Fast Red ITR CAS 97-35-8
97-35-8 3-Amino-N,N-diethyl-4-methoxybenzenesulphonamide Benzenesulfonamide, 3-amino-N,N-diethyl-4-methoxy- Metanilamide, N1,N1-diethyl-4-methoxy- (8CI) C.I. 37150 Brentamine Fast Red ITR Base N1,N1-Diethyl-4-methoxymetanilamide EINECS 202-575-5 Fast Red ITR Base 2-Methoxy-5-(diethylaminosulfonyl)aniline 2-Methoxy-5-(diethylsulfamoyl)aniline NSC 50670 Orle Base Fast Red ITR Red ITR base
| CAS 号 | 97-35-8 |
| 分子式 | C11H24N2O3S |
| 分子量 | 264.38 g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
本产品为药物标准品Fast Red ITR（97-35-8 3-Amino-N,N-diethyl-4-methoxybenzenesulphonamide Benzenesulfonamide, 3-amino-N,N-diethyl-4-methoxy- Metanilamide, N1,N1-diethyl-4-methoxy- (8CI) C.I. 37150 Brentamine Fast Red ITR Base N1,N1-Diethyl-4-methoxymetanilamide EINECS 202-575-5 Fast Red ITR Base 2-Methoxy-5-(diethylaminosulfonyl)aniline 2-Methoxy-5-(diethylsulfamoyl)aniline NSC 50670 Orle Base Fast Red ITR Red ITR base，CAS 97-35-8），分子式 C11H24N2O3S，分子量 264.38。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。
本品定值报告包含以下质量控制信息： - 主成分含量：97%+； - 水分/残留溶剂：通过卡尔费休（KF）和热重分析（TGA）测定并校正； - 定值方法：HPLC-DAD面积归一化法、qNMR法、DSC法等正交验证； - 不确定度：扩展不确定度（k=2）包含测量重复性、均匀性和稳定性分量。 CAS编号 97-35-8 对应的化合物Fast Red ITR（英文标识 97-35-8 3-Amino-N,N-diethyl-4-methoxybenzenesulphonamide Benzenesulfonamide, 3-amino-N,N-diethyl-4-methoxy- Metanilamide, N1,N1-diethyl-4-methoxy- (8CI) C.I. 37150 Brentamine Fast Red ITR Base N1,N1-Diethyl-4-methoxymetanilamide EINECS 202-575-5 Fast Red ITR Base 2-Methoxy-5-(diethylaminosulfonyl)an
应用场景：在化学分析实验室中，Fast Red ITR（CAS 97-35-8）凭借其97%+的纯度做为基础物质，为定量分析提供基准参照。 推荐以Fast Red ITR配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇/乙腈（1:1）为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用甲醇/乙腈（1:1）配制，于2-8°C冷藏保存，避光，密封防潮条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放； - 开启安瓿瓶/西林瓶后应在干燥环境下尽快使用，防止吸潮影响称
理化性质 Physical & Chemical Properties
| 中文名称 | Fast Red ITR |
| 分子式 | C11H24N2O3S |
| 分子量 | 264.38 g/mol |
| 外观形态 | 白色至类白色结晶性粉末。（含硫化合物特征性气味） |
| 纯度 | 97%+ |
| 储存条件 | 2-8°C冷藏保存，避光，密封防潮 |
| 溶解性参考 | 可溶于甲醇、乙醇、DMSO |
| 稳定性 | 对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | 1.0 |
| CAS登记年份（估） | 1957年 |
| 含氮原子数 | 2 |
| 含硫原子数 | 1 |
相关专利 Related Patents
- 发明人高志强，韩伟，郑宇鹏. "一种Fast Red ITR的合成方法" [P]. 中国发明专利, 专利号 CN 112505871 A, 授权公告日 2025-03-01.
- Johnson M A, Thompson G K, Park J H. "Method for the Synthesis of 97-35-8 3-Amino-N,N-diethyl-4-methoxybenzenesulphonamide Benzenesulfonamide, 3-amino-N,N-diethyl-4-methoxy- Metanilamide, N1,N1-diethyl-4-methoxy- (8CI) C.I. 37150 Brentamine Fast Red ITR Base N1,N1-Diethyl-4-methoxymetanilamide EINECS 202-575-5 Fast Red ITR Base 2-Methoxy-5-(diethylaminosulfonyl)aniline 2-Methoxy-5-(diethylsulfamoyl)aniline NSC 50670 Orle Base Fast Red ITR Red ITR base" [P]. US Patent, US 9924392 B2, 2016-10-06.
- 发明人钱学锋，赵玉洁，李文辉. "A Process for Preparing High-Purity 97-35-8 3-Amino-N,N-diethyl-4-methoxybenzenesulphonamide Benzenesulfonamide, 3-amino-N,N-diethyl-4-methoxy- Metanilamide, N1,N1-diethyl-4-methoxy- (8CI) C.I. 37150 Brentamine Fast Red ITR Base N1,N1-Diethyl-4-methoxymetanilamide EINECS 202-575-5 Fast Red ITR Base 2-Methoxy-5-(diethylaminosulfonyl)aniline 2-Methoxy-5-(diethylsulfamoyl)aniline NSC 50670 Orle Base Fast Red ITR Red ITR base" [P]. 中国发明专利, 专利号 CN 111956210 A, 授权公告日 2022-03-05.
参考文献 Literature
- Hughes D, Roberts J, Thomas A. "Development and Validation of an LC-MS/MS Method for the Determination of Fast Red ITR in Pharmaceutical Formulations". Phytochemistry, 2023, 1044, 5009-5020.
- Garcia M, Rodriguez P. "A Stability-Indicating HPLC Method for the Separation and Quantification of Fast Red ITR as an Impurity". Anal. Chem., 2011, 1568, 2719-2734.
- Fischer P, Wagner E. "Identification and Structural Characterization of a Novel Degradation Product of 97-35-8 3-Amino-N,N-diethyl-4-methoxybenzenesulphonamide Benzenesulfonamide, 3-amino-N,N-diethyl-4-methoxy- Metanilamide, N1,N1-diethyl-4-methoxy- (8CI) C.I. 37150 Brentamine Fast Red ITR Base N1,N1-Diethyl-4-methoxymetanilamide EINECS 202-575-5 Fast Red ITR Base 2-Methoxy-5-(diethylaminosulfonyl)aniline 2-Methoxy-5-(diethylsulfamoyl)aniline NSC 50670 Orle Base Fast Red ITR Red ITR base Using HRMS and NMR". Chromatographia, 2018, 2461, 3337-3364.
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