CAS 171179-06-9

171179-06-9 4-(3-bromoanilino)-6-(methylamino)pyrido[3,4-d]pyrimidine 4-(3-bromoanilino)-6-methylaminopyrido[3,4-d]pyrimidine 4-[(3-bromophenyl)amino]-6-(methylamino)pyrido[3,4-d]pyrimidine CHEBI:92843 N(4)-(3-bromophenyl)-N(6)-methylpyrido[3,4-d]pyrimidine-4,6-diamine PD 158780 PD-158780 PD158780

纯度 97%+现货药物标准品
CAS 号171179-06-9
分子式C14H12BrN5
分子量330.18 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

171179-06-9 4-(3-bromoanilino)-6-(methylamino)pyrido[3,4-d]pyrimidine 4-(3-bromoanilino)-6-methylaminopyrido[3,4-d]pyrimidine 4-[(3-bromophenyl)amino]-6-(methylamino)pyrido[3,4-d]pyrimidine CHEBI:92843 N(4)-(3-bromophenyl)-N(6)-methylpyrido[3,4-d]pyrimidine-4,6-diamine PD 158780 PD-158780 PD158780 CAS 171179-06-9 结构式 Chemical Structure

产品介绍 Description

（171179-06-9 4-(3-bromoanilino)-6-(methylamino)pyrido[3,4-d]pyrimidine 4-(3-bromoanilino)-6-methylaminopyrido[3,4-d]pyrimidine 4-[(3-bromophenyl)amino]-6-(methylamino)pyrido[3,4-d]pyrimidine CHEBI:92843 N(4)-(3-bromophenyl)-N(6)-methylpyrido[3,4-d]pyrimidine-4,6-diamine PD 158780 PD-158780 PD158780，CAS 号 171179-06-9）是 CATO 佳途自主生产的药物标准品，分子式 C14H12BrN5，分子量 330.18。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括在内的目标物的控制。 （171179-06-9 4-(3-bromoanilino)-6-(methylamino)pyrido3,4-dpyrimidine 4-(3-bromoanilino)-6-methylaminopyrido3,4-dpyrimidine 4-(3-bromophenyl)amino-6-(methylamino)pyrido3,4-dpyrimidine CHEBI:92843 N(4)-(3-bromophenyl)-N(6)-methylpyrido3,4-dpyrimidine-4,6-diamine PD 158780 PD-158780 PD158780），CAS注册编号 171179-06-9，化学分子式为 C14H12BrN5，分子量 330.18 g/mol。 受分子结构中含氮杂环结构，含氰基，含溴取代的影响，表现为淡黄色至黄色结晶性粉末。（具有轻微卤代物特征气味）。其固体形态的物理化学属性——包括330.18 g/mol的分子量——对于选择合适的样品前处理

应用场景：（171179-06-9 4-(3-bromoanilino)-6-(methylamino)pyrido 3,4-d pyrimidine 4-(3-bromoanilino)-6-methylaminopyrido 3,4-d pyrimidine 4- (3-bromophenyl)amino -6-(methylamino)pyrido 3,4-d pyrimidine CHEBI:92843 N(4)-(3-bromophenyl)-N(6)-methylpyrido 3,4-d pyrimidine-4,6-diamine PD 158780 PD-158780 PD158780）

理化性质 Physical & Chemical Properties

中文名称
分子式C14H12BrN5
分子量330.18 g/mol
外观形态淡黄色至黄色结晶性粉末。（具有轻微卤代物特征气味）
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）11.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）2005年
卤素含量Br取代
含氮原子数5

相关专利 Related Patents

  1. Mueller T, Park J H, Johnson M A. "一种的合成方法" [P]. US Patent, US 9944944 B2, 2024-05-15.
  2. 发明人何建平，张德明，周伟. "Method for the Synthesis of 171179-06-9 4-(3-bromoanilino)-6-(methylamino)pyrido[3,4-d]pyrimidine 4-(3-bromoanilino)-6-methylaminopyrido[3,4-d]pyrimidine 4-[(3-bromophenyl)amino]-6-(methylamino)pyrido[3,4-d]pyrimidine CHEBI:92843 N(4)-(3-bromophenyl)-N(6)-methylpyrido[3,4-d]pyrimidine-4,6-diamine PD 158780 PD-158780 PD158780" [P]. 中国发明专利, 专利号 CN 111898540 B, 授权公告日 2022-06-13.

参考文献 Literature

  1. Zhou X P, Huang L, Wu G. "Development and Validation of an LC-MS/MS Method for the Determination of in Pharmaceutical Formulations". Rapid Commun. Mass Spectrom., 2021, 1402, 7574-7592.
  2. Zhang Y, Li Q, Chen T. "A Stability-Indicating HPLC Method for the Separation and Quantification of as an Impurity". Talanta, 2018, 1924, 3673-3693.
  3. Smith J A, Johnson M B. "Identification and Structural Characterization of a Novel Degradation Product of 171179-06-9 4-(3-bromoanilino)-6-(methylamino)pyrido[3,4-d]pyrimidine 4-(3-bromoanilino)-6-methylaminopyrido[3,4-d]pyrimidine 4-[(3-bromophenyl)amino]-6-(methylamino)pyrido[3,4-d]pyrimidine CHEBI:92843 N(4)-(3-bromophenyl)-N(6)-methylpyrido[3,4-d]pyrimidine-4,6-diamine PD 158780 PD-158780 PD158780 Using HRMS and NMR". J. Nat. Prod., 2017, 2429, 8761-8764.

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