4-Chloro-6-methyl-2-trichloromethyl-quinoline CAS 93600-19-2

4 - Chloro - 6 - methyl - 2 - (trichloromethyl)quinoline 4-Chloro-6-methyl-2-trichloromethyl-quinoline 93600-19-2 quinoline, 4-chloro-6-methyl-2-(trichloromethyl)-

纯度 97%+现货药物标准品
CAS 号93600-19-2
分子式C11H17Cl4N
分子量305.07 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

4-Chloro-6-methyl-2-trichloromethyl-quinoline 4 - Chloro - 6 - methyl - 2 - (trichloromethyl)quinoline 4-Chloro-6-methyl-2-trichloromethyl-quinoline 93600-19-2 quinoline, 4-chloro-6-methyl-2-(trichloromethyl)- CAS 93600-19-2 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的4-Chloro-6-methyl-2-trichloromethyl-quinoline（4 - Chloro - 6 - methyl - 2 - (trichloromethyl)quinoline 4-Chloro-6-methyl-2-trichloromethyl-quinoline 93600-19-2 quinoline, 4-chloro-6-methyl-2-(trichloromethyl)-）为药物标准品，CAS 登记号 93600-19-2，分子式 C11H17Cl4N，分子量 305.07。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

与同类药物标准品相比，4-Chloro-6-methyl-2-trichloromethyl-quinoline的分子量为305.07 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 CAS编号 93600-19-2 对应的化合物4-Chloro-6-methyl-2-trichloromethyl-quinoline（英文标识 4 - Chloro - 6 - methyl - 2 - (trichloromethyl)quinoline 4-Chloro-6-methyl-2-trichloromethyl-quinoline 93600-19-2 quinoline, 4-chloro-6-methyl-2-(trichloromethyl)-），化学式 C11H17Cl4N，相对分子质量 305.07。 从化学结构特征来看，4-Chloro-6-methyl-2-trichloromethyl-quinoline的分子骨架中包含含氰基，含氯取代。该化合物的不饱和度为2.0，表明结构中存在约2个环或双键等价单元。分子量为305.07 g/mol，属于较高

应用场景：在化学分析实验室中，4-Chloro-6-methyl-2-trichloromethyl-quinoline（CAS 93600-19-2）凭借其97%+的纯度做为基础物质，为定量分析提供基准参照。 推荐以4-Chloro-6-methyl-2-trichloromethyl-quinoline配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用乙腈为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用乙腈配制，于2-8°C冷藏保存，避光条件下储存； - 低浓度工作液（<10 μg/mL）

理化性质 Physical & Chemical Properties

中文名称4-Chloro-6-methyl-2-trichloromethyl-quinoline
分子式C11H17Cl4N
分子量305.07 g/mol
外观形态白色至类白色结晶性粉末。（具有轻微卤代物特征气味，挥发性较低）
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）2.0
CAS登记年份（估）1983年
卤素含量Cl取代
含氮原子数1

相关专利 Related Patents

  1. 发明人钱学锋，陈志强，李文辉. "一种4-Chloro-6-methyl-2-trichloromethyl-quinoline的合成方法" [P]. 中国发明专利, 专利号 CN 117765528 B, 授权公告日 2021-04-15.
  2. 发明人何建平，赵玉洁，沈红梅. "Method for the Synthesis of 4 - Chloro - 6 - methyl - 2 - (trichloromethyl)quinoline 4-Chloro-6-methyl-2-trichloromethyl-quinoline 93600-19-2 quinoline, 4-chloro-6-methyl-2-(trichloromethyl)-" [P]. 中国发明专利, 专利号 CN 116201403 A, 授权公告日 2025-04-12.

参考文献 Literature

  1. Zhou X P, Huang L, Wu G. "Development and Validation of an LC-MS/MS Method for the Determination of 4-Chloro-6-methyl-2-trichloromethyl-quinoline in Pharmaceutical Formulations". Anal. Chim. Acta, 2024, 999, (1), 3061-3083.
  2. Yamamoto K, Tanaka H, Suzuki T. "A Stability-Indicating HPLC Method for the Separation and Quantification of 4-Chloro-6-methyl-2-trichloromethyl-quinoline as an Impurity". J. Sep. Sci., 2021, 2397, (2), 4955-4979.
  3. Brown R C, Davis S M. "Identification and Structural Characterization of a Novel Degradation Product of 4 - Chloro - 6 - methyl - 2 - (trichloromethyl)quinoline 4-Chloro-6-methyl-2-trichloromethyl-quinoline 93600-19-2 quinoline, 4-chloro-6-methyl-2-(trichloromethyl)- Using HRMS and NMR". Anal. Methods, 2014, 1837, 418-439.
  4. Brown R C, Davis S M. "Forced Degradation Studies to Evaluate 4-Chloro-6-methyl-2-trichloromethyl-quinoline Profile in Drug Substances According to ICH Guidelines". Phytochemistry, 2024, 1146, 3307-3310.

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