12:0 Lyso PC CAS 20559-18-6

(2R)-3-(dodecanoyloxy)-2-hydroxypropyl 2-(trimethylazaniumyl)ethyl phosphate 1-dodecanoyl-sn-glycero-3-phosphocholine 1-dodecanoyllysophosphatidylcholine 1-lauroyl-sn-glycero-3-phosphocholine 1-lauroyllysophosphatidylcholine 20559-18-6 CHEBI:74966 PC(12:0/0:0)

纯度 97%+现货药物标准品
CAS 号20559-18-6
分子式C20H42NO7P
分子量439.52 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

12:0 Lyso PC (2R)-3-(dodecanoyloxy)-2-hydroxypropyl 2-(trimethylazaniumyl)ethyl phosphate 1-dodecanoyl-sn-glycero-3-phosphocholine 1-dodecanoyllysophosphatidylcholine 1-lauroyl-sn-glycero-3-phosphocholine 1-lauroyllysophosphatidylcholine 20559-18-6 CHEBI:74966 PC(12:0/0:0) CAS 20559-18-6 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的12:0 Lyso PC（(2R)-3-(dodecanoyloxy)-2-hydroxypropyl 2-(trimethylazaniumyl)ethyl phosphate 1-dodecanoyl-sn-glycero-3-phosphocholine 1-dodecanoyllysophosphatidylcholine 1-lauroyl-sn-glycero-3-phosphocholine 1-lauroyllysophosphatidylcholine 20559-18-6 CHEBI:74966 PC(12:0/0:0)）为药物标准品，CAS 登记号 20559-18-6，分子式 C20H42NO7P，分子量 439.52。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括12:0 Lyso PC在内的目标物的控制。 化学式为 C20H42NO7P 的12:0 Lyso PC（(2R)-3-(dodecanoyloxy)-2-hydroxypropyl 2-(trimethylazaniumyl)ethyl phosphate 1-dodecanoyl-sn-glycero-3-phosphocholine 1-dodecanoyllysophosphatidylcholine 1-lauroyl-sn-glycero-3-phosphocholine 1-lauroyllysophosphatidylcholine 20559-18-6 CHEBI:74966 PC(12:0/0:0)），其CAS登记号是 20559-18-6，分子量为 439.52 g/mol。 受分子结构中酰胺类，含磷酸酯基，羧酸类，含羟基，含醚键的影响，12:0 Lyso PC表现为白色至类白色结晶性粉末。其固体形态的物理化学属性——包括439.52 g/mol的分子量——对于选择合适的样品前处理方法和分析技术具有指

应用场景：12:0 Lyso PC（(2R)-3-(dodecanoyloxy)-2-hydroxypropyl 2-(trimethylazaniumyl)ethyl phosphate 1-dodecanoyl-sn-glycero-3-phosphocholine 1-dodecanoyllysophosphatidylcholine 1-lauroyl-sn-glycero-3-phosphocholine 1-lauroyllysophosphatidylcholine 20559-18-6 CHEBI:74966 PC(12:0/0:0)）作为药物标准品，在化学分析分析领域承担着重要的角色。

理化性质 Physical & Chemical Properties

中文名称12:0 Lyso PC
分子式C20H42NO7P
分子量439.52 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件室温保存，避光，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）0.5
CAS登记年份（估）1962年
含氮原子数1

相关专利 Related Patents

  1. Yamamoto T, Chen K W, Mueller T. "一种12:0 Lyso PC的合成方法" [P]. US Patent, US 11092304 B2, 2019-10-04.
  2. Park J H, Roberts E F, O'Brien P Q. "Method for the Synthesis of (2R)-3-(dodecanoyloxy)-2-hydroxypropyl 2-(trimethylazaniumyl)ethyl phosphate 1-dodecanoyl-sn-glycero-3-phosphocholine 1-dodecanoyllysophosphatidylcholine 1-lauroyl-sn-glycero-3-phosphocholine 1-lauroyllysophosphatidylcholine 20559-18-6 CHEBI:74966 PC(12:0/0:0)" [P]. US Patent, US 11385109 B2, 2022-07-23.

参考文献 Literature

  1. Zhang Y, Li Q, Chen T. "Development and Validation of an LC-MS/MS Method for the Determination of 12:0 Lyso PC in Pharmaceutical Formulations". Chemosphere, 2016, 1125, (7), 4851-4867.
  2. Chen X Y, Liu M, Zhao W Q. "A Stability-Indicating HPLC Method for the Separation and Quantification of 12:0 Lyso PC as an Impurity". J. Chromatogr. A, 2011, 947, (2), 1991-2006.

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