3-({[(tert-butoxy)carbonyl]amino}methyl)-1-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}cyclopentane-1-carboxylic acid CAS 1803609-23-5

3-({[(tert-butoxy)carbonyl]amino}methyl)-1-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}cyclopentane-1-carboxylic acid

纯度 97%+现货药物标准品
CAS 号1803609-23-5
分子式C27H32N2O6
分子量480.55 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

3-({[(tert-butoxy)carbonyl]amino}methyl)-1-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}cyclopentane-1-carboxylic acid 3-({[(tert-butoxy)carbonyl]amino}methyl)-1-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}cyclopentane-1-carboxylic acid CAS 1803609-23-5 结构式 Chemical Structure

产品介绍 Description

3-({[(tert-butoxy)carbonyl]amino}methyl)-1-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}cyclopentane-1-carboxylic acid（3-({[(tert-butoxy)carbonyl]amino}methyl)-1-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}cyclopentane-1-carboxylic acid）是药物分析与质量控制领域常用的药物标准品，CAS 号 1803609-23-5。分子式 C27H32N2O6，分子量 480.55。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

化学式为 C27H32N2O6 的3-({(tert-butoxy)carbonylamino}methyl)-1-{(9H-fluoren-9-ylmethoxy)carbonylamino}cyclopentane-1-carboxylic acid（3-({(tert-butoxy)carbonylamino}methyl)-1-{(9H-fluoren-9-ylmethoxy)carbonylamino}cyclopentane-1-carboxylic acid），其CAS登记号是 1803609-23-5，分子量为 480.55 g/mol。 3-({(tert-butoxy)carbonylamino}methyl)-1-{(9H-fluoren-9-ylmethoxy)carbonylamino}cyclopentane-1-carboxylic acid（C27H32N2O6）含有甾体骨架，酰胺类，含羟基，含醚键。具有较强的吸湿性，羧基赋予其一定的酸性特征，这些物理化学性质直接决定了其标准溶液的最佳配制方案和储存策略。含氮官能团的存在使该化合

应用场景：3-({ (tert-butoxy)carbonyl amino}methyl)-1-{ (9H-fluoren-9-ylmethoxy)carbonyl amino}cyclopentane-1-carboxylic acid（3-({ (tert-butoxy)carbonyl amino}methyl)-1-{ (9H-fluoren-9-ylmethoxy)carbonyl amino}cyclopentane-1-carboxylic acid）作为药物标准品，在化学分析分析领域承担着重要的角色。 推荐以3-({ (tert-butoxy)carbonyl amino}methyl

理化性质 Physical & Chemical Properties

中文名称3-({[(tert-butoxy)carbonyl]amino}methyl)-1-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}cyclopentane-1-carboxylic acid
分子式C27H32N2O6
分子量480.55 g/mol
外观形态淡黄色至黄色结晶性粉末
纯度97%+
储存条件阴凉处（≤25°C）保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）13.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1995年
含氮原子数2

相关专利 Related Patents

  1. 发明人张德明，徐明华，林芳. "一种3-({[(tert-butoxy)carbonyl]amino}methyl)-1-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}cyclopentane-1-carboxylic acid的合成方法" [P]. 中国发明专利, 专利号 CN 112947080 B, 授权公告日 2015-08-11.
  2. Thompson G K, Mueller T, Johnson M A. "Method for the Synthesis of 3-({[(tert-butoxy)carbonyl]amino}methyl)-1-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}cyclopentane-1-carboxylic acid" [P]. US Patent, US 10074462 B2, 2025-04-15.

参考文献 Literature

  1. Zhou X P, Huang L, Wu G. "Development and Validation of an LC-MS/MS Method for the Determination of 3-({[(tert-butoxy)carbonyl]amino}methyl)-1-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}cyclopentane-1-carboxylic acid in Pharmaceutical Formulations". J. Agric. Food Chem., 2010, 1064, 4250-4271.
  2. Yamamoto K, Tanaka H, Suzuki T. "A Stability-Indicating HPLC Method for the Separation and Quantification of 3-({[(tert-butoxy)carbonyl]amino}methyl)-1-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}cyclopentane-1-carboxylic acid as an Impurity". Anal. Chim. Acta, 2013, 1090, (3), 84-104.
  3. Yang F, Sun W, Liu J. "Identification and Structural Characterization of a Novel Degradation Product of 3-({[(tert-butoxy)carbonyl]amino}methyl)-1-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}cyclopentane-1-carboxylic acid Using HRMS and NMR". Food Chem., 2014, 2001, 6544-6555.

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