(Acetonitrile)[(2-di-<I>tert</I>-butylphosphino-3,4,5,6-tetramethyl)-2′,4′,6′-triisopropylbiphenyl]gold(I) hexafluoroantimonate CAS 1334547-72-6

(Acetonitrile)[(2-di-<I>tert</I>-butylphosphino-3,4,5,6-tetramethyl)-2′,4′,6′-triisopropylbiphenyl]gold(I) hexafluoroantimonate

纯度 97%+现货药物标准品
CAS 号1334547-72-6
分子式C33H65P C2H3AuN F6Sb
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

(Acetonitrile)[(2-di-<I>tert</I>-butylphosphino-3,4,5,6-tetramethyl)-2′,4′,6′-triisopropylbiphenyl]gold(I) hexafluoroantimonate (Acetonitrile)[(2-di-<I>tert</I>-butylphosphino-3,4,5,6-tetramethyl)-2′,4′,6′-triisopropylbiphenyl]gold(I) hexafluoroantimonate CAS 1334547-72-6 结构式 Chemical Structure

产品介绍 Description

(Acetonitrile)[(2-di-<I>tert</I>-butylphosphino-3,4,5,6-tetramethyl)-2′,4′,6′-triisopropylbiphenyl]gold(I) hexafluoroantimonate（(Acetonitrile)[(2-di-<I>tert</I>-butylphosphino-3,4,5,6-tetramethyl)-2′,4′,6′-triisopropylbiphenyl]gold(I) hexafluoroantimonate，CAS 号 1334547-72-6）是 CATO 佳途自主生产的药物标准品，分子式 C33H65P C2H3AuN F6Sb。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括(Acetonitrile)(2-di-<I>tert</I>-butylphosphino-3,4,5,6-tetramethyl)-2′,4′,6′-triisopropylbiphenylgold(I) hexafluoroantimonate在内的目标物的控制。 (Acetonitrile)(2-di-<I>tert</I>-butylphosphino-3,4,5,6-tetramethyl)-2′,4′,6′-triisopropylbiphenylgold(I) hexafluoroantimonate（(Acetonitrile)(2-di-<I>tert</I>-butylphosphino-3,4,5,6-tetramethyl)-2′,4′,6′-triisopropylbiphenylgold(I) hexafluoroantimonate），CAS注册编号 1334547-72-6，化学分子式为 C33H65P C2H3AuN F6Sb，分子量 966.63 g/mol。 (Aceto

应用场景：针对化学分析用途，(Acetonitrile) (2-di-<I>tert</I>-butylphosphino-3,4,5,6-tetramethyl)-2′,4′,6′-triisopropylbiphenyl gold(I) hexafluoroantimonate（(Acetonitrile) (2-di-<I>tert</I>-butylphosphino-3,4,5,6-tetramethyl)-2′,4′,6′-triisopropylbiphenyl gold(I) hexafluoroantimonate）是具有明确定量溯源的认证级对照品。 推荐以(Acetonitrile

理化性质 Physical & Chemical Properties

中文名称(Acetonitrile)[(2-di-<I>tert</I>-butylphosphino-3,4,5,6-tetramethyl)-2′,4′,6′-triisopropylbiphenyl]gold(I) hexafluoroantimonate
分子式C33H65P C2H3AuN F6Sb
分子量966.63 g/mol
外观形态白色至类白色无定形粉末。（具有轻微卤代物特征气味，挥发性较低）
纯度97%+
储存条件室温保存，避光
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）-0.5
CAS登记年份（估）1991年
卤素含量F取代
含氮原子数1

相关专利 Related Patents

  1. 发明人韩伟，周伟，赵玉洁. "一种(Acetonitrile)[(2-di-<I>tert</I>-butylphosphino-3,4,5,6-tetramethyl)-2′,4′,6′-triisopropylbiphenyl]gold(I) hexafluoroantimonate的合成方法" [P]. 中国发明专利, 专利号 CN 116721732 A, 授权公告日 2020-04-14.
  2. Johansson L, Sørensen M, Nowak P. "Method for the Synthesis of (Acetonitrile)[(2-di-<I>tert</I>-butylphosphino-3,4,5,6-tetramethyl)-2′,4′,6′-triisopropylbiphenyl]gold(I) hexafluoroantimonate" [P]. European Patent, EP 3513469 A1, 2018-08-17.
  3. Anderson J P, Hughes D C, Chen K W. "A Process for Preparing High-Purity (Acetonitrile)[(2-di-<I>tert</I>-butylphosphino-3,4,5,6-tetramethyl)-2′,4′,6′-triisopropylbiphenyl]gold(I) hexafluoroantimonate" [P]. US Patent, US 10656815 B2, 2025-02-10.

参考文献 Literature

  1. Martinez C, Lopez D R. "Development and Validation of an LC-MS/MS Method for the Determination of (Acetonitrile)[(2-di-<I>tert</I>-butylphosphino-3,4,5,6-tetramethyl)-2′,4′,6′-triisopropylbiphenyl]gold(I) hexafluoroantimonate in Pharmaceutical Formulations". Environ. Sci. Technol., 2020, 1466, (11), 2312-2315.
  2. Yamamoto K, Tanaka H, Suzuki T. "A Stability-Indicating HPLC Method for the Separation and Quantification of (Acetonitrile)[(2-di-<I>tert</I>-butylphosphino-3,4,5,6-tetramethyl)-2′,4′,6′-triisopropylbiphenyl]gold(I) hexafluoroantimonate as an Impurity". J. Chromatogr. A, 2016, 248, 4331-4335.
  3. Garcia M, Rodriguez P. "Identification and Structural Characterization of a Novel Degradation Product of (Acetonitrile)[(2-di-<I>tert</I>-butylphosphino-3,4,5,6-tetramethyl)-2′,4′,6′-triisopropylbiphenyl]gold(I) hexafluoroantimonate Using HRMS and NMR". Talanta, 2019, 870, (3), 2786-2810.
  4. Fischer P, Wagner E. "Forced Degradation Studies to Evaluate (Acetonitrile)[(2-di-<I>tert</I>-butylphosphino-3,4,5,6-tetramethyl)-2′,4′,6′-triisopropylbiphenyl]gold(I) hexafluoroantimonate Profile in Drug Substances According to ICH Guidelines". Rapid Commun. Mass Spectrom., 2015, 1920, (3), 2809-2814.

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