DMT-dG（ib）亚磷酰胺 CAS 93183-15-4

5'-O-(4,4-Dimethoxytrityl)-N-isobutyryl-2'-deoxyguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite 5'-O-DMT-2'-dG(N-iBu)-3'-CEDPA 93183-15-4 deoxyguanosine-ce phosphoramidite*for cyclone dmt-dg(dmf) amidite 2g 89 12 pack dmt-dg(dmf) amidite 5g, single dmt-dg(ib) amidite 2g ab 12 pack dmt-dg(ib) amidite 5g single dna g phosphoramidite

纯度 97%+现货药物标准品
CAS 号93183-15-4
分子式C44H76N7O8P
分子量862.09 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

DMT-dG（ib）亚磷酰胺 5'-O-(4,4-Dimethoxytrityl)-N-isobutyryl-2'-deoxyguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite 5'-O-DMT-2'-dG(N-iBu)-3'-CEDPA 93183-15-4 deoxyguanosine-ce phosphoramidite*for cyclone dmt-dg(dmf) amidite 2g 89 12 pack dmt-dg(dmf) amidite 5g, single dmt-dg(ib) amidite 2g ab 12 pack dmt-dg(ib) amidite 5g single dna g phosphoramidite CAS 93183-15-4 结构式 Chemical Structure

产品介绍 Description

本产品为药物标准品DMT-dG（ib）亚磷酰胺（5'-O-(4,4-Dimethoxytrityl)-N-isobutyryl-2'-deoxyguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite 5'-O-DMT-2'-dG(N-iBu)-3'-CEDPA 93183-15-4 deoxyguanosine-ce phosphoramidite*for cyclone dmt-dg(dmf) amidite 2g 89 12 pack dmt-dg(dmf) amidite 5g, single dmt-dg(ib) amidite 2g ab 12 pack dmt-dg(ib) amidite 5g single dna g phosphoramidite，CAS 93183-15-4），分子式 C44H76N7O8P，分子量 862.09。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。

化学式为 C44H76N7O8P 的DMT-dG（ib）亚磷酰胺（5'-O-(4,4-Dimethoxytrityl)-N-isobutyryl-2'-deoxyguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite 5'-O-DMT-2'-dG(N-iBu)-3'-CEDPA 93183-15-4 deoxyguanosine-ce phosphoramiditefor cyclone dmt-dg(dmf) amidite 2g 89 12 pack dmt-dg(dmf) amidite 5g, single dmt-dg(ib) amidite 2g ab 12 pack dmt-dg(ib) amidite 5g single dna g phosphoramidite），其CAS登记号是 93183-15-4，分子量为 862.09 g/mol。 DMT-dG（ib）亚磷酰胺（分子式 C44H76N7O8P）的化学结构中包含含氮杂环结构，酰胺类，含磷酸酯基，含羟基，含醚键。在反相色谱体系中，其保留行为主要

应用场景：针对化学分析用途，DMT-dG（ib）亚磷酰胺（5'-O-(4,4-Dimethoxytrityl)-N-isobutyryl-2'-deoxyguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite 5'-O-DMT-2'-dG(N-iBu)-3'-CEDPA 93183-15-4 deoxyguanosine-ce phosphoramidite for cyclone dmt-dg(dmf) amidite 2g 89 12 pack dmt-dg(dmf) amidite 5g, single dmt-dg(ib) amidi

理化性质 Physical & Chemical Properties

中文名称DMT-dG（ib）亚磷酰胺
分子式C44H76N7O8P
分子量862.09 g/mol
外观形态淡黄色至黄色无定形粉末
纯度97%+
储存条件阴凉处（≤25°C）保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）10.5
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1983年
含氮原子数7

相关专利 Related Patents

  1. 发明人张德明，林芳，韩伟. "一种DMT-dG（ib）亚磷酰胺的合成方法" [P]. 中国发明专利, 专利号 CN 111594027 B, 授权公告日 2019-05-19.
  2. 发明人郑宇鹏，陈志强，冯建国. "Method for the Synthesis of 5'-O-(4,4-Dimethoxytrityl)-N-isobutyryl-2'-deoxyguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite 5'-O-DMT-2'-dG(N-iBu)-3'-CEDPA 93183-15-4 deoxyguanosine-ce phosphoramidite*for cyclone dmt-dg(dmf) amidite 2g 89 12 pack dmt-dg(dmf) amidite 5g, single dmt-dg(ib) amidite 2g ab 12 pack dmt-dg(ib) amidite 5g single dna g phosphoramidite" [P]. 中国发明专利, 专利号 CN 115215342 B, 授权公告日 2016-07-06.
  3. 发明人郭海燕，钱学锋，罗永刚. "A Process for Preparing High-Purity 5'-O-(4,4-Dimethoxytrityl)-N-isobutyryl-2'-deoxyguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite 5'-O-DMT-2'-dG(N-iBu)-3'-CEDPA 93183-15-4 deoxyguanosine-ce phosphoramidite*for cyclone dmt-dg(dmf) amidite 2g 89 12 pack dmt-dg(dmf) amidite 5g, single dmt-dg(ib) amidite 2g ab 12 pack dmt-dg(ib) amidite 5g single dna g phosphoramidite" [P]. 中国发明专利, 专利号 CN 112708803 A, 授权公告日 2018-05-20.

参考文献 Literature

  1. Smith J A, Johnson M B. "Development and Validation of an LC-MS/MS Method for the Determination of DMT-dG（ib）亚磷酰胺 in Pharmaceutical Formulations". Phytochemistry, 2012, 880, 6963-6990.
  2. Kumar A, Sharma P, Patel R S. "A Stability-Indicating HPLC Method for the Separation and Quantification of DMT-dG（ib）亚磷酰胺 as an Impurity". J. Pharm. Biomed. Anal., 2025, 1280, (10), 5187-5217.

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