(<I>R</I>)-(+)-α,α-二苯基-2-吡咯烷甲醇三甲基硅基醚 CAS 943757-71-9

(2R)-2-[Diphenyl[(trimethylsilyl)oxy]methyl]pyrrolidine (R)-(+)-|A,|A-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether (R)-(+)-|A,|A-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether solution (R)-2-[Diphenyl(trimethylsilanyloxy)methyl]pyrrolidine (R)-2-[Diphenyl(trimethylsilanyloxy)methyl]pyrrolidine solution (R)-|A,|A-Diphenylprolinol trimethylsilyl ether (R)-|A,|A-Diphenylprolinol trimethylsilyl ether solution 943757-71-9

纯度 97%+现货药物标准品
CAS 号943757-71-9
分子式C20H39NOSi
分子量337.62 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

(<I>R</I>)-(+)-α,α-二苯基-2-吡咯烷甲醇三甲基硅基醚 (2R)-2-[Diphenyl[(trimethylsilyl)oxy]methyl]pyrrolidine
(R)-(+)-|A,|A-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether
(R)-(+)-|A,|A-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether solution
(R)-2-[Diphenyl(trimethylsilanyloxy)methyl]pyrrolidine
(R)-2-[Diphenyl(trimethylsilanyloxy)methyl]pyrrolidine solution
(R)-|A,|A-Diphenylprolinol trimethylsilyl ether
(R)-|A,|A-Diphenylprolinol trimethylsilyl ether solution
943757-71-9 CAS 943757-71-9 结构式 Chemical Structure

产品介绍 Description

(<I>R</I>)-(+)-α,α-二苯基-2-吡咯烷甲醇三甲基硅基醚((2R)-2-[Diphenyl[(trimethylsilyl)oxy]methyl]pyrrolidine (R)-(+)-|A,|A-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether (R)-(+)-|A,|A-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether solution (R)-2-[Diphenyl(trimethylsilanyloxy)methyl]pyrrolidine (R)-2-[Diphenyl(trimethylsilanyloxy)methyl]pyrrolidine solution (R)-|A,|A-Diphenylprolinol trimethylsilyl ether (R)-|A,|A-Diphenylprolinol trimethylsilyl ether solution 943757-71-9)是药物分析与质量控制领域常用的药物标准品,CAS 号 943757-71-9。分子式 C20H39NOSi,分子量 337.62。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录,可一站式满足配套采购需求。

化学式为 C20H39NOSi 的(<I>R</I>)-(+)-α,α-二苯基-2-吡咯烷甲醇三甲基硅基醚((2R)-2-Diphenyl(trimethylsilyl)oxymethylpyrrolidine (R)-(+)-|A,|A-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether (R)-(+)-|A,|A-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether solution (R)-2-Diphenyl(trimethylsilanyloxy)methylpyrrolidine (R)-2-Diphenyl(trimethylsilanyloxy)methylpyrrolidine solution (R)-|A,|A-Diphenylprolinol trimethylsilyl ether (R)-|A,|A-Diphenylprolinol trimethylsilyl ether solution 943757-71-9),其CAS登记号是 943

应用场景:(<I>R</I>)-(+)-α,α-二苯基-2-吡咯烷甲醇三甲基硅基醚((2R)-2- Diphenyl (trimethylsilyl)oxy methyl pyrrolidine (R)-(+)-|A,|A-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether (R)-(+)-|A,|A-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether solution (R)-2- Diphenyl(trimethylsilanyloxy)methyl pyrrolidine (R)-2- Diph

理化性质 Physical & Chemical Properties

中文名称(<I>R</I>)-(+)-α,α-二苯基-2-吡咯烷甲醇三甲基硅基醚
分子式C20H39NOSi
分子量337.62 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存,避光
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO
稳定性对光敏感,应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度(DBE)2.0
CAS登记年份(估)1987年
含氮原子数1

相关专利 Related Patents

  1. Kowalski A, Lefèvre J P, Sørensen M. "一种(<I>R</I>)-(+)-α,α-二苯基-2-吡咯烷甲醇三甲基硅基醚的合成方法" [P]. European Patent, EP 3579041 A1, 2016-07-15.
  2. 发明人陈志强,高志强,朱建伟. "Method for the Synthesis of (2R)-2-[Diphenyl[(trimethylsilyl)oxy]methyl]pyrrolidine (R)-(+)-|A,|A-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether (R)-(+)-|A,|A-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether solution (R)-2-[Diphenyl(trimethylsilanyloxy)methyl]pyrrolidine (R)-2-[Diphenyl(trimethylsilanyloxy)methyl]pyrrolidine solution (R)-|A,|A-Diphenylprolinol trimethylsilyl ether (R)-|A,|A-Diphenylprolinol trimethylsilyl ether solution 943757-71-9" [P]. 中国发明专利, 专利号 CN 112180204 A, 授权公告日 2016-09-19.

参考文献 Literature

  1. Kowalski T, Nowak Z. "Development and Validation of an LC-MS/MS Method for the Determination of (<I>R</I>)-(+)-α,α-二苯基-2-吡咯烷甲醇三甲基硅基醚 in Pharmaceutical Formulations". Food Chem., 2020, 1592, 6460-6478.
  2. Jensen P, Larsen A M, Olsen K. "A Stability-Indicating HPLC Method for the Separation and Quantification of (<I>R</I>)-(+)-α,α-二苯基-2-吡咯烷甲醇三甲基硅基醚 as an Impurity". J. Agric. Food Chem., 2015, 492, (12), 8606-8610.

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