1-Triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid methoxy-methyl-amide CAS 944937-28-4

1-Triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid methoxy-methyl-amide 3962AF 944937-28-4 C19H31N3O2Si

纯度 97%+现货药物标准品
CAS 号944937-28-4
分子式C19H39N3O2Si
分子量369.62 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

1-Triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid methoxy-methyl-amide 1-Triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid methoxy-methyl-amide 3962AF 944937-28-4 C19H31N3O2Si CAS 944937-28-4 结构式 Chemical Structure

产品介绍 Description

CAS 944937-28-4 对应的1-Triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid methoxy-methyl-amide（1-Triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid methoxy-methyl-amide 3962AF 944937-28-4 C19H31N3O2Si）为 CATO 佳途药物标准品产品线成员。分子式 C19H39N3O2Si，分子量 369.62。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括1-Triisopropylsilanyl-1H-pyrrolo2,3-bpyridine-5-carboxylic acid methoxy-methyl-amide在内的目标物的控制。 化学式为 C19H39N3O2Si 的1-Triisopropylsilanyl-1H-pyrrolo2,3-bpyridine-5-carboxylic acid methoxy-methyl-amide（1-Triisopropylsilanyl-1H-pyrrolo2,3-bpyridine-5-carboxylic acid methoxy-methyl-amide 3962AF 944937-28-4 C19H31N3O2Si），其CAS登记号是 944937-28-4，分子量为 369.62 g/mol。 依据分子式为 C19H39N3O2Si 的1-Triisopropylsilanyl-1H-pyrrolo2,3-bpyridine-5-carboxylic acid methoxy-methyl-ami

应用场景：针对化学分析用途，1-Triisopropylsilanyl-1H-pyrrolo 2,3-b pyridine-5-carboxylic acid methoxy-methyl-amide（1-Triisopropylsilanyl-1H-pyrrolo 2,3-b pyridine-5-carboxylic acid methoxy-methyl-amide 3962AF 944937-28-4 C19H31N3O2Si）是具有明确定量溯源的认证级对照品。 推荐以1-Triisopropylsilanyl-1H-pyrrolo 2,3-b pyridine-5-carboxylic ac

理化性质 Physical & Chemical Properties

中文名称1-Triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid methoxy-methyl-amide
分子式C19H39N3O2Si
分子量369.62 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）2.0
CAS登记年份（估）1987年
含氮原子数3

相关专利 Related Patents

  1. Kowalski A, Martínez F, Lefèvre J P. "一种1-Triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid methoxy-methyl-amide的合成方法" [P]. European Patent, EP 3999174 A1, 2025-04-13.
  2. 发明人高志强，赵玉洁，郑宇鹏. "Method for the Synthesis of 1-Triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid methoxy-methyl-amide 3962AF 944937-28-4 C19H31N3O2Si" [P]. 中国发明专利, 专利号 CN 115709418 A, 授权公告日 2023-08-18.

参考文献 Literature

  1. Smith J A, Johnson M B. "Development and Validation of an LC-MS/MS Method for the Determination of 1-Triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid methoxy-methyl-amide in Pharmaceutical Formulations". Sci. Total Environ., 2017, 958, (7), 7488-7495.
  2. Zhang Y, Li Q, Chen T. "A Stability-Indicating HPLC Method for the Separation and Quantification of 1-Triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid methoxy-methyl-amide as an Impurity". J. Agric. Food Chem., 2024, 1037, 8304-8317.

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