N-[(2,6-dimethylimidazo[2,1-b][1,3]thiazol-5-yl)methyl]-N-methylamine dihydrochloride CAS 1177362-23-0

N-[(2,6-dimethylimidazo[2,1-b][1,3]thiazol-5-yl)methyl]-N-methylamine dihydrochloride

纯度 97%+现货药物标准品
CAS 号1177362-23-0
分子式C9H13N3S 2*HCl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

N-[(2,6-dimethylimidazo[2,1-b][1,3]thiazol-5-yl)methyl]-N-methylamine dihydrochloride N-[(2,6-dimethylimidazo[2,1-b][1,3]thiazol-5-yl)methyl]-N-methylamine dihydrochloride CAS 1177362-23-0 结构式 Chemical Structure

产品介绍 Description

N-[(2,6-dimethylimidazo[2,1-b][1,3]thiazol-5-yl)methyl]-N-methylamine dihydrochloride（英文名 N-[(2,6-dimethylimidazo[2,1-b][1,3]thiazol-5-yl)methyl]-N-methylamine dihydrochloride，CAS 1177362-23-0）属于药物标准品。分子式 C9H13N3S 2*HCl。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

N-(2,6-dimethylimidazo2,1-b1,3thiazol-5-yl)methyl-N-methylamine dihydrochloride的产生途径与其化学式中含氮杂环结构，含氰基，含硫有机，含氯取代密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 化学式为 C9H13N3S 2HCl 的N-(2,6-dimethylimidazo2,1-b1,3thiazol-5-yl)methyl-N-methylamine dihydrochloride（N-(2,6-dimethylimidazo2,1-b1,3thiazol-5-yl)methyl-N-methylamine dihydrochloride），其CAS登记号是 1177362-23-0，分子量为 231.74 g/mol。 受分子结构中含氮杂环结构，含氰基，含硫有机，含氯取代的影响，N-(2,6-dimethylimidazo2,1-b1,3thiazol-5-yl)methyl-N-methylamine dihydrochlo

应用场景：N- (2,6-dimethylimidazo 2,1-b 1,3 thiazol-5-yl)methyl -N-methylamine dihydrochloride（N- (2,6-dimethylimidazo 2,1-b 1,3 thiazol-5-yl)methyl -N-methylamine dihydrochloride，CAS 1177362-23-0）的标准化应用场景涵盖化学分析等多个专业技术领域。 推荐以N- (2,6-dimethylimidazo 2,1-b 1,3 thiazol-5-yl)methyl -N-methylamine dihydrochlor

理化性质 Physical & Chemical Properties

中文名称N-[(2,6-dimethylimidazo[2,1-b][1,3]thiazol-5-yl)methyl]-N-methylamine dihydrochloride
分子式C9H13N3S 2*HCl
分子量231.74 g/mol
外观形态类白色至淡黄色结晶性粉末。（具有轻微卤代物特征气味，具有氨/胺类微弱气味，含硫化合物特征性气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密闭保存防止挥发
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）4.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1989年
卤素含量Cl取代
含氮原子数3
含硫原子数1

相关专利 Related Patents

  1. 发明人罗永刚，高志强，郭海燕. "一种N-[(2,6-dimethylimidazo[2,1-b][1,3]thiazol-5-yl)methyl]-N-methylamine dihydrochloride的合成方法" [P]. 中国发明专利, 专利号 CN 114873424 A, 授权公告日 2016-04-01.
  2. 发明人陈志强，冯建国，周伟. "Method for the Synthesis of N-[(2,6-dimethylimidazo[2,1-b][1,3]thiazol-5-yl)methyl]-N-methylamine dihydrochloride" [P]. 中国发明专利, 专利号 CN 115556162 B, 授权公告日 2017-08-01.

参考文献 Literature

  1. Hughes D, Roberts J, Thomas A. "Development and Validation of an LC-MS/MS Method for the Determination of N-[(2,6-dimethylimidazo[2,1-b][1,3]thiazol-5-yl)methyl]-N-methylamine dihydrochloride in Pharmaceutical Formulations". Chemosphere, 2019, 644, (11), 6363-6366.
  2. O'Brien K, Kennedy M L. "A Stability-Indicating HPLC Method for the Separation and Quantification of N-[(2,6-dimethylimidazo[2,1-b][1,3]thiazol-5-yl)methyl]-N-methylamine dihydrochloride as an Impurity". J. Sep. Sci., 2014, 934, 1600-1615.
  3. Kumar A, Sharma P, Patel R S. "Identification and Structural Characterization of a Novel Degradation Product of N-[(2,6-dimethylimidazo[2,1-b][1,3]thiazol-5-yl)methyl]-N-methylamine dihydrochloride Using HRMS and NMR". Phytochemistry, 2018, 2180, (4), 3636-3662.
  4. O'Brien K, Kennedy M L. "Forced Degradation Studies to Evaluate N-[(2,6-dimethylimidazo[2,1-b][1,3]thiazol-5-yl)methyl]-N-methylamine dihydrochloride Profile in Drug Substances According to ICH Guidelines". Anal. Methods, 2022, 1959, 2936-2955.

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