CAS 94168-98-6

94168-98-6 1PUG6262HX Rifametane [USAN:INN] Rifametane Rifamycin, 3-(((1-(diethylamino)ethylidene)hydrazono)methyl)- (2S,12Z,14E,16S,17S,18R,19R,20R,21S,22S,23S,24E)-1,2-Dihydro-5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-2,7-(epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-8-carboxyaldehyde, 8-azine with N,N-diethylacetamide, 21-acetate Rifametano [INN-Spanish] Rifametanum [INN-Latin] SPA S565 Rifametano Rifametanum UNII-1PUG6262HX SPA-S-565 Spa-S 565

纯度 97%+现货药物标准品
CAS 号94168-98-6
分子式C44H60N4O12
分子量836.97 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

 94168-98-6
1PUG6262HX
Rifametane [USAN:INN]
Rifametane
Rifamycin, 3-(((1-(diethylamino)ethylidene)hydrazono)methyl)-
(2S,12Z,14E,16S,17S,18R,19R,20R,21S,22S,23S,24E)-1,2-Dihydro-5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-2,7-(epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-8-carboxyaldehyde, 8-azine with N,N-diethylacetamide, 21-acetate
Rifametano [INN-Spanish]
Rifametanum [INN-Latin]
SPA S565
Rifametano
Rifametanum
UNII-1PUG6262HX
SPA-S-565
Spa-S 565 CAS 94168-98-6 结构式 Chemical Structure

产品介绍 Description

(94168-98-6 1PUG6262HX Rifametane [USAN:INN] Rifametane Rifamycin, 3-(((1-(diethylamino)ethylidene)hydrazono)methyl)- (2S,12Z,14E,16S,17S,18R,19R,20R,21S,22S,23S,24E)-1,2-Dihydro-5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-2,7-(epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-8-carboxyaldehyde, 8-azine with N,N-diethylacetamide, 21-acetate Rifametano [INN-Spanish] Rifametanum [INN-Latin] SPA S565 Rifametano Rifametanum UNII-1PUG6262HX SPA-S-565 Spa-S 565)是药物分析与质量控制领域常用的药物标准品,CAS 号 94168-98-6。分子式 C44H60N4O12,分子量 836.97。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录,可一站式满足配套采购需求。

与同类药物标准品相比,的分子量为836.97 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 (94168-98-6 1PUG6262HX Rifametane USAN:INN Rifametane Rifamycin, 3-(((1-(diethylamino)ethylidene)hydrazono)methyl)- (2S,12Z,14E,16S,17S,18R,19R,20R,21S,22S,23S,24E)-1,2-Dihydro-5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-2,7-(epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-8-carboxyaldehyde, 8-azine with N,N-diethylacetamide, 21-acetate Rifametano INN-Spanish Rifametanum INN-Latin SPA S565

应用场景:(94168-98-6 1PUG6262HX Rifametane USAN:INN Rifametane Rifamycin, 3-(((1-(diethylamino)ethylidene)hydrazono)methyl)- (2S,12Z,14E,16S,17S,18R,19R,20R,21S,22S,23S,24E)-1,2-Dihydro-5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-2,7-(epoxypentadeca(1,11,13)trienimino)na

理化性质 Physical & Chemical Properties

中文名称
分子式C44H60N4O12
分子量836.97 g/mol
外观形态淡黄色至黄色无定形粉末
纯度97%+
储存条件阴凉处(≤25°C)保存,避光,密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化;对光敏感,应避免强光直射;具有吸湿性,开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度(DBE)17.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份(估)1983年
含氮原子数4

相关专利 Related Patents

  1. 发明人陈志强,韩伟,赵玉洁. "一种的合成方法" [P]. 中国发明专利, 专利号 CN 115336774 A, 授权公告日 2021-09-07.
  2. 发明人周伟,钱学锋,杨光. "Method for the Synthesis of 94168-98-6 1PUG6262HX Rifametane [USAN:INN] Rifametane Rifamycin, 3-(((1-(diethylamino)ethylidene)hydrazono)methyl)- (2S,12Z,14E,16S,17S,18R,19R,20R,21S,22S,23S,24E)-1,2-Dihydro-5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-2,7-(epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-8-carboxyaldehyde, 8-azine with N,N-diethylacetamide, 21-acetate Rifametano [INN-Spanish] Rifametanum [INN-Latin] SPA S565 Rifametano Rifametanum UNII-1PUG6262HX SPA-S-565 Spa-S 565" [P]. 中国发明专利, 专利号 CN 113954396 A, 授权公告日 2024-10-01.
  3. Kowalski A, Martínez F, Schröder R. "A Process for Preparing High-Purity 94168-98-6 1PUG6262HX Rifametane [USAN:INN] Rifametane Rifamycin, 3-(((1-(diethylamino)ethylidene)hydrazono)methyl)- (2S,12Z,14E,16S,17S,18R,19R,20R,21S,22S,23S,24E)-1,2-Dihydro-5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-2,7-(epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-8-carboxyaldehyde, 8-azine with N,N-diethylacetamide, 21-acetate Rifametano [INN-Spanish] Rifametanum [INN-Latin] SPA S565 Rifametano Rifametanum UNII-1PUG6262HX SPA-S-565 Spa-S 565" [P]. European Patent, EP 3846942 A1, 2015-11-20.

参考文献 Literature

  1. Wang L, Li J, Zhang H. "Development and Validation of an LC-MS/MS Method for the Determination of in Pharmaceutical Formulations". Rapid Commun. Mass Spectrom., 2025, 1272, (7), 2394-2411.
  2. Yamamoto K, Tanaka H, Suzuki T. "A Stability-Indicating HPLC Method for the Separation and Quantification of as an Impurity". J. Sep. Sci., 2012, 1667, (3), 3736-3746.
  3. Martinez C, Lopez D R. "Identification and Structural Characterization of a Novel Degradation Product of 94168-98-6 1PUG6262HX Rifametane [USAN:INN] Rifametane Rifamycin, 3-(((1-(diethylamino)ethylidene)hydrazono)methyl)- (2S,12Z,14E,16S,17S,18R,19R,20R,21S,22S,23S,24E)-1,2-Dihydro-5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-2,7-(epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-8-carboxyaldehyde, 8-azine with N,N-diethylacetamide, 21-acetate Rifametano [INN-Spanish] Rifametanum [INN-Latin] SPA S565 Rifametano Rifametanum UNII-1PUG6262HX SPA-S-565 Spa-S 565 Using HRMS and NMR". Anal. Chem., 2023, 1929, 1956-1975.

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