2-oxo-2-phenylethyl 6-cyclopropyl-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylate CAS 1795274-20-2

2-oxo-2-phenylethyl 6-cyclopropyl-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylate

纯度 97%+现货药物标准品
CAS 号1795274-20-2
分子式C19H16N2O4
分子量336.34 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

2-oxo-2-phenylethyl 6-cyclopropyl-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylate 2-oxo-2-phenylethyl 6-cyclopropyl-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylate CAS 1795274-20-2 结构式 Chemical Structure

产品介绍 Description

本产品为药物标准品2-oxo-2-phenylethyl 6-cyclopropyl-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylate（2-oxo-2-phenylethyl 6-cyclopropyl-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylate，CAS 1795274-20-2），分子式 C19H16N2O4，分子量 336.34。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。

2-oxo-2-phenylethyl 6-cyclopropyl-3-methyl-1,2oxazolo5,4-bpyridine-4-carboxylate的产生途径与其化学式中黄酮骨架，酰胺类，含羟基，含醚键密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 2-oxo-2-phenylethyl 6-cyclopropyl-3-methyl-1,2oxazolo5,4-bpyridine-4-carboxylate（2-oxo-2-phenylethyl 6-cyclopropyl-3-methyl-1,2oxazolo5,4-bpyridine-4-carboxylate），CAS注册编号 1795274-20-2，化学分子式为 C19H16N2O4，分子量 336.34 g/mol。 依据分子式为 C19H16N2O4 的2-oxo-2-phenylethyl 6-cyclopropyl-3-methyl-1,2oxazolo5,4-bpyridine-4-carboxylate结构特征，其分子内含黄酮骨架，酰胺类，含

应用场景：针对化学分析用途，2-oxo-2-phenylethyl 6-cyclopropyl-3-methyl- 1,2 oxazolo 5,4-b pyridine-4-carboxylate（2-oxo-2-phenylethyl 6-cyclopropyl-3-methyl- 1,2 oxazolo 5,4-b pyridine-4-carboxylate）是具有明确定量溯源的认证级对照品。 推荐以2-oxo-2-phenylethyl 6-cyclopropyl-3-methyl- 1,2 oxazolo 5,4-b pyridine-4-carboxylate配制标准系列工作溶液，用于建立

理化性质 Physical & Chemical Properties

中文名称2-oxo-2-phenylethyl 6-cyclopropyl-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylate
分子式C19H16N2O4
分子量336.34 g/mol
外观形态淡黄色至黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）13.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1994年
含氮原子数2

相关专利 Related Patents

  1. 发明人王建平，杨光，李文辉. "一种2-oxo-2-phenylethyl 6-cyclopropyl-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylate的合成方法" [P]. 中国发明专利, 专利号 CN 108596329 A, 授权公告日 2025-01-10.
  2. 发明人徐明华，钱学锋，马晓峰. "Method for the Synthesis of 2-oxo-2-phenylethyl 6-cyclopropyl-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylate" [P]. 中国发明专利, 专利号 CN 109922868 B, 授权公告日 2015-03-26.

参考文献 Literature

  1. Zhou X P, Huang L, Wu G. "Development and Validation of an LC-MS/MS Method for the Determination of 2-oxo-2-phenylethyl 6-cyclopropyl-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylate in Pharmaceutical Formulations". J. Sep. Sci., 2025, 1167, (1), 5266-5285.
  2. Fischer P, Wagner E. "A Stability-Indicating HPLC Method for the Separation and Quantification of 2-oxo-2-phenylethyl 6-cyclopropyl-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylate as an Impurity". Food Chem., 2014, 1681, 7187-7205.
  3. Kumar A, Sharma P, Patel R S. "Identification and Structural Characterization of a Novel Degradation Product of 2-oxo-2-phenylethyl 6-cyclopropyl-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylate Using HRMS and NMR". Rapid Commun. Mass Spectrom., 2020, 1926, 25-38.
  4. Chen X Y, Liu M, Zhao W Q. "Forced Degradation Studies to Evaluate 2-oxo-2-phenylethyl 6-cyclopropyl-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylate Profile in Drug Substances According to ICH Guidelines". Phytochemistry, 2016, 988, (3), 3117-3132.

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