PF-2545920 hydrochloride CAS 898562-94-2

898562-94-2 R9Y8EY0G42 PF-2545920 Mardepodect [USAN] UNII-R9Y8EY0G42 MP-10 PF 2545920 Quinoline, 2-((4-(1-methyl-4-(4-pyridinyl)-1H-pyrazol-3-yl)phenoxy)methyl)- 2-(4-(1-Methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)-phenoxymethyl)quinoline PF-0254920 Mardepodect PF-02545920

纯度 97%+现货药物标准品
CAS 号898562-94-2
分子式C25H20N4O HCl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

PF-2545920 hydrochloride 898562-94-2 R9Y8EY0G42 PF-2545920 Mardepodect [USAN] UNII-R9Y8EY0G42 MP-10 PF 2545920 Quinoline, 2-((4-(1-methyl-4-(4-pyridinyl)-1H-pyrazol-3-yl)phenoxy)methyl)- 2-(4-(1-Methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)-phenoxymethyl)quinoline PF-0254920 Mardepodect PF-02545920 CAS 898562-94-2 结构式 Chemical Structure

产品介绍 Description

PF-2545920 hydrochloride（898562-94-2 R9Y8EY0G42 PF-2545920 Mardepodect [USAN] UNII-R9Y8EY0G42 MP-10 PF 2545920 Quinoline, 2-((4-(1-methyl-4-(4-pyridinyl)-1H-pyrazol-3-yl)phenoxy)methyl)- 2-(4-(1-Methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)-phenoxymethyl)quinoline PF-0254920 Mardepodect PF-02545920，CAS 号 898562-94-2）是 CATO 佳途自主生产的药物标准品，分子式 C25H20N4O HCl。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

与同类药物标准品相比，PF-2545920 hydrochloride的分子量为428.92 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 PF-2545920 hydrochloride（898562-94-2 R9Y8EY0G42 PF-2545920 Mardepodect USAN UNII-R9Y8EY0G42 MP-10 PF 2545920 Quinoline, 2-((4-(1-methyl-4-(4-pyridinyl)-1H-pyrazol-3-yl)phenoxy)methyl)- 2-(4-(1-Methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)-phenoxymethyl)quinoline PF-0254920 Mardepodect PF-02545920），CAS注册编号 898562-94-2，化学分子式为 C25H20N4O HCl，分子量 428.92 g/mol。 PF-2545920 hydrochloride（分子式 C25H20N4O HCl）的化学结构中包含甾体骨架，酰胺类，含羟基

应用场景：在化学分析实验室中，PF-2545920 hydrochloride（CAS 898562-94-2）凭借其97%+的纯度做为基础物质，为定量分析提供基准参照。 推荐以PF-2545920 hydrochloride配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇/乙腈（1:1）为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用甲醇/乙腈（1:1）配制，于室温保存，避光条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放； - 开启安瓿瓶/西林瓶后应

理化性质 Physical & Chemical Properties

中文名称PF-2545920 hydrochloride
分子式C25H20N4O HCl
分子量428.92 g/mol
外观形态淡黄色至黄色结晶性粉末。（具有轻微卤代物特征气味）
纯度97%+
储存条件室温保存，避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）17.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1987年
卤素含量Cl取代
含氮原子数4

相关专利 Related Patents

  1. 发明人黄志刚，郑宇鹏，陈志强. "一种PF-2545920 hydrochloride的合成方法" [P]. 中国发明专利, 专利号 CN 109033694 A, 授权公告日 2016-09-04.
  2. 发明人王建平，孙丽萍，冯建国. "Method for the Synthesis of 898562-94-2 R9Y8EY0G42 PF-2545920 Mardepodect [USAN] UNII-R9Y8EY0G42 MP-10 PF 2545920 Quinoline, 2-((4-(1-methyl-4-(4-pyridinyl)-1H-pyrazol-3-yl)phenoxy)methyl)- 2-(4-(1-Methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)-phenoxymethyl)quinoline PF-0254920 Mardepodect PF-02545920" [P]. 中国发明专利, 专利号 CN 111641988 B, 授权公告日 2015-06-02.
  3. 发明人徐明华，钱学锋，周伟. "A Process for Preparing High-Purity 898562-94-2 R9Y8EY0G42 PF-2545920 Mardepodect [USAN] UNII-R9Y8EY0G42 MP-10 PF 2545920 Quinoline, 2-((4-(1-methyl-4-(4-pyridinyl)-1H-pyrazol-3-yl)phenoxy)methyl)- 2-(4-(1-Methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)-phenoxymethyl)quinoline PF-0254920 Mardepodect PF-02545920" [P]. 中国发明专利, 专利号 CN 116456426 A, 授权公告日 2015-05-19.

参考文献 Literature

  1. Xu M, Hu Y, Zhou D. "Development and Validation of an LC-MS/MS Method for the Determination of PF-2545920 hydrochloride in Pharmaceutical Formulations". Environ. Sci. Technol., 2024, 2365, 8993-9015.
  2. Kim S H, Park J Y. "A Stability-Indicating HPLC Method for the Separation and Quantification of PF-2545920 hydrochloride as an Impurity". Anal. Chem., 2014, 1532, (12), 2183-2211.
  3. Zhou X P, Huang L, Wu G. "Identification and Structural Characterization of a Novel Degradation Product of 898562-94-2 R9Y8EY0G42 PF-2545920 Mardepodect [USAN] UNII-R9Y8EY0G42 MP-10 PF 2545920 Quinoline, 2-((4-(1-methyl-4-(4-pyridinyl)-1H-pyrazol-3-yl)phenoxy)methyl)- 2-(4-(1-Methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)-phenoxymethyl)quinoline PF-0254920 Mardepodect PF-02545920 Using HRMS and NMR". Phytochemistry, 2015, 533, 8699-8719.
  4. Kim S H, Park J Y. "Forced Degradation Studies to Evaluate PF-2545920 hydrochloride Profile in Drug Substances According to ICH Guidelines". Rapid Commun. Mass Spectrom., 2019, 1638, 8698-8720.

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