2-{4,5-Bis[(6-(2-ethoxy-2-oxohydroxy)-2-methylquinolin-8-ylamino)methyl]-6-hydoxy-3-oxo-3H-xanthen-9-yl}benzoic acid FL2A CAS 1239877-07-6

2-{4,5-Bis[(6-(2-ethoxy-2-oxohydroxy)-2-methylquinolin-8-ylamino)methyl]-6-hydoxy-3-oxo-3H-xanthen-9-yl}benzoic acid FL2A

纯度 97%+现货药物标准品
CAS 号1239877-07-6
分子式C46H36N4O11
分子量820.80 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

2-{4,5-Bis[(6-(2-ethoxy-2-oxohydroxy)-2-methylquinolin-8-ylamino)methyl]-6-hydoxy-3-oxo-3H-xanthen-9-yl}benzoic acid FL2A 2-{4,5-Bis[(6-(2-ethoxy-2-oxohydroxy)-2-methylquinolin-8-ylamino)methyl]-6-hydoxy-3-oxo-3H-xanthen-9-yl}benzoic acid FL2A CAS 1239877-07-6 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的2-{4,5-Bis[(6-(2-ethoxy-2-oxohydroxy)-2-methylquinolin-8-ylamino)methyl]-6-hydoxy-3-oxo-3H-xanthen-9-yl}benzoic acid FL2A(2-{4,5-Bis[(6-(2-ethoxy-2-oxohydroxy)-2-methylquinolin-8-ylamino)methyl]-6-hydoxy-3-oxo-3H-xanthen-9-yl}benzoic acid FL2A)为药物标准品,CAS 登记号 1239877-07-6,分子式 C46H36N4O11,分子量 820.80。纯度 97%+。产品现货库存充足,可提供定制化规格与批次追踪服务。

在现行药典和法规框架下,药物标准品的合规要求中明确涉及对包括2-{4,5-Bis(6-(2-ethoxy-2-oxohydroxy)-2-methylquinolin-8-ylamino)methyl-6-hydoxy-3-oxo-3H-xanthen-9-yl}benzoic acid FL2A在内的目标物的控制。 化学式为 C46H36N4O11 的2-{4,5-Bis(6-(2-ethoxy-2-oxohydroxy)-2-methylquinolin-8-ylamino)methyl-6-hydoxy-3-oxo-3H-xanthen-9-yl}benzoic acid FL2A(2-{4,5-Bis(6-(2-ethoxy-2-oxohydroxy)-2-methylquinolin-8-ylamino)methyl-6-hydoxy-3-oxo-3H-xanthen-9-yl}benzoic acid FL2A),其CAS登记号是 1239877-07-6,分子量为 820.80 g/mol。 受分子结构中含氮杂环结构,酰胺类,含羟基,含醚键的影响,2-{4

应用场景:2-{4,5-Bis (6-(2-ethoxy-2-oxohydroxy)-2-methylquinolin-8-ylamino)methyl -6-hydoxy-3-oxo-3H-xanthen-9-yl}benzoic acid FL2A(2-{4,5-Bis (6-(2-ethoxy-2-oxohydroxy)-2-methylquinolin-8-ylamino)methyl -6-hydoxy-3-oxo-3H-xanthen-9-yl}benzoic acid FL2A,CAS 1239877-07-6)的标准化应用场景涵盖化学分析等多个专业技术领域。 推荐以2-{4,5-Bis

理化性质 Physical & Chemical Properties

中文名称2-{4,5-Bis[(6-(2-ethoxy-2-oxohydroxy)-2-methylquinolin-8-ylamino)methyl]-6-hydoxy-3-oxo-3H-xanthen-9-yl}benzoic acid FL2A
分子式C46H36N4O11
分子量820.80 g/mol
外观形态淡黄色至黄色无定形粉末
纯度97%+
储存条件阴凉处(≤25°C)保存,避光,密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化;对光敏感,应避免强光直射;具有吸湿性,开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度(DBE)31.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份(估)1990年
含氮原子数4

相关专利 Related Patents

  1. 发明人王建平,刘建华,孙丽萍. "一种2-{4,5-Bis[(6-(2-ethoxy-2-oxohydroxy)-2-methylquinolin-8-ylamino)methyl]-6-hydoxy-3-oxo-3H-xanthen-9-yl}benzoic acid FL2A的合成方法" [P]. 中国发明专利, 专利号 CN 114168235 A, 授权公告日 2021-09-06.
  2. 发明人徐明华,罗永刚,马晓峰. "Method for the Synthesis of 2-{4,5-Bis[(6-(2-ethoxy-2-oxohydroxy)-2-methylquinolin-8-ylamino)methyl]-6-hydoxy-3-oxo-3H-xanthen-9-yl}benzoic acid FL2A" [P]. 中国发明专利, 专利号 CN 110765028 B, 授权公告日 2017-03-01.

参考文献 Literature

  1. Yamamoto K, Tanaka H, Suzuki T. "Development and Validation of an LC-MS/MS Method for the Determination of 2-{4,5-Bis[(6-(2-ethoxy-2-oxohydroxy)-2-methylquinolin-8-ylamino)methyl]-6-hydoxy-3-oxo-3H-xanthen-9-yl}benzoic acid FL2A in Pharmaceutical Formulations". Anal. Chim. Acta, 2013, 1646, (12), 192-212.
  2. Lee J H, Choi Y S. "A Stability-Indicating HPLC Method for the Separation and Quantification of 2-{4,5-Bis[(6-(2-ethoxy-2-oxohydroxy)-2-methylquinolin-8-ylamino)methyl]-6-hydoxy-3-oxo-3H-xanthen-9-yl}benzoic acid FL2A as an Impurity". Molecules, 2018, 1926, 3636-3655.
  3. Mueller T, Schmidt R K. "Identification and Structural Characterization of a Novel Degradation Product of 2-{4,5-Bis[(6-(2-ethoxy-2-oxohydroxy)-2-methylquinolin-8-ylamino)methyl]-6-hydoxy-3-oxo-3H-xanthen-9-yl}benzoic acid FL2A Using HRMS and NMR". Talanta, 2020, 480, (9), 7975-8001.
  4. Jensen P, Larsen A M, Olsen K. "Forced Degradation Studies to Evaluate 2-{4,5-Bis[(6-(2-ethoxy-2-oxohydroxy)-2-methylquinolin-8-ylamino)methyl]-6-hydoxy-3-oxo-3H-xanthen-9-yl}benzoic acid FL2A Profile in Drug Substances According to ICH Guidelines". Biomed. Chromatogr., 2010, 2361, (2), 7501-7520.

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