荧光素 5(6)-异硫氰酸酯 CAS 27072-45-3
2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-5-ISOTHIOCYANATO-BENZOIC ACID 27072-45-3 5-FITC 5-FLUORESCEIN ISOTHIOCYANATE 5-FLUORESCEIN ISOTHIOCYANATE ISOMER I 5-FLUORESCEIN ISOTHIOCYANATEISOMER 5-ISOTHIOCYANATOFLUORESCEIN AS04382 FITC FITC 'ISOMER I' FITC ISOMER FITC ISOMER I FITC-CELITE(R) FITC-I FLUORESCEIN 5(6)-ISOTHIOCYANATE FLUORESCEIN 5-ISOTHIOCYANATE FLUORESCEIN 5-ISOTHIOCYANATE, ISOMER 1 FLUORESCEIN ISOMER I ISOTHIOCYANATE FLUORESCEIN ISOTHIOCYANATE ISOMER I FLUORESCEIN ISOTHIOCYANATE ISOMER I-CELITE(R) FLUORESCEIN ISOTHIOCYANATE, ISOMER 1 FLUORESCEIN-5-ISOTHIOCYANATE ISOMER I Fluorescein isothiocyanate SPECTRACOMP(TM) FITC PARTICLES
| CAS 号 | 27072-45-3 |
| 分子式 | C21H29NO5S |
| 分子量 | 407.52 g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
本产品为药物标准品荧光素 5(6)-异硫氰酸酯（2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-5-ISOTHIOCYANATO-BENZOIC ACID 27072-45-3 5-FITC 5-FLUORESCEIN ISOTHIOCYANATE 5-FLUORESCEIN ISOTHIOCYANATE ISOMER I 5-FLUORESCEIN ISOTHIOCYANATEISOMER 5-ISOTHIOCYANATOFLUORESCEIN AS04382 FITC FITC 'ISOMER I' FITC ISOMER FITC ISOMER I FITC-CELITE(R) FITC-I FLUORESCEIN 5(6)-ISOTHIOCYANATE FLUORESCEIN 5-ISOTHIOCYANATE FLUORESCEIN 5-ISOTHIOCYANATE, ISOMER 1 FLUORESCEIN ISOMER I ISOTHIOCYANATE FLUORESCEIN ISOTHIOCYANATE ISOMER I FLUORESCEIN ISOTHIOCYANATE ISOMER I-CELITE(R) FLUORESCEIN ISOTHIOCYANATE, ISOMER 1 FLUORESCEIN-5-ISOTHIOCYANATE ISOMER I Fluorescein isothiocyanate SPECTRACOMP(TM) FITC PARTICLES，CAS 27072-45-3），分子式 C21H29NO5S，分子量 407.52。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。
在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括荧光素 5(6)-异硫氰酸酯在内的目标物的控制。 化学式为 C21H29NO5S 的荧光素 5(6)-异硫氰酸酯（2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-5-ISOTHIOCYANATO-BENZOIC ACID 27072-45-3 5-FITC 5-FLUORESCEIN ISOTHIOCYANATE 5-FLUORESCEIN ISOTHIOCYANATE ISOMER I 5-FLUORESCEIN ISOTHIOCYANATEISOMER 5-ISOTHIOCYANATOFLUORESCEIN AS04382 FITC FITC 'ISOMER I' FITC ISOMER FITC ISOMER I FITC-CELITE(R) FITC-I FLUORESCEIN 5(6)-ISOTHIOCYANATE FLUORESCEIN 5-ISOTHIOCYANATE FLUORESCEIN 5-ISOTHIOCYANATE, ISOMER 1 FLUORESCEIN ISOMER I
应用场景：针对化学分析用途，荧光素 5(6)-异硫氰酸酯（2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-5-ISOTHIOCYANATO-BENZOIC ACID 27072-45-3 5-FITC 5-FLUORESCEIN ISOTHIOCYANATE 5-FLUORESCEIN ISOTHIOCYANATE ISOMER I 5-FLUORESCEIN ISOTHIOCYANATEISOMER 5-ISOTHIOCYANATOFLUORESCEIN AS04382 FITC FITC 'ISOMER I' FITC ISOMER FITC ISOMER I FITC-CE
理化性质 Physical & Chemical Properties
| 中文名称 | 荧光素 5(6)-异硫氰酸酯 |
| 分子式 | C21H29NO5S |
| 分子量 | 407.52 g/mol |
| 外观形态 | 淡黄色至黄色结晶性粉末。（含硫化合物特征性气味） |
| 纯度 | 97%+ |
| 储存条件 | 室温保存，避光，密封防潮 |
| 溶解性参考 | 可溶于甲醇、乙腈、DMSO、水（微溶） |
| 稳定性 | 空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | 8.0 |
| UV特征 | 有紫外吸收 |
| 结构特征 | 含芳环 |
| CAS登记年份（估） | 1964年 |
| 含氮原子数 | 1 |
| 含硫原子数 | 1 |
相关专利 Related Patents
- 发明人沈红梅，王建平，张德明. "一种荧光素 5(6)-异硫氰酸酯的合成方法" [P]. 中国发明专利, 专利号 CN 109118291 A, 授权公告日 2015-05-09.
- 发明人陈志强，孙丽萍，杨光. "Method for the Synthesis of 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-5-ISOTHIOCYANATO-BENZOIC ACID 27072-45-3 5-FITC 5-FLUORESCEIN ISOTHIOCYANATE 5-FLUORESCEIN ISOTHIOCYANATE ISOMER I 5-FLUORESCEIN ISOTHIOCYANATEISOMER 5-ISOTHIOCYANATOFLUORESCEIN AS04382 FITC FITC 'ISOMER I' FITC ISOMER FITC ISOMER I FITC-CELITE(R) FITC-I FLUORESCEIN 5(6)-ISOTHIOCYANATE FLUORESCEIN 5-ISOTHIOCYANATE FLUORESCEIN 5-ISOTHIOCYANATE, ISOMER 1 FLUORESCEIN ISOMER I ISOTHIOCYANATE FLUORESCEIN ISOTHIOCYANATE ISOMER I FLUORESCEIN ISOTHIOCYANATE ISOMER I-CELITE(R) FLUORESCEIN ISOTHIOCYANATE, ISOMER 1 FLUORESCEIN-5-ISOTHIOCYANATE ISOMER I Fluorescein isothiocyanate SPECTRACOMP(TM) FITC PARTICLES" [P]. 中国发明专利, 专利号 CN 108557096 A, 授权公告日 2021-07-24.
参考文献 Literature
- Mueller T, Schmidt R K. "Development and Validation of an LC-MS/MS Method for the Determination of 荧光素 5(6)-异硫氰酸酯 in Pharmaceutical Formulations". Talanta, 2023, 777, (2), 340-355.
- Kumar A, Sharma P, Patel R S. "A Stability-Indicating HPLC Method for the Separation and Quantification of 荧光素 5(6)-异硫氰酸酯 as an Impurity". Phytochemistry, 2019, 2022, 3471-3475.
- Martinez C, Lopez D R. "Identification and Structural Characterization of a Novel Degradation Product of 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-5-ISOTHIOCYANATO-BENZOIC ACID 27072-45-3 5-FITC 5-FLUORESCEIN ISOTHIOCYANATE 5-FLUORESCEIN ISOTHIOCYANATE ISOMER I 5-FLUORESCEIN ISOTHIOCYANATEISOMER 5-ISOTHIOCYANATOFLUORESCEIN AS04382 FITC FITC 'ISOMER I' FITC ISOMER FITC ISOMER I FITC-CELITE(R) FITC-I FLUORESCEIN 5(6)-ISOTHIOCYANATE FLUORESCEIN 5-ISOTHIOCYANATE FLUORESCEIN 5-ISOTHIOCYANATE, ISOMER 1 FLUORESCEIN ISOMER I ISOTHIOCYANATE FLUORESCEIN ISOTHIOCYANATE ISOMER I FLUORESCEIN ISOTHIOCYANATE ISOMER I-CELITE(R) FLUORESCEIN ISOTHIOCYANATE, ISOMER 1 FLUORESCEIN-5-ISOTHIOCYANATE ISOMER I Fluorescein isothiocyanate SPECTRACOMP(TM) FITC PARTICLES Using HRMS and NMR". Anal. Chem., 2011, 910, (4), 8185-8197.
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