1-(4-三氟甲基苯基)哌嗪 CAS 30459-17-7

1-(4-Trifluoromethylphenyl)piperazine 1-(4-trifluoromethyl-phenyl)-piperazine 1-(4-trifluoromethylphenyl)-piperazine 1-[4-(trifluoromethyl)phenyl]piperazine 30459-17-7 n-(4-trifluoro methyl phenyl) piperazine n-(4-trifluoromethylphenyl)piperazine n-(alpha,alpha,alpha-trifluoro-p-tolyl)piperazine

纯度 97%+现货药物标准品
CAS 号30459-17-7
分子式C11H19F3N2
分子量236.28 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

1-(4-三氟甲基苯基)哌嗪 1-(4-Trifluoromethylphenyl)piperazine 1-(4-trifluoromethyl-phenyl)-piperazine 1-(4-trifluoromethylphenyl)-piperazine 1-[4-(trifluoromethyl)phenyl]piperazine 30459-17-7 n-(4-trifluoro methyl phenyl) piperazine n-(4-trifluoromethylphenyl)piperazine n-(alpha,alpha,alpha-trifluoro-p-tolyl)piperazine CAS 30459-17-7 结构式 Chemical Structure

产品介绍 Description

1-(4-三氟甲基苯基)哌嗪（英文名 1-(4-Trifluoromethylphenyl)piperazine 1-(4-trifluoromethyl-phenyl)-piperazine 1-(4-trifluoromethylphenyl)-piperazine 1-[4-(trifluoromethyl)phenyl]piperazine 30459-17-7 n-(4-trifluoro methyl phenyl) piperazine n-(4-trifluoromethylphenyl)piperazine n-(alpha,alpha,alpha-trifluoro-p-tolyl)piperazine，CAS 30459-17-7）属于药物标准品。分子式 C11H19F3N2，分子量 236.28。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

与同类药物标准品相比，1-(4-三氟甲基苯基)哌嗪的分子量为236.28 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 CAS编号 30459-17-7 对应的化合物1-(4-三氟甲基苯基)哌嗪（英文标识 1-(4-Trifluoromethylphenyl)piperazine 1-(4-trifluoromethyl-phenyl)-piperazine 1-(4-trifluoromethylphenyl)-piperazine 1-4-(trifluoromethyl)phenylpiperazine 30459-17-7 n-(4-trifluoro methyl phenyl) piperazine n-(4-trifluoromethylphenyl)piperazine n-(alpha,alpha,alpha-trifluoro-p-tolyl)piperazine），化学式 C11H19F3N2，相对分子质量 236.28。 1-(4-三氟甲基苯基)哌嗪（分子式 C11H19F3N2）的化学结构中包含含氰基，含氟取代。在反相色谱体系中

应用场景：1-(4-三氟甲基苯基)哌嗪（1-(4-Trifluoromethylphenyl)piperazine 1-(4-trifluoromethyl-phenyl)-piperazine 1-(4-trifluoromethylphenyl)-piperazine 1- 4-(trifluoromethyl)phenyl piperazine 30459-17-7 n-(4-trifluoro methyl phenyl) piperazine n-(4-trifluoromethylphenyl)piperazine n-(alpha,alpha,alpha-trifluoro-p-tolyl

理化性质 Physical & Chemical Properties

中文名称1-(4-三氟甲基苯基)哌嗪
分子式C11H19F3N2
分子量236.28 g/mol
外观形态白色至类白色低熔点固体。（具有轻微卤代物特征气味，挥发性较低）
纯度97%+
储存条件2-8°C冷藏保存，避光，密闭保存防止挥发
溶解性参考可溶于DMSO、DMF、甲醇
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）2.0
CAS登记年份（估）1965年
卤素含量F取代
含氮原子数2

相关专利 Related Patents

  1. 发明人高志强，赵玉洁，郭海燕. "一种1-(4-三氟甲基苯基)哌嗪的合成方法" [P]. 中国发明专利, 专利号 CN 109390350 B, 授权公告日 2023-06-20.
  2. 发明人沈红梅，高志强，杨光. "Method for the Synthesis of 1-(4-Trifluoromethylphenyl)piperazine 1-(4-trifluoromethyl-phenyl)-piperazine 1-(4-trifluoromethylphenyl)-piperazine 1-[4-(trifluoromethyl)phenyl]piperazine 30459-17-7 n-(4-trifluoro methyl phenyl) piperazine n-(4-trifluoromethylphenyl)piperazine n-(alpha,alpha,alpha-trifluoro-p-tolyl)piperazine" [P]. 中国发明专利, 专利号 CN 112139968 A, 授权公告日 2020-03-25.

参考文献 Literature

  1. Wang L, Li J, Zhang H. "Development and Validation of an LC-MS/MS Method for the Determination of 1-(4-三氟甲基苯基)哌嗪 in Pharmaceutical Formulations". Chromatographia, 2024, 485, (5), 4807-4817.
  2. Smith J A, Johnson M B. "A Stability-Indicating HPLC Method for the Separation and Quantification of 1-(4-三氟甲基苯基)哌嗪 as an Impurity". J. Nat. Prod., 2019, 1648, 921-934.

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