene hydrazinylidene}-6-oxocyclohexa-1,3-dien-1-yl)imino dioxidanide 4- (3-chloro-5-nitro-6-oxocyclohexa-2,4-dien-1-ylidene)diazanidyl -1-(2,6-

理化性质 Physical & Chemical Properties

中文名称	4,4,4-三氟-1-(2-萘基)-1,3-丁二酮
分子式	C14H19F3O2
分子量	276.29 g/mol
外观形态	类白色至淡黄色结晶性粉末。（具有轻微卤代物特征气味，挥发性较低）
纯度	97%+
储存条件	室温保存，密闭保存防止挥发
溶解性参考	可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO
稳定性	空气中长期暴露可能发生缓慢氧化；含酯键，遇强碱易水解
化合物类型	药物标准品
子类	原料药标准品
不饱和度（DBE）	4.0
UV特征	有紫外吸收
结构特征	含芳环
CAS登记年份（估）	1957年
卤素含量	F取代

参考文献 Literature

Kowalski T, Nowak Z. "Development and Validation of an LC-MS/MS Method for the Determination of 4,4,4-三氟-1-(2-萘基)-1,3-丁二酮 in Pharmaceutical Formulations". Sci. Total Environ., 2022, 1833, 8784-8806.
Kowalski T, Nowak Z. "A Stability-Indicating HPLC Method for the Separation and Quantification of 4,4,4-三氟-1-(2-萘基)-1,3-丁二酮 as an Impurity". Rapid Commun. Mass Spectrom., 2022, 734, 1235-1260.
Chen X Y, Liu M, Zhao W Q. "Identification and Structural Characterization of a Novel Degradation Product of 893-33-4 AR-1I2308 chromium(3+) sodium[(3-chloro-5-{[1-(2,6-dimethyl-3-sulfamoylphenyl)-3-methyl-5-oxo-1,5-dihydro-4h-pyrazol-4-ylidene]hydrazinylidene}-6-oxocyclohexa-1,3-dien-1-yl)imino]dioxidanide 4-[(3-chloro-5-nitro-6-oxocyclohexa-2,4-dien-1-ylidene)diazanidyl]-1-(2,6-dimethyl-3-sulfamoylphenyl)-3-methyl-1h-pyrazol-5-olate(1:1:1:1) Using HRMS and NMR". Phytochemistry, 2019, 2041, 453-466.
Brown R C, Davis S M. "Forced Degradation Studies to Evaluate 4,4,4-三氟-1-(2-萘基)-1,3-丁二酮 Profile in Drug Substances According to ICH Guidelines". Biomed. Chromatogr., 2020, 857, (7), 3467-3487.

为什么选择 CATO 佳途？

ISO 17034 / CNAS / ANAB 三重认证标准物质生产商
130,000+ 品种现货库存，支持 COA 定制
专业技术支持：+86 13829788188 / jacky.chen@cato-chem.com
全球 10,000+ 客户信赖之选