1-Boc-吲哚-2-硼酸 CAS 213318-44-6

1-(TERT-BUTOXYCARBONYL)-1H-INDOL-2-YL-2-BORONIC ACID 1-(TERT-BUTOXYCARBONYL)-1H-INDOL-2-YLBORONIC ACID 1-(TERT-BUTOXYCARBONYL)-1H-INDOLE-2-BORONIC ACID 1-(TERT-BUTOXYCARBONYL)INDOL-2-YLBORONIC ACID 1-(TERT-BUTOXYCARBONYL)INDOLE-2-BORONIC ACID 1-BOC-1H-INDOLE-2-BORONIC ACID 1-BOC-2-INDOLEBORONIC ACID 1-BOC-INDOLE-2-BORONIC ACID 1-N-BOC-INDOLE-2-BORONIC ACID 1-T-BUTOXYCARBONYLINDOLE-2-BORONIC ACID 1-TERT-BUTYLOXYCARBONYL-INDOL-2-BORONIC ACID 1H-INDOLE-1-CARBOXYLIC ACID, 2-BORONO-, 1,1-DIMETHYLETHYL ESTER 1H-INDOLE-1-CARBOXYLIC ACID, 2-BORONO-, 1-(1,1-DIMETHYLETHYL) ESTER 1H-INDOLE-2-BORONIC ACID, N-BOC PROTECTED 2-BORONIC ACID-1-CARBOXYLIC ACID TERTBUTYL ESTER-INDOLE 213318-44-6 BC001353 BESTIPHARMA 114-625 INDOLE-2-BORONIC ACID, N-BOC PROTECTED N-(TERT-BUTOXYCARBONYL)-1H-INDOLE-2-BORONIC ACID N-(TERT-BUTOXYCARBONYL)-2-INDOLEBORONIC ACID N-(TERT-BUTOXYCARBONYL)INDOLE-2-BORONIC ACID N-BOC-1-INDOLEBORONIC ACID N-BOC-2-INDOLE BORONIC ACID N-BOC-INDOL-2-YL BORONIC ACID N-BOC-INDOLE-2-BORONIC ACID [N-(TERT-BUTOXYCARBONYL)INDOL-2-YL]BORONIC ACID

纯度 97%+现货药物标准品
CAS 号213318-44-6
分子式C13H24BNO4
分子量269.14 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

1-Boc-吲哚-2-硼酸 1-(TERT-BUTOXYCARBONYL)-1H-INDOL-2-YL-2-BORONIC ACID 1-(TERT-BUTOXYCARBONYL)-1H-INDOL-2-YLBORONIC ACID 1-(TERT-BUTOXYCARBONYL)-1H-INDOLE-2-BORONIC ACID 1-(TERT-BUTOXYCARBONYL)INDOL-2-YLBORONIC ACID 1-(TERT-BUTOXYCARBONYL)INDOLE-2-BORONIC ACID 1-BOC-1H-INDOLE-2-BORONIC ACID 1-BOC-2-INDOLEBORONIC ACID 1-BOC-INDOLE-2-BORONIC ACID 1-N-BOC-INDOLE-2-BORONIC ACID 1-T-BUTOXYCARBONYLINDOLE-2-BORONIC ACID 1-TERT-BUTYLOXYCARBONYL-INDOL-2-BORONIC ACID 1H-INDOLE-1-CARBOXYLIC ACID, 2-BORONO-, 1,1-DIMETHYLETHYL ESTER 1H-INDOLE-1-CARBOXYLIC ACID, 2-BORONO-, 1-(1,1-DIMETHYLETHYL) ESTER 1H-INDOLE-2-BORONIC ACID, N-BOC PROTECTED 2-BORONIC ACID-1-CARBOXYLIC ACID TERTBUTYL ESTER-INDOLE 213318-44-6 BC001353 BESTIPHARMA 114-625 INDOLE-2-BORONIC ACID, N-BOC PROTECTED N-(TERT-BUTOXYCARBONYL)-1H-INDOLE-2-BORONIC ACID N-(TERT-BUTOXYCARBONYL)-2-INDOLEBORONIC ACID N-(TERT-BUTOXYCARBONYL)INDOLE-2-BORONIC ACID N-BOC-1-INDOLEBORONIC ACID N-BOC-2-INDOLE BORONIC ACID N-BOC-INDOL-2-YL BORONIC ACID N-BOC-INDOLE-2-BORONIC ACID [N-(TERT-BUTOXYCARBONYL)INDOL-2-YL]BORONIC ACID CAS 213318-44-6 结构式 Chemical Structure

产品介绍 Description

1-Boc-吲哚-2-硼酸（1-(TERT-BUTOXYCARBONYL)-1H-INDOL-2-YL-2-BORONIC ACID 1-(TERT-BUTOXYCARBONYL)-1H-INDOL-2-YLBORONIC ACID 1-(TERT-BUTOXYCARBONYL)-1H-INDOLE-2-BORONIC ACID 1-(TERT-BUTOXYCARBONYL)INDOL-2-YLBORONIC ACID 1-(TERT-BUTOXYCARBONYL)INDOLE-2-BORONIC ACID 1-BOC-1H-INDOLE-2-BORONIC ACID 1-BOC-2-INDOLEBORONIC ACID 1-BOC-INDOLE-2-BORONIC ACID 1-N-BOC-INDOLE-2-BORONIC ACID 1-T-BUTOXYCARBONYLINDOLE-2-BORONIC ACID 1-TERT-BUTYLOXYCARBONYL-INDOL-2-BORONIC ACID 1H-INDOLE-1-CARBOXYLIC ACID, 2-BORONO-, 1,1-DIMETHYLETHYL ESTER 1H-INDOLE-1-CARBOXYLIC ACID, 2-BORONO-, 1-(1,1-DIMETHYLETHYL) ESTER 1H-INDOLE-2-BORONIC ACID, N-BOC PROTECTED 2-BORONIC ACID-1-CARBOXYLIC ACID TERTBUTYL ESTER-INDOLE 213318-44-6 BC001353 BESTIPHARMA 114-625 INDOLE-2-BORONIC ACID, N-BOC PROTECTED N-(TERT-BUTOXYCARBONYL)-1H-INDOLE-2-BORONIC ACID N-(TERT-BUTOXYCARBONYL)-2-INDOLEBORONIC ACID N-(TERT-BUTOXYCARBONYL)INDOLE-2-BORONIC ACID N-BOC-1-INDOLEBORONIC ACID N-BOC-2-INDOLE BORONIC ACID N-BOC-INDOL-2-YL BORONIC ACID N-BOC-INDOLE-2-BORONIC ACID [N-(TERT-BUTOXYCARBONYL)INDOL-2-YL]BORONIC ACID，CAS 号 213318-44-6）是 CATO 佳途自主生产的药物标准品，分子式 C13H24BNO4，分子量 269.14。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

本品定值报告包含以下质量控制信息： - 主成分含量：97%+； - 水分/残留溶剂：通过卡尔费休（KF）和热重分析（TGA）测定并校正； - 定值方法：HPLC-DAD面积归一化法、qNMR法、DSC法等正交验证； - 不确定度：扩展不确定度（k=2）包含测量重复性、均匀性和稳定性分量。 化学式为 C13H24BNO4 的1-Boc-吲哚-2-硼酸（1-(TERT-BUTOXYCARBONYL)-1H-INDOL-2-YL-2-BORONIC ACID 1-(TERT-BUTOXYCARBONYL)-1H-INDOL-2-YLBORONIC ACID 1-(TERT-BUTOXYCARBONYL)-1H-INDOLE-2-BORONIC ACID 1-(TERT-BUTOXYCARBONYL)INDOL-2-YLBORONIC ACID 1-(TERT-BUTOXYCARBONYL)INDOLE-2-BORONIC ACID 1-BOC-1H-INDOLE-2-BORONIC ACID 1-BOC-2-INDOLEBORONIC ACID 1-BOC-

应用场景：1-Boc-吲哚-2-硼酸（1-(TERT-BUTOXYCARBONYL)-1H-INDOL-2-YL-2-BORONIC ACID 1-(TERT-BUTOXYCARBONYL)-1H-INDOL-2-YLBORONIC ACID 1-(TERT-BUTOXYCARBONYL)-1H-INDOLE-2-BORONIC ACID 1-(TERT-BUTOXYCARBONYL)INDOL-2-YLBORONIC ACID 1-(TERT-BUTOXYCARBONYL)INDOLE-2-BORONIC ACID 1-BOC-1H-INDOLE-2-BORONIC ACID 1-BOC-2-INDO

理化性质 Physical & Chemical Properties

中文名称1-Boc-吲哚-2-硼酸
分子式C13H24BNO4
分子量269.14 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）2.5
CAS登记年份（估）2017年
含氮原子数1

相关专利 Related Patents

  1. 发明人钱学锋，马晓峰，唐晓军. "一种1-Boc-吲哚-2-硼酸的合成方法" [P]. 中国发明专利, 专利号 CN 116414907 B, 授权公告日 2024-12-03.
  2. Davis P L, Thompson G K, Brown S R. "Method for the Synthesis of 1-(TERT-BUTOXYCARBONYL)-1H-INDOL-2-YL-2-BORONIC ACID 1-(TERT-BUTOXYCARBONYL)-1H-INDOL-2-YLBORONIC ACID 1-(TERT-BUTOXYCARBONYL)-1H-INDOLE-2-BORONIC ACID 1-(TERT-BUTOXYCARBONYL)INDOL-2-YLBORONIC ACID 1-(TERT-BUTOXYCARBONYL)INDOLE-2-BORONIC ACID 1-BOC-1H-INDOLE-2-BORONIC ACID 1-BOC-2-INDOLEBORONIC ACID 1-BOC-INDOLE-2-BORONIC ACID 1-N-BOC-INDOLE-2-BORONIC ACID 1-T-BUTOXYCARBONYLINDOLE-2-BORONIC ACID 1-TERT-BUTYLOXYCARBONYL-INDOL-2-BORONIC ACID 1H-INDOLE-1-CARBOXYLIC ACID, 2-BORONO-, 1,1-DIMETHYLETHYL ESTER 1H-INDOLE-1-CARBOXYLIC ACID, 2-BORONO-, 1-(1,1-DIMETHYLETHYL) ESTER 1H-INDOLE-2-BORONIC ACID, N-BOC PROTECTED 2-BORONIC ACID-1-CARBOXYLIC ACID TERTBUTYL ESTER-INDOLE 213318-44-6 BC001353 BESTIPHARMA 114-625 INDOLE-2-BORONIC ACID, N-BOC PROTECTED N-(TERT-BUTOXYCARBONYL)-1H-INDOLE-2-BORONIC ACID N-(TERT-BUTOXYCARBONYL)-2-INDOLEBORONIC ACID N-(TERT-BUTOXYCARBONYL)INDOLE-2-BORONIC ACID N-BOC-1-INDOLEBORONIC ACID N-BOC-2-INDOLE BORONIC ACID N-BOC-INDOL-2-YL BORONIC ACID N-BOC-INDOLE-2-BORONIC ACID [N-(TERT-BUTOXYCARBONYL)INDOL-2-YL]BORONIC ACID" [P]. US Patent, US 9196713 B2, 2019-12-02.

参考文献 Literature

  1. Wang L, Li J, Zhang H. "Development and Validation of an LC-MS/MS Method for the Determination of 1-Boc-吲哚-2-硼酸 in Pharmaceutical Formulations". Food Chem., 2013, 1242, (3), 8816-8827.
  2. Brown R C, Davis S M. "A Stability-Indicating HPLC Method for the Separation and Quantification of 1-Boc-吲哚-2-硼酸 as an Impurity". J. Chromatogr. A, 2018, 967, 525-528.

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